ATP binding cassette subfamily C member 2.

ATPase, Cu++ transporting, alpha polypeptide.

ATP binding cassette subfamily C member 2.

Glutathione S-transferase pi 1; Belongs to the GST superfamily.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Bcl2-associated agonist of cell death.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

BCL2 apoptosis regulator.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

BCL2L1 isoform 6.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Baculoviral IAP repeat containing 2.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Baculoviral IAP repeat containing 3.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

CASP9 isoform 4; Belongs to the peptidase C14A family.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Cyclin-dependent kinase inhibitor 1A (P21, Cip1).

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).

AKT1 isoform 3; Belongs to the protein kinase superfamily.

Receptor protein-tyrosine kinase.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

AKT1 isoform 3; Belongs to the protein kinase superfamily.

FASLG isoform 1; Belongs to the tumor necrosis factor family.