67 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNA15	G protein subunit alpha 15. (374 aa)
	GNAI3	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
	NRAS	Neuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	HRAS	V-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	AKAP3	A-kinase anchoring protein 3. (858 aa)
	PDE1B	Phosphodiesterase. (536 aa)
	AKAP11	A kinase (PRKA) anchor protein 11. (1901 aa)
	ADCY4	Adenylate cyclase type 4 isoform X1. (1077 aa)
	AKAP6	A-kinase anchoring protein 6. (2319 aa)
	PRKCH	Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
	PDE8A	Phosphodiesterase. (829 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	AKAP1	A-kinase anchoring protein 1. (903 aa)
	GNA13	Guanine nucleotide binding protein (G protein), alpha 13. (377 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	RRAS	Related RAS viral (R-ras) oncogene homolog. (218 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	PRKD3	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
	KCNJ3	Potassium voltage-gated channel subfamily J member 3. (501 aa)
	GNAZ	G protein subunit alpha z. (355 aa)
	ITPR1	ITPR1 isoform 3. (2700 aa)
	RHOA	Ras homolog family member A. (193 aa)
	GNAI2	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (355 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa)
	AKAP7	A-kinase anchoring protein 7. (348 aa)
	PDE7B	Phosphodiesterase. (502 aa)
	GNA12	Guanine nucleotide binding protein (G protein) alpha 12. (381 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	PRKACG	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
	AKAP13	A-kinase anchoring protein 13. (2813 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	PRKAR1A	Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1). (381 aa)
	AKAP9	A kinase (PRKA) anchor protein (Yotiao) 9. (3908 aa)
	AKAP5	A-kinase anchoring protein 5. (427 aa)
	PDE7A	Phosphodiesterase. (482 aa)
	GNAS	GNAS isoform 19. (1042 aa)
	PRKAR2B	Protein kinase, cAMP-dependent, regulatory, type II, beta. (418 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
	AKAP10	A kinase (PRKA) anchor protein 10. (662 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	PDE4B	Phosphodiesterase. (736 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
	GNB1	Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
	PDE4D	Phosphodiesterase. (809 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	PDE4C	Phosphodiesterase. (713 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNAI1	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. (422 aa)
	AKAP4	A-kinase anchoring protein 4. (845 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (521 aa)
	PDE8B	Phosphodiesterase. (885 aa)
	GNAL	G protein subunit alpha L. (458 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (845 aa)
	PDE1A	Phosphodiesterase. (572 aa)
	AKAP8	A kinase (PRKA) anchor protein 8; Belongs to the AKAP95 family. (692 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	GNB2	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	GNAO1	G protein subunit alpha o1. (354 aa)
	GNA14	Guanine nucleotide binding protein (G protein), alpha 14. (355 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY3	ENSPTRP00000032741	ENSPTRP00000020130	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.935
ADCY1	ADCY7	ENSPTRP00000032741	ENSPTRP00000062799	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.521
ADCY1	ADCY8	ENSPTRP00000032741	ENSPTRP00000077396	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY9	ENSPTRP00000032741	ENSPTRP00000013173	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.633
ADCY1	GNAI1	ENSPTRP00000032741	ENSPTRP00000071974	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.815
ADCY1	GNAI2	ENSPTRP00000032741	ENSPTRP00000025802	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.797
ADCY1	GNAI3	ENSPTRP00000032741	ENSPTRP00000001821	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.846
ADCY1	GNAL	ENSPTRP00000032741	ENSPTRP00000077082	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.857
ADCY1	GNAO1	ENSPTRP00000032741	ENSPTRP00000088044	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha o1.	0.944
ADCY1	GNAS	ENSPTRP00000032741	ENSPTRP00000059419	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS isoform 19.	0.973
ADCY1	GNAZ	ENSPTRP00000032741	ENSPTRP00000024336	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha z.	0.547
ADCY1	GNB1	ENSPTRP00000032741	ENSPTRP00000067330	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.860
ADCY1	GNB2	ENSPTRP00000032741	ENSPTRP00000085287	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.791
ADCY1	GNG11	ENSPTRP00000032741	ENSPTRP00000033202	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.785
ADCY1	GNG3	ENSPTRP00000032741	ENSPTRP00000006503	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.788
ADCY1	GNG4	ENSPTRP00000032741	ENSPTRP00000003602	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.789
ADCY1	GNG7	ENSPTRP00000032741	ENSPTRP00000069136	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.821
ADCY1	GNGT1	ENSPTRP00000032741	ENSPTRP00000033201	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.785
ADCY1	GNGT2	ENSPTRP00000032741	ENSPTRP00000060750	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.811
ADCY1	PDE1A	ENSPTRP00000032741	ENSPTRP00000082071	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.677