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| | NPPA | Natriuretic peptide A. (153 aa) |
| | NPPB | Natriuretic peptide B. (134 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | GNAI3 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa) |
| | NPR1 | Guanylate cyclase. (1061 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3-like 4. (395 aa) |
| | ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1029 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (303 aa) |
| | RGS2 | Regulator of G-protein signaling 2, 24kDa. (211 aa) |
| | ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa) |
| | CALML5 | Calmodulin like 5. (146 aa) |
| | PRKG1 | cGMP-dependent protein kinase. (686 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa) |
| | ADRB1 | Adrenoceptor beta 1. (476 aa) |
| | MRVI1 | Murine retrovirus integration site 1 homolog. (912 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3-like 1. (519 aa) |
| | TRPC6 | Transient receptor potential cation channel, subfamily C, member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa) |
| | KCNJ8 | Potassium inwardly-rectifying channel, subfamily J, member 8. (424 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa) |
| | IRS2 | IRS2 isoform 1. (1340 aa) |
| | ADCY4 | Adenylate cyclase type 4 isoform X1. (1077 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | MYLK3 | MYLK3 isoform 1. (819 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (882 aa) |
| | GNA13 | Guanine nucleotide binding protein (G protein), alpha 13. (377 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (461 aa) |
| | MEF2B | MADS-box transcription enhancer factor 2B. (368 aa) |
| | CALM3 | Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | NPPC | Natriuretic peptide C. (126 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | MYLK2 | MYLK2 isoform 1. (596 aa) |
| | MYL9 | Myosin, light chain 9, regulatory. (172 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | ATF4 | Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa) |
| | ITPR1 | ITPR1 isoform 3. (2700 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | GNAI2 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (355 aa) |
| | ADCY5 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa) |
| | CNGA1-2 | Cyclic nucleotide gated channel subunit alpha 1. (759 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa) |
| | ADRB2 | Adrenergic, beta-2-, receptor, surface. (429 aa) |
| | KCNMB1 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa) |
| | MYLK4 | Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa) |
| | ITPR3 | ITPR3 isoform 1. (2677 aa) |
| | SRF | Serum response factor (C-fos serum response element-binding transcription factor). (508 aa) |
| | GNA12 | Guanine nucleotide binding protein (G protein) alpha 12. (381 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa) |
| | GTF2I | General transcription factor IIi. (998 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3-like 2. (520 aa) |
| | NPR2 | Guanylate cyclase. (1047 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa) |
| | ADRB3 | ADRB3 isoform 1. (408 aa) |
| | PDE5A | Phosphodiesterase. (875 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa) |
| | PDE3A | Phosphodiesterase. (1141 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (1030 aa) |
| | NFATC2 | NFATC2 isoform 4. (938 aa) |
| | PDE2A | Phosphodiesterase. (941 aa) |
| | GNAQ | Guanine nucleotide binding protein (G protein), q polypeptide. (359 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (371 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | KCNU1 | Potassium calcium-activated channel subfamily U member 1. (1149 aa) |
| | ATF6B | Activating transcription factor 6 beta. (711 aa) |
| | ADRA2C | Adrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | SLC25A5 | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | ADRA2B | Adrenoceptor alpha 2B. (448 aa) |
| | ADRA2A | Adrenergic, alpha-2A-, receptor. (465 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1286 aa) |
| | GTF2IRD1 | GTF2I repeat domain containing 1. (960 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa) |
| | SLC25A6 | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | PRKG2 | cGMP-dependent protein kinase. (762 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1408 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (644 aa) |
| | LOC452727 | Guanylate cyclase soluble subunit beta-2. (664 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (526 aa) |
| | KNG1 | KNG1 isoform 2. (644 aa) |
| | ATP1B4 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | KCNMB3 | Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (279 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa) |
| | ATP1A3 | ATP1A3 isoform 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1287 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | GNAI1 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. (422 aa) |
| | KCNMB4 | Potassium large conductance calcium-activated channel, subfamily M, beta member 4. (210 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | MEF2D | Myocyte enhancer factor 2D. (521 aa) |
| | GNA11 | Guanine nucleotide binding protein (G protein), alpha 11 (Gq class). (359 aa) |
| | GUCY1A2 | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (765 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (521 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa) |
| | GATA4 | GATA binding protein 4. (443 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | CREB5 | CREB5 isoform 1. (508 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | IRS4 | Insulin receptor substrate 4. (1257 aa) |
| | MYH7 | Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1068 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | VDAC2 | VDAC2 isoform 1. (260 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (495 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] (1368 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | VDAC1 | Voltage-dependent anion channel 1. (289 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa) |
| | BDKRB2 | B2 bradykinin receptor isoform X1. (391 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (933 aa) |
| | MYLK | MYLK isoform 12. (1919 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | SLC25A4 | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1027 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) |
| | VASP | Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa) |
| | KCNMB2 | Potassium calcium-activated channel subfamily M regulatory beta subunit 2. (263 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
