STRINGSTRING
GSTM1 GSTM1 GSTM5 GSTM5 FMO5 FMO5 MGST3 MGST3 FMO3 FMO3 FMO2 FMO2 FMO4 FMO4 CYP2C9 CYP2C9 CYP2C8 CYP2C8 CYP2E1 CYP2E1 LOC470264 LOC470264 UGT2B4 UGT2B4 HPGDS HPGDS ADH5 ADH5 ADH6 ADH6 ADH1A ADH1A MGST2 MGST2 GSTA1 GSTA1 GSTA4 GSTA4 CYP3A5 CYP3A5 MAOA MAOA MAOB MAOB CYP2B6 CYP2B6 CYP2D6 CYP2D6 GSTP1 GSTP1 AOX1 AOX1 GSTA2 GSTA2 ALDH3A1 ALDH3A1 UGT2A3 UGT2A3 GSTM4 GSTM4 GSTO1 GSTO1 UGT2B7 UGT2B7 ADH7 ADH7 ALDH3B1 ALDH3B1 GSTA5 GSTA5 LOC472094 LOC472094 GSTM3-2 GSTM3-2 MGST1 MGST1 ADH4 ADH4 CYP1A2 CYP1A2 ADH1B ADH1B UGT2B10 UGT2B10 GSTA3 GSTA3 LOC469566 LOC469566 CYP3A4 CYP3A4 UGT1A3 UGT1A3 ALDH3B2 ALDH3B2 GSTO2 GSTO2 GSTK1-2 GSTK1-2 LOC471219 LOC471219
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSTM1GSTM1 isoform 3; Belongs to the GST superfamily. (218 aa)
GSTM5Glutathione S-transferase. (217 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
MGST3Microsomal glutathione S-transferase 3. (165 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] (532 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming] 2; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. (535 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
CYP2C9Cytochrome P450 family 2 subfamily C member 9; Belongs to the cytochrome P450 family. (490 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (490 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (531 aa)
LOC470264Glutathione S-transferase theta 1; Belongs to the GST superfamily. (240 aa)
UGT2B4UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa)
ADH6Alcohol dehydrogenase 6 (class V). (375 aa)
ADH1AAlcohol dehydrogenase 1A (class I), alpha polypeptide. (375 aa)
MGST2Microsomal glutathione S-transferase 2. (147 aa)
GSTA1Glutathione S-transferase. (222 aa)
GSTA4Glutathione S-transferase alpha 4. (222 aa)
CYP3A5CYP3A5 isoform 1. (493 aa)
MAOAAmine oxidase. (527 aa)
MAOBAmine oxidase. (520 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (491 aa)
CYP2D6Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...] (488 aa)
GSTP1Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
AOX1Aldehyde oxidase 1. (1338 aa)
GSTA2Glutathione S-transferase alpha 2. (222 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
UGT2A3UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
GSTM4Glutathione S-transferase mu 4; Belongs to the GST superfamily. (218 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
UGT2B7UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
ADH7ADH7 isoform 5. (394 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
GSTA5Glutathione S-transferase alpha 5; Belongs to the GST superfamily. (222 aa)
LOC472094Glutathione S-transferase Mu 2-like. (196 aa)
GSTM3-2Glutathione S-transferase. (225 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (399 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (517 aa)
ADH1BAll-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. (375 aa)
UGT2B10UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
GSTA3Glutathione S-transferase alpha 3; Belongs to the GST superfamily. (192 aa)
LOC469566LOW QUALITY PROTEIN: dimethylaniline monooxygenase [N-oxide-forming] 5-like. (484 aa)
CYP3A4Cytochrome P450 family 3 subfamily A member 4. (507 aa)
UGT1A3UDP-glucuronosyltransferase 1-3 isoform X2. (534 aa)
ALDH3B2Aldehyde dehydrogenase 3 family member B2; Belongs to the aldehyde dehydrogenase family. (487 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
GSTK1-2Glutathione S-transferase kappa 1. (282 aa)
LOC471219UDP-glucuronosyltransferase 2B10 isoform X1. (529 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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