STRINGSTRING
LOC746545 LOC746545 PCBD1 PCBD1 PAH PAH MOCOS MOCOS ALPP ALPP ALPI ALPI CBR1 CBR1 QDPR QDPR MOCS2 MOCS2 DHFR DHFR PCBD2 PCBD2 AKR1B1 AKR1B1 GGH GGH PTS PTS AKR1B10 AKR1B10 GCH1 GCH1 AKR1B15 AKR1B15 MOCS1 MOCS1 ALPL ALPL SPR SPR TPH1 TPH1 AKR1C3 AKR1C3 FPGS FPGS TPH2 TPH2 GPHN GPHN DHFR2 DHFR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC746545Aldo-keto reductase family 1 member C3. (303 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha. (104 aa)
PAHPhenylalanine hydroxylase. (452 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (888 aa)
ALPPAlkaline phosphatase. (534 aa)
ALPIAlkaline phosphatase. (528 aa)
CBR1Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
QDPRQuinoid dihydropteridine reductase. (244 aa)
MOCS2Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. (188 aa)
DHFRDihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
PCBD2Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa)
AKR1B1Aldo-keto reductase family 1, member B1 (Aldose reductase). (316 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
AKR1B10AKR1B10 isoform 1. (316 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
AKR1B15AKR1B15 isoform 1. (344 aa)
MOCS1Molybdenum cofactor synthesis 1. (636 aa)
ALPLAlkaline phosphatase. (524 aa)
SPRSepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase). (261 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
AKR1C3Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II). (323 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (587 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (782 aa)
DHFR2DHFR2 isoform 2. (186 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.