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| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | LPAR3 | Lysophosphatidic acid receptor 3. (353 aa) |
| | NRAS | Neuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa) |
| | FCER1A | FCER1A isoform 1. (260 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | ARF1 | ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa) |
| | HRAS | V-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa) |
| | RRAS2 | Related RAS viral (R-ras) oncogene homolog 2. (204 aa) |
| | DGKZ | Diacylglycerol kinase. (1117 aa) |
| | F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa) |
| | MS4A2 | Membrane spanning 4-domains A2. (244 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1210 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | LPAR6 | Lysophosphatidic acid receptor 6. (345 aa) |
| | ADCY4 | Adenylate cyclase type 4 isoform X1. (1077 aa) |
| | PLA2G4E | Phospholipase A2. (868 aa) |
| | PLA2G4D | Phospholipase A2. (818 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | PLD2 | Phospholipase. (933 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (882 aa) |
| | DGKE | Diacylglycerol kinase. (567 aa) |
| | GNA13 | Guanine nucleotide binding protein (G protein), alpha 13. (377 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | PLPP2 | PLPP2 isoform 5. (309 aa) |
| | PIP5K1C | Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa) |
| | SPHK2 | Sphingosine kinase 2. (255 aa) |
| | RRAS | Related RAS viral (R-ras) oncogene homolog. (218 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | CXCR1 | C-X-C chemokine receptor type 1; Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. (350 aa) |
| | DGKD | Diacylglycerol kinase. (1254 aa) |
| | AVP | Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | GRM7 | Glutamate metabotropic receptor 7. (922 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | ADCY5 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | DGKG | Diacylglycerol kinase. (791 aa) |
| | PDGFRA | T0011027 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1102 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) |
| | GAB1 | GRB2-associated-binding protein 1. (724 aa) |
| | PLPP1 | Phospholipid phosphatase 1. (285 aa) |
| | F2R | Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | GRM6 | GRM6 isoform 2. (879 aa) |
| | GRM1 | Glutamate receptor, metabotropic 1. (1194 aa) |
| | GNA12 | Guanine nucleotide binding protein (G protein) alpha 12. (381 aa) |
| | CYTH3 | CYTH3 isoform 1. (399 aa) |
| | RALA | V-ral simian leukemia viral oncogene homolog A (Ras related). (206 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa) |
| | GRM3 | Glutamate metabotropic receptor 3. (879 aa) |
| | AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 (Lysophosphatidic acid acyltransferase, epsilon). (364 aa) |
| | PTK2B | PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | RALGDS | Ral guanine nucleotide dissociation stimulator. (914 aa) |
| | LPAR4 | Lysophosphatidic acid receptor 4. (370 aa) |
| | LPAR2 | Lysophosphatidic acid receptor 2. (351 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | GAB2 | GRB2-associated-binding protein 2. (676 aa) |
| | DNM3 | DNM3 isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa) |
| | AGPAT2 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (279 aa) |
| | GRM2 | Glutamate metabotropic receptor 2. (872 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (112 aa) |
| | SHC1 | SHC (Src homology 2 domain containing) transforming protein 1. (584 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | PTGFR | Prostaglandin F receptor (FP); Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | AVPR2 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa) |
| | DGKB | Diacylglycerol kinase. (803 aa) |
| | PDGFA | PDGFA isoform 4; Belongs to the PDGF/VEGF growth factor family. (227 aa) |
| | GNAS | GNAS isoform 19. (1042 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5. (372 aa) |
| | LOC749464 | Phospholipase A2. (781 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) |
| | RAPGEF4 | RAPGEF4 isoform 2. (1011 aa) |
| | CYTH4 | CYTH4 isoform 2. (397 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa) |
| | LOC104003639 | Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1408 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | SHC3 | SHC3 isoform 2. (598 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa) |
| | ARF6 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (575 aa) |
| | GRM4 | Glutamate receptor, metabotropic 4. (912 aa) |
| | AGPAT1 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (288 aa) |
| | DNM2 | DNM2 isoform 5; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) |
| | PIP5K1A | Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa) |
| | RALB | V-ral simian leukemia viral oncogene homolog B (Ras related GTP binding protein). (212 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | CXCR2 | C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2 (By similarity). (360 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa) |
| | DGKH | Diacylglycerol kinase. (1220 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | DGKK | Diacylglycerol kinase. (1283 aa) |
| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | PLPP3 | T0036865 isoform 1. (342 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | CYTH1 | CYTH1 isoform 3. (399 aa) |
| | AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3. (376 aa) |
| | AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 (Lysophosphatidic acid acyltransferase, delta). (378 aa) |
| | DGKQ | Diacylglycerol kinase. (952 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | GRM8 | Glutamate metabotropic receptor 8. (908 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | DNM1 | DNM1 isoform 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa) |
| | KRAS | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | RHEB | RHEB isoform 1. (184 aa) |
| | DGKA | Diacylglycerol kinase. (746 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
