Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE | ADRB1 | ENSPTRP00000038991 | ENSPTRP00000005222 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Adrenoceptor beta 1. | 0.485 |
| ACE | ADRB2 | ENSPTRP00000038991 | ENSPTRP00000029722 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Adrenergic, beta-2-, receptor, surface. | 0.436 |
| ACE | AGT | ENSPTRP00000038991 | ENSPTRP00000003543 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. | 0.990 |
| ACE | AGTR1 | ENSPTRP00000038991 | ENSPTRP00000063456 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.841 |
| ACE | CALM3 | ENSPTRP00000038991 | ENSPTRP00000019197 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. | 0.527 |
| ACE | CALML3 | ENSPTRP00000038991 | ENSPTRP00000064433 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Calmodulin like 3; Belongs to the calmodulin family. | 0.595 |
| ACE | CALML5 | ENSPTRP00000038991 | ENSPTRP00000003820 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Calmodulin like 5. | 0.595 |
| ACE | CALML6 | ENSPTRP00000038991 | ENSPTRP00000043977 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Calmodulin like 6. | 0.585 |
| ACE | EDN1 | ENSPTRP00000038991 | ENSPTRP00000030273 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | EDN1 isoform 1. | 0.639 |
| ACE | NPPA | ENSPTRP00000038991 | ENSPTRP00000000299 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Natriuretic peptide A. | 0.661 |
| ACE | REN | ENSPTRP00000038991 | ENSPTRP00000051292 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.910 |
| ADCY5 | ADCY6 | ENSPTRP00000026385 | ENSPTRP00000093557 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.957 |
| ADCY5 | ADRB1 | ENSPTRP00000026385 | ENSPTRP00000005222 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adrenoceptor beta 1. | 0.525 |
| ADCY5 | ADRB2 | ENSPTRP00000026385 | ENSPTRP00000029722 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adrenergic, beta-2-, receptor, surface. | 0.446 |
| ADCY5 | CACNA1C | ENSPTRP00000026385 | ENSPTRP00000007742 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.632 |
| ADCY5 | CALM3 | ENSPTRP00000026385 | ENSPTRP00000019197 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. | 0.777 |
| ADCY5 | CALML3 | ENSPTRP00000026385 | ENSPTRP00000064433 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Calmodulin like 3; Belongs to the calmodulin family. | 0.787 |
| ADCY5 | CALML5 | ENSPTRP00000026385 | ENSPTRP00000003820 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Calmodulin like 5. | 0.788 |
| ADCY5 | CALML6 | ENSPTRP00000026385 | ENSPTRP00000043977 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Calmodulin like 6. | 0.786 |
| ADCY5 | GNAI1 | ENSPTRP00000026385 | ENSPTRP00000071974 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | 0.946 |
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