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| | GNAI3 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3-like 4. (395 aa) |
| | ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1029 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (303 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa) |
| | CALML5 | Calmodulin like 5. (146 aa) |
| | ADRB1 | Adrenoceptor beta 1. (476 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3-like 1. (519 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa) |
| | RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) |
| | PPP1R1A | Protein phosphatase 1 regulatory inhibitor subunit 1A. (171 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | ADCY4 | Adenylate cyclase type 4 isoform X1. (1077 aa) |
| | PPP2R3C | Protein phosphatase 2, regulatory subunit B'', gamma. (453 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | ACTC1 | Actin alpha cardiac muscle 1. (377 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | CACNG3 | Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (882 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | CACNG5 | Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa) |
| | CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (461 aa) |
| | PRKACA | PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa) |
| | CALM3 | Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | KCNE1 | KCNE1B isoform 1. (132 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | ATF4 | Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa) |
| | MYL3 | Myosin, light chain 3, alkali ventricular, skeletal, slow. (224 aa) |
| | GNAI2 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (355 aa) |
| | TNNC1 | Troponin C1, slow skeletal and cardiac type. (161 aa) |
| | ADCY5 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa) |
| | PPP2R3A | PPP2R3A isoform 1. (1150 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa) |
| | ADRB2 | Adrenergic, beta-2-, receptor, surface. (429 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3-like 2. (520 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa) |
| | TPM1 | TPM1 isoform 3; Belongs to the tropomyosin family. (326 aa) |
| | SCN7A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1682 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | CACNB2 | Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa) |
| | MYL4 | Myosin, light chain 4, alkali atrial, embryonic. (193 aa) |
| | TNNI3 | TNNI3 isoform 2. (169 aa) |
| | GNAQ | Guanine nucleotide binding protein (G protein), q polypeptide. (359 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (371 aa) |
| | CACNA2D3 | CACNA2D3 isoform 3. (1091 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (370 aa) |
| | CACNB4 | Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa) |
| | ATF6B | Activating transcription factor 6 beta. (711 aa) |
| | GNAS | GNAS isoform 19. (1042 aa) |
| | RAPGEF4 | RAPGEF4 isoform 2. (1011 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa) |
| | LOC104003639 | Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | PPP2CA | PPP2CB isoform 8. (309 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | RYR2 | RYR2 isoform 1. (4941 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | ATP1B4 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa) |
| | LOC100609914 | PPP2R3B isoform 3. (475 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa) |
| | ATP1A3 | ATP1A3 isoform 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1287 aa) |
| | LOC101058464 | TPM3 isoform 13; Belongs to the tropomyosin family. (245 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa) |
| | TPM2 | TPM2 isoform 3; Belongs to the tropomyosin family. (284 aa) |
| | TNNT2 | Troponin T type 2 (Cardiac). (298 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa) |
| | GNAI1 | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. (422 aa) |
| | CACNA2D4 | CACNA2D4 isoform 6. (1154 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (666 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | CREB5 | CREB5 isoform 1. (508 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa) |
| | MYL2 | Myosin, light chain 2, regulatory, cardiac, slow. (166 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) |
| | MYH7 | Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1068 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | PPP2R1A | Protein phosphatase 2, regulatory subunit A, alpha. (637 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (495 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa) |
| | CACNB3 | Calcium channel, voltage-dependent, beta 3 subunit. (487 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | SCN1B | Sodium channel subunit beta-1; Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A. (268 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1027 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (469 aa) |
| | SCN4B | Sodium voltage-gated channel beta subunit 4. (228 aa) |
| | LOC460237 | TPM4 isoform 1; Belongs to the tropomyosin family. (241 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
