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AGMAT AGMAT ALDH4A1 ALDH4A1 AZIN2 AZIN2 ALDH9A1 ALDH9A1 GOT1 GOT1 OAT OAT P4HA3 P4HA3 L3HYPDH L3HYPDH ARG2 ARG2 CKB CKB GATM GATM GOT2 GOT2 CNDP2 CNDP2 PRODH2 PRODH2 CKM CKM ODC1 ODC1 LAP3 LAP3 AMD1 AMD1 ARG1 ARG1 PYCR3 PYCR3 ALDH1B1 ALDH1B1 SAT1-2 SAT1-2 MAOA MAOA MAOB MAOB PYCR1 PYCR1 AOC1 AOC1 CKMT2 CKMT2 GAMT GAMT LOC742521 LOC742521 CNDP1 CNDP1 SMS SMS ALDH7A1 ALDH7A1 SRM SRM PRODH PRODH LOC453384 LOC453384 ALDH18A1 ALDH18A1 DAO DAO ALDH3A2 ALDH3A2 CARNS1 CARNS1 PYCR2 PYCR2 P4HA2 P4HA2 ALDH2 ALDH2 SMOX SMOX NOS1 NOS1 GOT1L1 GOT1L1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGMATAGMAT isoform 1; Belongs to the arginase family. (352 aa)
ALDH4A1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
AZIN2Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (460 aa)
ALDH9A1Aldehyde dehydrogenase 9 family, member A1; Belongs to the aldehyde dehydrogenase family. (518 aa)
GOT1Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (413 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
P4HA3P4HA3 isoform 4. (544 aa)
L3HYPDHChromosome 14 open reading frame 149. (354 aa)
ARG2Arginase. (354 aa)
CKBCreatine kinase, brain; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
GATMGlycine amidinotransferase. (423 aa)
GOT2Aspartate aminotransferase. (430 aa)
CNDP2CNDP dipeptidase 2 (Metallopeptidase M20 family). (475 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (536 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
ODC1Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
LAP3Leucine aminopeptidase 3. (519 aa)
AMD1S-adenosylmethionine decarboxylase proenzyme. (334 aa)
ARG1Arginase. (322 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (286 aa)
ALDH1B1Aldehyde dehydrogenase 1 family, member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
SAT1-2Spermidine/spermine N1-acetyltransferase 1. (171 aa)
MAOAAmine oxidase. (527 aa)
MAOBAmine oxidase. (520 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
AOC1Amine oxidase. (755 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
GAMTGuanidinoacetate N-methyltransferase. (269 aa)
LOC742521CKMT1A isoform 1; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
CNDP1Carnosine dipeptidase 1. (527 aa)
SMSSMS isoform 1. (358 aa)
ALDH7A1ALDH7A1 isoform 8; Belongs to the aldehyde dehydrogenase family. (556 aa)
SRMSpermidine synthase; Belongs to the spermidine/spermine synthase family. (315 aa)
PRODHProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (268 aa)
LOC453384Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
DAOD-amino acid oxidase. (347 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
CARNS1Carnosine synthase 1. (950 aa)
PYCR2PYCR1 isoform 17. (320 aa)
P4HA2Prolyl 4-hydroxylase, alpha polypeptide II. (535 aa)
ALDH2T0055793 isoform 1. (517 aa)
SMOXSpermine oxidase. (585 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
GOT1L1GOT1L1 isoform 1. (415 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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