STRINGSTRING
AXL AXL MUSK MUSK PTK7 PTK7 ENSPTRP00000088414 ENSPTRP00000088414 FGFR3 FGFR3 EPHA1-2 EPHA1-2 YES1 YES1 TNK2 TNK2 BMX BMX ABL2 ABL2 PTK6 PTK6 INSR INSR ERBB4 ERBB4 CK820_G0012168 CK820_G0012168 ENSPTRP00000060289 ENSPTRP00000060289 EPHB1 EPHB1 EPHB2 EPHB2 TYK2 TYK2 BLK BLK LYN LYN FLT4 FLT4 MATK MATK JAK3 JAK3 BTK BTK ROR2 ROR2 PTK2B PTK2B EPHA1 EPHA1 EPHB4 EPHB4 FRK FRK EPHA7 EPHA7 FGFR4 FGFR4 ITK ITK FER FER EPHA5 EPHA5 KDR KDR KIT KIT PDGFRA PDGFRA RYK RYK EPHA6 EPHA6 EPHA3 EPHA3 MST1R MST1R SRMS SRMS HCK HCK ZAP70 ZAP70 ALK ALK TNK1 TNK1 IGF1R IGF1R FES FES CSK CSK TYRO3 TYRO3 LTK LTK MAP3K9 MAP3K9 FLT1 FLT1 FLT3 FLT3 ERBB3 ERBB3 MAP3K11 MAP3K11 FGFR2 FGFR2 RET RET MAP3K21 MAP3K21 DDR2 DDR2 JAK1 JAK1 TIE1 TIE1 EPHA10 EPHA10 LCK LCK FGR FGR EPHA8 EPHA8 EPHA2 EPHA2 FGFR1 FGFR1 DDR1 DDR1 EGFR EGFR ERBB2 ERBB2 TEK TEK INSRR INSRR TEC TEC ENSPTRP00000072507 ENSPTRP00000072507 ABL1 ABL1 EPHB3 EPHB3 SYK SYK MERTK MERTK SRC SRC NTRK2 NTRK2 FYN FYN EPHB4-2 EPHB4-2 TXK-2 TXK-2 PDGFRB PDGFRB ROS1 ROS1 CSF1R CSF1R ENSPTRP00000081537 ENSPTRP00000081537 JAK2 JAK2 MET MET NTRK1 NTRK1 PTK2 PTK2 NTRK3 NTRK3 TXK TXK EPHA4 EPHA4 ROR1 ROR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AXLAXL receptor tyrosine kinase. (894 aa)
MUSKMuscle associated receptor tyrosine kinase. (879 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
ENSPTRP00000088414annotation not available (529 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
EPHA1-2EPH receptor A1. (976 aa)
YES1Tyrosine-protein kinase. (558 aa)
TNK2TNK2 isoform 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
BMXTyrosine-protein kinase. (679 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
PTK6Tyrosine-protein kinase. (451 aa)
INSRTyrosine-protein kinase receptor. (1408 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
ENSPTRP00000060289annotation not available (844 aa)
EPHB1EPH receptor B1. (984 aa)
EPHB2EPH receptor B2. (1055 aa)
TYK2Tyrosine-protein kinase. (1184 aa)
BLKTyrosine-protein kinase. (505 aa)
LYNTyrosine-protein kinase. (512 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa)
MATKTyrosine-protein kinase. (508 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
BTKBTK isoform 2. (693 aa)
ROR2Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
EPHA1EPH receptor A1. (976 aa)
EPHB4EPH receptor B4. (987 aa)
FRKTyrosine-protein kinase. (505 aa)
EPHA7EPHA7 isoform 2. (998 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
ITKTyrosine-protein kinase. (620 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
EPHA5EPH receptor A5. (1038 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
PDGFRAT0011027 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1102 aa)
RYKReceptor like tyrosine kinase. (610 aa)
EPHA6EPH receptor A6. (1130 aa)
EPHA3EPH receptor A3. (983 aa)
MST1RMacrophage stimulating 1 receptor. (1400 aa)
SRMSTyrosine-protein kinase. (447 aa)
HCKTyrosine-protein kinase. (526 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
ALKTyrosine-protein kinase receptor. (1620 aa)
TNK1TNK1 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (661 aa)
IGF1RTyrosine-protein kinase receptor. (1364 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
CSKTyrosine-protein kinase. (450 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
LTKTyrosine-protein kinase receptor. (864 aa)
MAP3K9MAP3K9 isoform 3. (1119 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
ERBB3V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian). (1353 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11 isoform X2. (847 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1036 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
EPHA10EPH receptor A10. (1014 aa)
LCKTyrosine-protein kinase. (539 aa)
FGRTyrosine-protein kinase. (529 aa)
EPHA8EPHA8 isoform 1. (997 aa)
EPHA2EPH receptor A2. (976 aa)
FGFR1Fibroblast growth factor receptor. (854 aa)
DDR1Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes sm [...] (920 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
INSRRTyrosine-protein kinase receptor. (1297 aa)
TECTyrosine-protein kinase. (631 aa)
ENSPTRP00000072507annotation not available (659 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
EPHB3EPHB3 isoform 1. (1031 aa)
SYKTyrosine-protein kinase. (635 aa)
MERTKMERTK isoform 1. (963 aa)
SRCTyrosine-protein kinase. (542 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
FYNTyrosine-protein kinase. (537 aa)
EPHB4-2EPH receptor B4. (987 aa)
TXK-2TXK tyrosine kinase. (530 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ROS1Proto-oncogene tyrosine-protein kinase ROS isoform X5. (2347 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
ENSPTRP00000081537annotation not available (449 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa)
TXKTyrosine-protein kinase. (527 aa)
EPHA4EPH receptor A4. (986 aa)
ROR1Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (945 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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