STRINGSTRING
TARDBP TARDBP SRRM1 SRRM1 MAGOH MAGOH RBM8A RBM8A UPF2 UPF2 PPP2R2D PPP2R2D CSTF3 CSTF3 CPSF7 CPSF7 NXF1 NXF1 PPP2R5B PPP2R5B PCF11 PCF11 PPP2R1B PPP2R1B SAP18 SAP18 ACIN1 ACIN1 PPP2R3C PPP2R3C PNN PNN CPSF2 CPSF2 PAPOLA PAPOLA PPP2R5C PPP2R5C GSPT1 GSPT1 NUDT21 NUDT21 SMG6 SMG6 MSI2 MSI2 CPSF4L CPSF4L CPSF3 CPSF3 PAPOLG PAPOLG WDR33 WDR33 NXT1 NXT1 PABPC1L PABPC1L CSTF1 CSTF1 PPP2R3A PPP2R3A PELO PELO PPP2R5D PPP2R5D RNGTT RNGTT UPF3B UPF3B PABPC4 PABPC4 SMG1 SMG1 PABPC3 PABPC3 SMG5 SMG5 GLE1 GLE1 RNMT RNMT PABPN1L PABPN1L FUS FUS DDX39B DDX39B PABPC5 PABPC5 NXF5 NXF5 PABPC1L2A PABPC1L2A NCBP1 NCBP1 WDR82 WDR82 CLP1 CLP1 PPP2CA PPP2CA ETF1 ETF1 SYMPK SYMPK LOC100609914 LOC100609914 RNPS1 RNPS1 CSTF2 CSTF2 PPP2R2A PPP2R2A PPP1CB PPP1CB PABPC4L PABPC4L UPF1 UPF1 UPF3A UPF3A PABPC1 PABPC1 LOC736868 LOC736868 MSI1 MSI1 CK820_G0055937 CK820_G0055937 PPP1CC PPP1CC SSU72P8 SSU72P8 PPP2R2B PPP2R2B PPP2R5A PPP2R5A BCL2L2 BCL2L2 NXT2 NXT2 PPP2R1A PPP2R1A SMG7 SMG7 HBS1L HBS1L PPP2CB PPP2CB DDX19B DDX19B PYM1 PYM1 ALYREF ALYREF FIP1L1 FIP1L1 PPP2R2C PPP2R2C PAPOLB PAPOLB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TARDBPTAR DNA binding protein. (414 aa)
SRRM1SRRM1 isoform 3. (918 aa)
MAGOHMago-nashi homolog, proliferation-associated. (146 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1272 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa)
CSTF3Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa. (717 aa)
CPSF7CPSF7 isoform 1. (471 aa)
NXF1Nuclear RNA export factor 1. (619 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
PCF11PCF11, cleavage and polyadenylation factor subunit, homolog. (1686 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
SAP18Sin3A associated protein 18. (172 aa)
ACIN1ACIN1 isoform 7. (1342 aa)
PPP2R3CProtein phosphatase 2, regulatory subunit B'', gamma. (453 aa)
PNNPinin, desmosome associated protein. (719 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
GSPT1G1 to S phase transition 1. (521 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
SMG6SMG6 isoform 2. (1419 aa)
MSI2Musashi RNA binding protein 2. (324 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
CPSF3Cleavage and polyadenylation specificity factor 73 kDa subunit. (684 aa)
PAPOLGPoly(A) polymerase gamma. (736 aa)
WDR33WD repeat domain 33. (1336 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
PABPC1LPoly(A) binding protein cytoplasmic 1 like. (330 aa)
CSTF1Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa. (431 aa)
PPP2R3APPP2R3A isoform 1. (1150 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
SMG1SMG1 isoform 1; Belongs to the PI3/PI4-kinase family. (3610 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (633 aa)
SMG5Smg-5 homolog, nonsense mediated mRNA decay factor. (1016 aa)
GLE1GLE1 RNA export mediator homolog. (690 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (476 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (278 aa)
FUSFUS isoform 7. (526 aa)
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)
PABPC5Polyadenylate-binding protein 5; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). (382 aa)
NXF5NXF5 isoform 2. (397 aa)
PABPC1L2APABPC1L2A isoform 1. (200 aa)
NCBP1Nuclear cap binding protein subunit 1, 80kDa. (790 aa)
WDR82WD repeat domain 82. (313 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
PPP2CAPPP2CB isoform 8. (309 aa)
ETF1Eukaryotic translation termination factor 1. (423 aa)
SYMPKSYMPK isoform 3. (1310 aa)
LOC100609914PPP2R3B isoform 3. (475 aa)
RNPS1RNA binding protein with serine rich domain 1. (305 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
PABPC4LPABPC4L isoform 1. (430 aa)
UPF1UPF1 RNA helicase and ATPase. (1129 aa)
UPF3AUPF3A isoform 1. (476 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
LOC736868Protein mago nashi homolog. (148 aa)
MSI1Musashi RNA binding protein 1. (362 aa)
CK820_G0055937NXF2B isoform 3. (624 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
SSU72P8SSU72 pseudogene 8. (194 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
BCL2L2BCL2L2 isoform 2. (333 aa)
NXT2Nuclear transport factor 2 like export factor 2. (197 aa)
PPP2R1AProtein phosphatase 2, regulatory subunit A, alpha. (637 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1178 aa)
HBS1LHBS1 like translational GTPase. (698 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
DDX19BDEAD (Asp-Glu-Ala-As) box polypeptide 19A. (446 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (204 aa)
ALYREFAly/REF export factor. (285 aa)
FIP1L1Pre-mRNA 3'-end-processing factor FIP1 isoform X1. (603 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (469 aa)
PAPOLBPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (687 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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