27 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	PLXNB1	PLXNB1 isoform 1. (2135 aa)
	EBF4	EBF4 isoform 5. (616 aa)
	PLXNC1	PLXNC1 isoform 1. (1568 aa)
	PLXNB2	PLXNB2 isoform 1. (1838 aa)
	PLXNB3	PLXNB3 isoform 1. (1932 aa)
	NFATC4	Nuclear factor of activated T cells 4. (933 aa)
	PLXNA1	PLXNA1 isoform 1. (1915 aa)
	EBF3	EBF transcription factor 3. (621 aa)
	EBF2	EBF transcription factor 2. (575 aa)
	MET	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa)
	RELB	RELB isoform 3. (567 aa)
	NFATC3	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa)
	REL	REL isoform 1. (619 aa)
	NFAT5	Nuclear factor of activated T-cells 5, tonicity-responsive. (1548 aa)
	NFKB2	Nuclear factor kappa B subunit 2. (900 aa)
	NFATC1	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1. (853 aa)
	PLXNA4	PLXNA4 isoform 1. (1894 aa)
	RELA	V-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
	PKHD1L1	PKHD1L1 isoform 1. (4264 aa)
	NFATC2	NFATC2 isoform 4. (938 aa)
	PLXNA3	PLXNA3 isoform 1. (1871 aa)
	PKHD1	PKHD1 isoform 1. (4074 aa)
	EBF1	EBF transcription factor 1. (591 aa)
	NFKB1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (969 aa)
	PLXND1	PLXND1 isoform 1. (1925 aa)
	MST1R	Macrophage stimulating 1 receptor. (1400 aa)
	PLXNA2	PLXNA2 isoform 1. (1909 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EBF1	NFKB1	ENSPTRP00000029857	ENSPTRP00000028033	EBF transcription factor 1.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.	0.465
MET	MST1R	ENSPTRP00000083162	ENSPTRP00000025788	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.738
MET	PLXNA1	ENSPTRP00000083162	ENSPTRP00000088978	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNA1 isoform 1.	0.410
MET	PLXNA2	ENSPTRP00000083162	ENSPTRP00000003263	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNA2 isoform 1.	0.410
MET	PLXNA3	ENSPTRP00000083162	ENSPTRP00000038678	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNA3 isoform 1.	0.410
MET	PLXNA4	ENSPTRP00000083162	ENSPTRP00000059933	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNA4 isoform 1.	0.410
MET	PLXNB1	ENSPTRP00000083162	ENSPTRP00000025675	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNB1 isoform 1.	0.997
MET	PLXNB2	ENSPTRP00000083162	ENSPTRP00000077349	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNB2 isoform 1.	0.966
MET	PLXNB3	ENSPTRP00000083162	ENSPTRP00000092121	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNB3 isoform 1.	0.969
MET	PLXNC1	ENSPTRP00000083162	ENSPTRP00000076288	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXNC1 isoform 1.	0.410
MET	PLXND1	ENSPTRP00000083162	ENSPTRP00000026498	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	PLXND1 isoform 1.	0.410
MST1R	MET	ENSPTRP00000025788	ENSPTRP00000083162	Macrophage stimulating 1 receptor.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.738
MST1R	PLXNA1	ENSPTRP00000025788	ENSPTRP00000088978	Macrophage stimulating 1 receptor.	PLXNA1 isoform 1.	0.562
MST1R	PLXNA2	ENSPTRP00000025788	ENSPTRP00000003263	Macrophage stimulating 1 receptor.	PLXNA2 isoform 1.	0.410
MST1R	PLXNA3	ENSPTRP00000025788	ENSPTRP00000038678	Macrophage stimulating 1 receptor.	PLXNA3 isoform 1.	0.421
MST1R	PLXNA4	ENSPTRP00000025788	ENSPTRP00000059933	Macrophage stimulating 1 receptor.	PLXNA4 isoform 1.	0.410
MST1R	PLXNB1	ENSPTRP00000025788	ENSPTRP00000025675	Macrophage stimulating 1 receptor.	PLXNB1 isoform 1.	0.719
MST1R	PLXNB2	ENSPTRP00000025788	ENSPTRP00000077349	Macrophage stimulating 1 receptor.	PLXNB2 isoform 1.	0.544
MST1R	PLXNB3	ENSPTRP00000025788	ENSPTRP00000092121	Macrophage stimulating 1 receptor.	PLXNB3 isoform 1.	0.554
MST1R	PLXNC1	ENSPTRP00000025788	ENSPTRP00000076288	Macrophage stimulating 1 receptor.	PLXNC1 isoform 1.	0.410