STRINGSTRING
WASF2 WASF2 ENSPTRP00000000715 ENSPTRP00000000715 TMSB4X-2 TMSB4X-2 NRAS NRAS ITGA10 ITGA10 ARPC5 ARPC5 CHRM3 CHRM3 DOCK1 DOCK1 HRAS HRAS RRAS2 RRAS2 F2 F2 CHRM1 CHRM1 FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 PAK1 PAK1 FGF23 FGF23 ITGA5 ITGA5 NCKAP1L NCKAP1L ITGA7 ITGA7 FGF9 FGF9 CFL2 CFL2 CYFIP1 CYFIP1 CHRM5 CHRM5 PAK6 PAK6 FGF7 FGF7 IQGAP1 IQGAP1 MYLPF MYLPF ITGAM ITGAM ITGAD ITGAD MYLK3 MYLK3 PFN1 PFN1 SSH2 SSH2 PIP4K2B PIP4K2B ITGA3 ITGA3 GNA13 GNA13 MYL12B MYL12B PIP5K1C PIP5K1C MAP2K2 MAP2K2 VAV1 VAV1 PIK3R2 PIK3R2 ARHGEF1 ARHGEF1 FGF21 FGF21 RRAS RRAS PFN4 PFN4 ARHGEF4 ARHGEF4 ITGA4 ITGA4 NCKAP1 NCKAP1 PIKFYVE PIKFYVE PAK5 PAK5 MYLK2 MYLK2 MYL9 MYL9 TIAM1 TIAM1 MAPK1 MAPK1 PDGFB PDGFB BRK1 BRK1 ITGA9 ITGA9 RHOA RHOA MRAS MRAS PIK3CB PIK3CB PFN2 PFN2 PDGFRA PDGFRA EGF EGF ITGA1 ITGA1 F2R F2R APC APC FGF1 FGF1 FGFR4 FGFR4 MYLK4 MYLK4 GNA12 GNA12 ARPC1A ARPC1A ARPC1B ARPC1B WASL WASL MOS MOS GSN GSN ARPC5L ARPC5L FGD1 FGD1 LPAR4 LPAR4 LPAR2 LPAR2 FGF17 FGF17 ARHGEF6 ARHGEF6 SOS2 SOS2 FGF16 FGF16 WASF1 WASF1 CRKL CRKL PPP1R12A PPP1R12A ITGAV ITGAV LIMK2 LIMK2 ITGB5 ITGB5 IQGAP3 IQGAP3 SOS1 SOS1 ITGAL ITGAL MAPK3 MAPK3 ARHGEF12 ARHGEF12 ACTB ACTB PDGFA PDGFA GIT1 GIT1 CHRM4 CHRM4 LPAR5 LPAR5 GNG12 GNG12 PAK3 PAK3 FGD3 FGD3 PFN3 PFN3 MAP2K1 MAP2K1 LPAR1 LPAR1 ROCK2 ROCK2 PIK3R3 PIK3R3 MYH11 MYH11 MYL12A MYL12A CYFIP2 CYFIP2 MYH14 MYH14 KNG1 KNG1 FGF22 FGF22 FGFR1 FGFR1 DIAPH3 DIAPH3 SLC9A1 SLC9A1 FGF2 FGF2 CXCL12 CXCL12 ITGB3 ITGB3 PPP1CB PPP1CB MYH10 MYH10 EGFR EGFR ITGB1 ITGB1 PIP5K1B PIP5K1B DIAPH2 DIAPH2 INSRR INSRR PIP4K2A PIP4K2A RDX RDX ABI2 ABI2 PIP5K1A PIP5K1A CXCR4 CXCR4 ARPC3 ARPC3 ITGB7 ITGB7 ARHGAP35 ARHGAP35 FGF8 FGF8 DIAPH1 DIAPH1 SRC SRC PIK3R1 PIK3R1 MYL10-2 MYL10-2 CDC42 CDC42 PPP1CC PPP1CC PDGFD PDGFD ITGAX ITGAX MYH9 MYH9 LIMK1-2 LIMK1-2 BRAF BRAF SSH3 SSH3 BCAR1 BCAR1 MYL2 MYL2 PPP1R12B PPP1R12B PDGFRB PDGFRB ACTN4 ACTN4 ITGB4 ITGB4 ITGA2 ITGA2 ITGB8 ITGB8 CRK CRK FGF10 FGF10 ARAF ARAF VAV2 VAV2 ITGA11 ITGA11 ARPC4 ARPC4 KRAS KRAS ROCK1 ROCK1 FGF6 FGF6 ITGA8 ITGA8 FGF20 FGF20 CHRM2 CHRM2 BDKRB2 BDKRB2 MSN MSN CFL1 CFL1 SPATA13 SPATA13 IQGAP2 IQGAP2 ITGA6 ITGA6 ITGAE ITGAE APC2 APC2 FGFR3 FGFR3 MYLK MYLK ARPC2 ARPC2 PAK4 PAK4 VAV3 VAV3 SSH1 SSH1 PIP4K2C PIP4K2C PDGFC PDGFC ITGB2 ITGB2 FGF18 FGF18 SCIN-2 SCIN-2 MYL5 MYL5 PPP1R12C PPP1R12C EZR EZR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WASF2WAS protein family, member 2. (498 aa)
ENSPTRP00000000715Wiskott-Aldrich syndrome protein family member 2-like. (492 aa)
TMSB4X-2Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
ITGA10ITGA10 isoform 1; Belongs to the integrin alpha chain family. (1167 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CHRM3Muscarinic acetylcholine receptor M3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). (590 aa)
DOCK1DOCK1 isoform 1; Belongs to the DOCK family. (1854 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
RRAS2Related RAS viral (R-ras) oncogene homolog 2. (204 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
PAK1Non-specific serine/threonine protein kinase. (553 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
ITGA5ITGA5 isoform 2; Belongs to the integrin alpha chain family. (1098 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
ITGA7ITGA7 isoform 6; Belongs to the integrin alpha chain family. (1181 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CFL2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
CHRM5Muscarinic acetylcholine receptor M5; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. (532 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (169 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
ITGADITGAD isoform 1; Belongs to the integrin alpha chain family. (1161 aa)
MYLK3MYLK3 isoform 1. (819 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
SSH2Slingshot protein phosphatase 2. (1450 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase, type II, beta. (416 aa)
ITGA3ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa)
GNA13Guanine nucleotide binding protein (G protein), alpha 13. (377 aa)
MYL12BMyosin light chain 12B. (172 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
RRASRelated RAS viral (R-ras) oncogene homolog. (218 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (1876 aa)
ITGA4Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor); Belongs to the integrin alpha chain family. (1032 aa)
NCKAP1Nck-associated protein 1. (1128 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
MYLK2MYLK2 isoform 1. (596 aa)
MYL9Myosin, light chain 9, regulatory. (172 aa)
TIAM1T-cell lymphoma invasion and metastasis 1. (1591 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
RHOARas homolog family member A. (193 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
PDGFRAT0011027 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1102 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
F2RCoagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
APCAdenomatous polyposis coli protein isoform X10. (2844 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
GNA12Guanine nucleotide binding protein (G protein) alpha 12. (381 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin related protein 2/3 complex, subunit 1A/1B. (372 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa)
GSNGSN isoform 3. (782 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (961 aa)
LPAR4Lysophosphatidic acid receptor 4. (370 aa)
LPAR2Lysophosphatidic acid receptor 2. (351 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (783 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
WASF1Wiskott-Aldrich syndrome protein family member 1. (559 aa)
CRKLV-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
ITGAVIntegrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa)
LIMK2LIMK2 isoform 6. (670 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1589 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
ITGALITGAL isoform 4. (344 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 12. (1544 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
PDGFAPDGFA isoform 4; Belongs to the PDGF/VEGF growth factor family. (227 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
LPAR5Lysophosphatidic acid receptor 5. (372 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PAK3Serine/threonine-protein kinase PAK 3; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstrea [...] (580 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (725 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
PIK3R3Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa)
MYH11MYH11 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
MYL12AMyosin light chain 12A. (177 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
KNG1KNG1 isoform 2. (644 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
FGFR1Fibroblast growth factor receptor. (854 aa)
DIAPH3Diaphanous related formin 3. (1193 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
ITGB3Integrin beta-3 isoform X2. (837 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (575 aa)
DIAPH2DIAPH2 isoform 3. (1103 aa)
INSRRTyrosine-protein kinase receptor. (1297 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase, type II, alpha. (406 aa)
RDXRDX isoform 3. (609 aa)
ABI2Abl interactor 2. (513 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (423 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (802 aa)
ARHGAP35Glucocorticoid receptor DNA binding factor 1. (1519 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
DIAPH1DIAPH1 isoform 4. (1278 aa)
SRCTyrosine-protein kinase. (542 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
MYL10-2MYL10 isoform 1. (226 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
PDGFDPlatelet derived growth factor D. (370 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
LIMK1-2LIM domain kinase 1. (677 aa)
BRAFBRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
SSH3Slingshot protein phosphatase 3. (658 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1043 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ACTN4Actinin, alpha 4. (931 aa)
ITGB4Integrin beta. (1822 aa)
ITGA2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (780 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ARAFV-raf murine sarcoma 3611 viral oncogene homolog. (606 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1206 aa)
ARPC4Actin-related protein 2/3 complex subunit 4 isoform X4. (173 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
ROCK1Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] (1368 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
CHRM2Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...] (466 aa)
BDKRB2B2 bradykinin receptor isoform X1. (391 aa)
MSNMSN isoform 1. (577 aa)
CFL1CFL1 isoform 2; Belongs to the actin-binding proteins ADF family. (204 aa)
SPATA13Spermatogenesis-associated protein 13 isoform X4. (1279 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1600 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ITGAEITGAE isoform 1; Belongs to the integrin alpha chain family. (1180 aa)
APC2APC2 isoform 1. (2301 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
MYLKMYLK isoform 12. (1919 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
VAV3VAV3 isoform 2. (927 aa)
SSH1Slingshot homolog 1. (1062 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase, type II, gamma. (421 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
ITGB2Integrin beta. (863 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SCIN-2SCIN isoform 2. (715 aa)
MYL5Myosin light chain 5. (173 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit. (793 aa)
EZREZR isoform 1. (671 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (34%) [HD]