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| | TARDBP | TAR DNA binding protein. (414 aa) |
| | SRRM1 | SRRM1 isoform 3. (918 aa) |
| | EIF3I | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa) |
| | MAGOH | Mago-nashi homolog, proliferation-associated. (146 aa) |
| | DDX20 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20. (861 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa) |
| | NUP133 | NUP133 isoform 1. (1156 aa) |
| | UPF2 | UPF2 regulator of nonsense mediated mRNA decay. (1272 aa) |
| | RPP38 | Ribonuclease P/MRP 38kDa subunit. (311 aa) |
| | EIF4EBP2 | Eukaryotic translation initiation factor 4E binding protein 2. (120 aa) |
| | EIF3F | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (361 aa) |
| | EIF4G2 | Eukaryotic translation initiation factor 4 gamma 2. (920 aa) |
| | NXF1 | Nuclear RNA export factor 1. (619 aa) |
| | AAAS | Achalasia, adrenocortical insufficiency, alacrimia. (546 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa) |
| | NUP37 | Nucleoporin 37kDa. (326 aa) |
| | EIF2B1 | Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa) |
| | SAP18 | Sin3A associated protein 18. (172 aa) |
| | ACIN1 | ACIN1 isoform 7. (1342 aa) |
| | GEMIN2 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (280 aa) |
| | PNN | Pinin, desmosome associated protein. (719 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa. (315 aa) |
| | EIF2B2 | Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa) |
| | EIF5 | Eukaryotic translation initiation factor 5. (431 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | RPP25 | Ribonuclease P and MRP subunit p25. (199 aa) |
| | SNUPN | Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family. (360 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (198 aa) |
| | EIF3C | Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (311 aa) |
| | GEMIN4 | Gem (Nuclear organelle) associated protein 4. (1058 aa) |
| | NUP88 | NUP88 isoform 1. (741 aa) |
| | EIF4A1 | Eukaryotic initiation factor 4A-I; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). (406 aa) |
| | FXR2 | Fragile X mental retardation, autosomal homolog 2. (673 aa) |
| | EIF1 | Eukaryotic translation initiation factor 1. (113 aa) |
| | KPNB1 | Karyopherin (Importin) beta 1. (876 aa) |
| | THOC1 | THOC1 isoform 2. (664 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa) |
| | ELAC1 | ElaC ribonuclease Z 1. (363 aa) |
| | EIF3G | Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa) |
| | POP4 | Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (220 aa) |
| | EIF2B4 | Eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa) |
| | GEMIN6 | Gem (Nuclear organelle) associated protein 6. (167 aa) |
| | RANBP2-2 | E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...] (439 aa) |
| | NUP35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa) |
| | NXT1 | Nuclear transport factor 2 like export factor 1. (140 aa) |
| | EIF2S2 | Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa. (333 aa) |
| | PABPC1L | Poly(A) binding protein cytoplasmic 1 like. (330 aa) |
| | EEF1A2 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa) |
| | EIF3D | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa) |
| | TRNT1 | tRNA nucleotidyl transferase, CCA-adding, 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (434 aa) |
| | NUP210 | NUP210 isoform 1. (1887 aa) |
| | EIF1B | Eukaryotic translation initiation factor 1B. (113 aa) |
| | THOC7 | THO complex 7 homolog. (204 aa) |
| | FXR1 | Fragile X mental retardation, autosomal homolog 1. (782 aa) |
| | EIF2B5 | Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa) |
| | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1. (1559 aa) |
| | SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2. (589 aa) |
| | EIF4A2 | Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (408 aa) |
| | TACC3 | Transforming acidic coiled-coil containing protein 3. (838 aa) |
| | PHAX | Phosphorylated adaptor for RNA export. (394 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1508 aa) |
| | POM121L2 | POM121L2 isoform 2. (1035 aa) |
| | XPO5 | XPO5 isoform 1. (1204 aa) |
| | POM121C | POM121C isoform 4. (1229 aa) |
| | POP7 | Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa) |
| | TGS1 | Trimethylguanosine synthase 1. (855 aa) |
| | POP1 | Processing of 1, ribonuclease P/MRP subunit. (1024 aa) |
| | RPP25L | Ribonuclease P/MRP subunit p25 like. (163 aa) |
| | UPF3B | UPF3B regulator of nonsense mediated mRNA decay. (483 aa) |
| | FMR1 | Fragile X mental retardation 1. (632 aa) |
| | EIF1AY | Eukaryotic translation initiation factor 1A, Y-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity); Belongs to the eIF-1A family. (144 aa) |
| | PABPC4 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa) |
| | THOC5 | THOC5 isoform 1. (683 aa) |
| | XPO1 | XPO1 isoform 1. (1071 aa) |
| | PABPC3 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (633 aa) |
| | GLE1 | GLE1 RNA export mediator homolog. (690 aa) |
| | EEF1A1 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (462 aa) |
| | THOC3 | THOC3 isoform 4. (351 aa) |
| | EIF4E1B | Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (242 aa) |
| | NUP160 | NUP160 isoform 2. (1436 aa) |
| | PAIP1 | Poly(A) binding protein interacting protein 1. (479 aa) |
| | XPOT | Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa) |
| | TPR | Translocated promoter region (To activated MET oncogene). (2363 aa) |
| | EIF5B | Eukaryotic translation initiation factor 5B. (1220 aa) |
| | RAE1 | RAE1 RNA export 1 homolog. (368 aa) |
| | FUS | FUS isoform 7. (526 aa) |
| | DDX39B | Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa) |
| | EIF2S3B | Eukaryotic translation initiation factor 2 subunit gamma B. (466 aa) |
| | PABPC5 | Polyadenylate-binding protein 5; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). (382 aa) |
| | NXF5 | NXF5 isoform 2. (397 aa) |
| | PABPC1L2A | PABPC1L2A isoform 1. (200 aa) |
| | SUMO2 | Small ubiquitin-related modifier. (145 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1, 80kDa. (790 aa) |
| | GEMIN7 | GEMIN7 isoform 6. (131 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa) |
| | EIF3B | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (819 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | EIF2B3 | Eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa. (452 aa) |
| | NUP42 | NUPL2 isoform 7. (448 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa) |
| | RPP30 | Ribonuclease P/MRP subunit p30. (322 aa) |
| | RNPS1 | RNA binding protein with serine rich domain 1. (305 aa) |
| | NDC1 | Transmembrane protein 48. (776 aa) |
| | NUP153 | NUP153 isoform 1. (1506 aa) |
| | PABPC4L | PABPC4L isoform 1. (430 aa) |
| | LOC455519 | EIF2S3 isoform 1. (454 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1129 aa) |
| | UPF3A | UPF3A isoform 1. (476 aa) |
| | EIF4E | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (247 aa) |
| | PABPC1 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa) |
| | EIF3H | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa) |
| | LOC736868 | Protein mago nashi homolog. (148 aa) |
| | SEC13 | SEC13 isoform 7; Belongs to the WD repeat SEC13 family. (368 aa) |
| | NUP43 | Nucleoporin 43kDa. (380 aa) |
| | ENSPTRP00000072120 | Eukaryotic translation initiation factor 3 subunit C. (66 aa) |
| | NUP188-2 | Nucleoporin 188kDa. (1763 aa) |
| | CK820_G0055937 | NXF2B isoform 3. (624 aa) |
| | STRAP | Serine/threonine kinase receptor associated protein. (363 aa) |
| | GEMIN8 | Gem (Nuclear organelle) associated protein 8. (243 aa) |
| | POM121 | POM121 isoform 5. (1219 aa) |
| | EIF3J | Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (259 aa) |
| | NUP155 | Nucleoporin 155kDa. (1391 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (496 aa) |
| | NMD3 | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa) |
| | NUP214 | NUP214 isoform 1. (2090 aa) |
| | NUP58 | Nucleoporin like 1. (603 aa) |
| | ELAC2 | Zinc phosphodiesterase ELAC protein 2; Zinc phosphodiesterase, which displays mitochondrial tRNA 3'- processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity). (826 aa) |
| | RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (234 aa) |
| | NXT2 | Nuclear transport factor 2 like export factor 2. (197 aa) |
| | EIF4G3 | EIF4G3 isoform 5. (1776 aa) |
| | SUMO3-2 | Small ubiquitin-related modifier. (103 aa) |
| | NUP205 | Nucleoporin 205kDa. (2017 aa) |
| | NUP98 | Nucleoporin 98kDa. (1800 aa) |
| | RPP40 | Ribonuclease P/MRP 40kDa subunit. (363 aa) |
| | CLNS1A | Chloride channel, nucleotide-sensitive, 1A. (237 aa) |
| | DDX19B | DEAD (Asp-Glu-Ala-As) box polypeptide 19A. (446 aa) |
| | NUP50 | Nucleoporin 50kDa. (468 aa) |
| | PYM1 | PYM homolog 1, exon junction complex associated factor. (204 aa) |
| | RPP14 | Ribonuclease P/MRP subunit p14. (124 aa) |
| | ALYREF | Aly/REF export factor. (285 aa) |
| | EIF4B | Eukaryotic translation initiation factor 4B. (615 aa) |
| | EIF4E2 | Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (249 aa) |
