(18 nodes) Fatty acid biosynthesis network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MECR	Mitochondrial trans-2-enoyl-CoA reductase. (297 aa)
	ACSBG1	Acyl-CoA synthetase bubblegum family member 1. (724 aa)
	FASN	Fatty acid synthase. (2511 aa)
	ACSBG2	ACSBG2 isoform 5. (666 aa)
	ACSL3	Acyl-CoA synthetase long-chain family member 3. (720 aa)
	MCAT	Malonyl CoA:ACP acyltransferase (Mitochondrial). (390 aa)
	ACSL1	ACSL1 isoform 9. (698 aa)
	HSD17B8	Hydroxysteroid (17-beta) dehydrogenase 8. (261 aa)
	ACSL4	Acyl-CoA synthetase long-chain family member 4. (749 aa)
	ACSL5	Acyl-CoA synthetase long-chain family member 5. (739 aa)
	CBR4	Carbonyl reductase 4. (237 aa)
	HTD2	Ribonuclease P/MRP 14kDa subunit. (164 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (2383 aa)
	ACSF3	ACSF3 isoform 1. (576 aa)
	ACACB	ACACB isoform 2. (2458 aa)
	OXSM	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (459 aa)
	OLAH	OLAH isoform 2. (312 aa)
	ACSL6	T0093412 isoform 1. (722 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACACB	ENSPTRP00000074254	ENSPTRP00000079596	Acetyl-CoA carboxylase alpha.	ACACB isoform 2.	0.934
ACACA	ACSF3	ENSPTRP00000074254	ENSPTRP00000077318	Acetyl-CoA carboxylase alpha.	ACSF3 isoform 1.	0.914
ACACA	ACSL1	ENSPTRP00000074254	ENSPTRP00000028542	Acetyl-CoA carboxylase alpha.	ACSL1 isoform 9.	0.678
ACACA	ACSL3	ENSPTRP00000074254	ENSPTRP00000022173	Acetyl-CoA carboxylase alpha.	Acyl-CoA synthetase long-chain family member 3.	0.611
ACACA	ACSL4	ENSPTRP00000074254	ENSPTRP00000038175	Acetyl-CoA carboxylase alpha.	Acyl-CoA synthetase long-chain family member 4.	0.421
ACACA	ACSL6	ENSPTRP00000074254	ENSPTRP00000088489	Acetyl-CoA carboxylase alpha.	T0093412 isoform 1.	0.505
ACACA	FASN	ENSPTRP00000074254	ENSPTRP00000016660	Acetyl-CoA carboxylase alpha.	Fatty acid synthase.	0.991
ACACA	MCAT	ENSPTRP00000074254	ENSPTRP00000024925	Acetyl-CoA carboxylase alpha.	Malonyl CoA:ACP acyltransferase (Mitochondrial).	0.954
ACACA	OXSM	ENSPTRP00000074254	ENSPTRP00000085652	Acetyl-CoA carboxylase alpha.	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.631
ACACB	ACACA	ENSPTRP00000079596	ENSPTRP00000074254	ACACB isoform 2.	Acetyl-CoA carboxylase alpha.	0.934
ACACB	ACSF3	ENSPTRP00000079596	ENSPTRP00000077318	ACACB isoform 2.	ACSF3 isoform 1.	0.914
ACACB	ACSL1	ENSPTRP00000079596	ENSPTRP00000028542	ACACB isoform 2.	ACSL1 isoform 9.	0.502
ACACB	ACSL3	ENSPTRP00000079596	ENSPTRP00000022173	ACACB isoform 2.	Acyl-CoA synthetase long-chain family member 3.	0.470
ACACB	FASN	ENSPTRP00000079596	ENSPTRP00000016660	ACACB isoform 2.	Fatty acid synthase.	0.970
ACACB	MCAT	ENSPTRP00000079596	ENSPTRP00000024925	ACACB isoform 2.	Malonyl CoA:ACP acyltransferase (Mitochondrial).	0.950
ACACB	OXSM	ENSPTRP00000079596	ENSPTRP00000085652	ACACB isoform 2.	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.631
ACSBG1	ACSBG2	ENSPTRP00000012543	ENSPTRP00000017616	Acyl-CoA synthetase bubblegum family member 1.	ACSBG2 isoform 5.	0.612
ACSBG1	ACSL1	ENSPTRP00000012543	ENSPTRP00000028542	Acyl-CoA synthetase bubblegum family member 1.	ACSL1 isoform 9.	0.685
ACSBG1	ACSL3	ENSPTRP00000012543	ENSPTRP00000022173	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase long-chain family member 3.	0.763
ACSBG1	ACSL4	ENSPTRP00000012543	ENSPTRP00000038175	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase long-chain family member 4.	0.762