(21 nodes) Protein export network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSPA5	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family. (654 aa)
	SRP9	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	IMMP1L	Mitochondrial inner membrane protease subunit. (166 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	SRP14	Signal recognition particle 14kDa (Homologous Alu RNA binding protein). (136 aa)
	SPCS1	Signal peptidase complex subunit 1. (169 aa)
	SRPRB	Signal recognition particle receptor, B subunit. (271 aa)
	SPCS3	Signal peptidase complex subunit 3. (180 aa)
	SRP19	T0134643 isoform 2. (144 aa)
	SEC63	SEC63 homolog, protein translocation regulator. (760 aa)
	SEC61G	SEC61 translocon gamma subunit. (68 aa)
	IMMP2L	Mitochondrial inner membrane protease subunit. (175 aa)
	SEC61B	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	SEC62	SEC62 homolog, preprotein translocation factor. (399 aa)
	SRPRA	Signal recognition particle receptor (Docking protein). (638 aa)
	OXA1L	OXA1L mitochondrial inner membrane protein. (435 aa)
	SEC61A2	SEC61 translocon alpha 2 subunit. (482 aa)
	SEC61A1	SEC61 translocon alpha 1 subunit. (482 aa)
	SRP72	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (672 aa)
	SEC11C	Signal peptidase complex catalytic subunit SEC11. (192 aa)
	SRP68	SRP68 isoform 2. (670 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSPA5	SEC61A1	ENSPTRP00000000984	ENSPTRP00000068673	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	SEC61 translocon alpha 1 subunit.	0.850
HSPA5	SEC61A2	ENSPTRP00000000984	ENSPTRP00000061792	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	SEC61 translocon alpha 2 subunit.	0.568
HSPA5	SEC62	ENSPTRP00000000984	ENSPTRP00000045881	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	SEC62 homolog, preprotein translocation factor.	0.486
HSPA5	SEC63	ENSPTRP00000000984	ENSPTRP00000031547	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	SEC63 homolog, protein translocation regulator.	0.822
IMMP1L	IMMP2L	ENSPTRP00000006031	ENSPTRP00000033551	Mitochondrial inner membrane protease subunit.	Mitochondrial inner membrane protease subunit.	0.661
IMMP1L	SPCS1	ENSPTRP00000006031	ENSPTRP00000025933	Mitochondrial inner membrane protease subunit.	Signal peptidase complex subunit 1.	0.737
IMMP1L	SPCS3	ENSPTRP00000006031	ENSPTRP00000028507	Mitochondrial inner membrane protease subunit.	Signal peptidase complex subunit 3.	0.728
IMMP2L	IMMP1L	ENSPTRP00000033551	ENSPTRP00000006031	Mitochondrial inner membrane protease subunit.	Mitochondrial inner membrane protease subunit.	0.661
IMMP2L	OXA1L	ENSPTRP00000033551	ENSPTRP00000052784	Mitochondrial inner membrane protease subunit.	OXA1L mitochondrial inner membrane protein.	0.427
IMMP2L	SPCS1	ENSPTRP00000033551	ENSPTRP00000025933	Mitochondrial inner membrane protease subunit.	Signal peptidase complex subunit 1.	0.737
IMMP2L	SPCS3	ENSPTRP00000033551	ENSPTRP00000028507	Mitochondrial inner membrane protease subunit.	Signal peptidase complex subunit 3.	0.728
OXA1L	IMMP2L	ENSPTRP00000052784	ENSPTRP00000033551	OXA1L mitochondrial inner membrane protein.	Mitochondrial inner membrane protease subunit.	0.427
OXA1L	SEC61A1	ENSPTRP00000052784	ENSPTRP00000068673	OXA1L mitochondrial inner membrane protein.	SEC61 translocon alpha 1 subunit.	0.802
OXA1L	SEC61A2	ENSPTRP00000052784	ENSPTRP00000061792	OXA1L mitochondrial inner membrane protein.	SEC61 translocon alpha 2 subunit.	0.797
OXA1L	SRP54	ENSPTRP00000052784	ENSPTRP00000010626	OXA1L mitochondrial inner membrane protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.473
OXA1L	SRPRA	ENSPTRP00000052784	ENSPTRP00000047565	OXA1L mitochondrial inner membrane protein.	Signal recognition particle receptor (Docking protein).	0.442
SEC11C	SEC61A1	ENSPTRP00000085560	ENSPTRP00000068673	Signal peptidase complex catalytic subunit SEC11.	SEC61 translocon alpha 1 subunit.	0.509
SEC11C	SEC61B	ENSPTRP00000085560	ENSPTRP00000036204	Signal peptidase complex catalytic subunit SEC11.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.484
SEC11C	SEC61G	ENSPTRP00000085560	ENSPTRP00000032803	Signal peptidase complex catalytic subunit SEC11.	SEC61 translocon gamma subunit.	0.613
SEC11C	SPCS1	ENSPTRP00000085560	ENSPTRP00000025933	Signal peptidase complex catalytic subunit SEC11.	Signal peptidase complex subunit 1.	0.996