STRINGSTRING
E2F2 E2F2 CDC20 CDC20 CDKN2C CDKN2C JAK1 JAK1 NRAS NRAS CREB3L4 CREB3L4 FDPS FDPS ELK4 ELK4 TGFB2 TGFB2 IL2RA IL2RA NRP1 NRP1 EGR2 EGR2 HRAS HRAS CREB3L1 CREB3L1 KAT5 KAT5 FOSL1 FOSL1 MMP7 MMP7 CD3E CD3E CD3G CD3G CCND2 CCND2 LTBR LTBR ESPL1 ESPL1 ANAPC5 ANAPC5 RB1 RB1 ADCY4 ADCY4 NFKBIA NFKBIA TBPL2 TBPL2 TGFB3 TGFB3 B2M B2M CCNB2 CCNB2 TLN2 TLN2 ADCY9 ADCY9 VAC14 VAC14 GPS2 GPS2 TP53 TP53 MAP2K4 MAP2K4 KAT2A KAT2A MAP3K3 MAP3K3 SMAD4 SMAD4 MAP2K2 MAP2K2 CREB3L3 CREB3L3 CALR CALR PRKACA PRKACA PIK3R2 PIK3R2 CRTC1 CRTC1 ZFP36 ZFP36 TGFB1 TGFB1 ADCY3 ADCY3 IL1R2 IL1R2 BCL2L1 BCL2L1 E2F1 E2F1 RANBP1-2 RANBP1-2 MAPK1 MAPK1 IL2RB IL2RB ATF4 ATF4 EP300 EP300 TNFRSF13C TNFRSF13C KAT2B KAT2B ADCY5 ADCY5 PIK3CB PIK3CB ANAPC4 ANAPC4 NFKB1 NFKB1 MAD2L1 MAD2L1 CCNA2 CCNA2 IL2 IL2 SLC25A31 SLC25A31 TERT-2 TERT-2 CSF2 CSF2 CDC23 CDC23 PTTG1 PTTG1 MSX2 MSX2 CANX CANX MAPK9 MAPK9 LTA LTA PATR-DRA PATR-DRA HLA-DQB1 HLA-DQB1 PATR-DOB PATR-DOB PATR-DMB PATR-DMB MAMU-DMA MAMU-DMA HLA-DOA HLA-DOA HLA-DPA1 HLA-DPA1 SRF SRF TBPL1 TBPL1 ADCY1 ADCY1 CREB3L2 CREB3L2 IKBKB IKBKB POLB POLB PRKACG PRKACG CDC26 CDC26 ANAPC2 ANAPC2 ELK1 ELK1 CDK4 CDK4 MAPK8 MAPK8 XPO1 XPO1 TSPO TSPO PRKACB PRKACB ETS2 ETS2 CRTC3 CRTC3 TRRAP TRRAP NFATC2 NFATC2 IL2RG IL2RG MAP3K1 MAP3K1 CREB3 CREB3 ATR ATR ITGAL ITGAL CCNE2 CCNE2 MAPK3 MAPK3 ATM ATM RELA RELA LOC104006793 LOC104006793 PATR-F PATR-F CD4 CD4 HLA-DQA1 HLA-DQA1 MSX1 MSX1 PATR-G PATR-G MAP3K14 MAP3K14 HLA-DPB1 HLA-DPB1 MAD1L1 MAD1L1 ATF6B ATF6B TBP TBP PATR-DQB1 PATR-DQB1 CDKN1A CDKN1A SLC25A5 SLC25A5 SMAD2 SMAD2 CDC16 CDC16 ADCY7 ADCY7 SLC25A6 SLC25A6 MAP2K1 MAP2K1 ATF2 ATF2 PIK3R3 PIK3R3 PPP3CB PPP3CB PATR-B PATR-B TNFRSF1A TNFRSF1A NFKB2 NFKB2 DLG1 DLG1 ENSPTRP00000066786 ENSPTRP00000066786 CHEK1 CHEK1 E2F3 E2F3 CHEK2 CHEK2 PPP3CA PPP3CA IL15 IL15 IL6 IL6 CD40 CD40 PATR-AL PATR-AL ANAPC10 ANAPC10 CCND3 CCND3 MAPK10 MAPK10 CCNA1 CCNA1 TLN1 TLN1 ANAPC1 ANAPC1 XIAP XIAP LOC748658 LOC748658 CREB1 CREB1 TGFBR1 TGFBR1 PPP3CC PPP3CC VDAC3 VDAC3 IL15RA IL15RA CREBBP CREBBP IL1R1 IL1R1 MYC MYC LOC100610002 LOC100610002 PIK3R1 PIK3R1 ADCY8 ADCY8 CREB5 CREB5 BUB1B BUB1B SLC2A1 SLC2A1 FOS FOS RAN RAN BV7-9 BV7-9 CDC27 CDC27 AKT1 AKT1 CDKN2B CDKN2B VDAC2 VDAC2 ADCY2 ADCY2 RANBP3 RANBP3 SPI1 SPI1 ICAM1 ICAM1 CHUK CHUK KRAS KRAS EGR1 EGR1 VDAC1 VDAC1 AKT3 AKT3 CCND1 CCND1 BUB3 BUB3 ETS1 ETS1 NFATC3 NFATC3 CCNE1 CCNE1 RELB RELB NFATC4 NFATC4 AKT2 AKT2 SLC25A4 SLC25A4 ITGB2 ITGB2 PTTG2 PTTG2 BAX BAX NFYB NFYB PATR-E PATR-E ADCY6 ADCY6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E2F2E2F transcription factor 2. (437 aa)
CDC20Cell division cycle 20 homolog. (499 aa)
CDKN2CCyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4). (168 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
CREB3L4cAMP responsive element binding protein 3-like 4. (395 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (419 aa)
ELK4ELK4, ETS-domain protein (SRF accessory protein 1). (431 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
IL2RAInterleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (272 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
EGR2Early growth response 2. (476 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
CREB3L1cAMP responsive element binding protein 3-like 1. (519 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
MMP7Matrix metallopeptidase 7. (267 aa)
CD3ECD3E isoform 2. (207 aa)
CD3GCD3G isoform 1. (182 aa)
CCND2CCND2 isoform 1; Belongs to the cyclin family. (289 aa)
LTBRLymphotoxin beta receptor (TNFR superfamily, member 3). (435 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2118 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
RB1RB transcriptional corepressor 1. (928 aa)
ADCY4Adenylate cyclase type 4 isoform X1. (1077 aa)
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha. (317 aa)
TBPL2TATA box-binding protein-like protein 2; Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity). (375 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (96 aa)
CCNB2CCNB2 isoform 1; Belongs to the cyclin family. (398 aa)
TLN2TLN2 isoform 1. (2544 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
VAC14VAC14 component of PIKFYVE complex. (782 aa)
GPS2G protein pathway suppressor 2. (327 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (461 aa)
CALRCalreticulin. (414 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
CRTC1CRTC1 isoform 1. (648 aa)
ZFP36Zinc finger protein 36, C3H type, homolog. (332 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
IL1R2Interleukin 1 receptor type 2. (398 aa)
BCL2L1BCL2L1 isoform 6. (233 aa)
E2F1E2F transcription factor 1. (437 aa)
RANBP1-2RANBP1 isoform 4. (200 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
IL2RBInterleukin-2 receptor subunit beta; Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). (551 aa)
ATF4Activating transcription factor 4 (Tax-responsive enhancer element B67). (351 aa)
EP300E1A binding protein p300. (2175 aa)
TNFRSF13CTNF receptor superfamily member 13C. (184 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
NFKB1Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (969 aa)
MAD2L1MAD2 mitotic arrest deficient-like 1. (205 aa)
CCNA2CCNA2 isoform 1; Belongs to the cyclin family. (432 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
TERT-2Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (762 aa)
CSF2Colony stimulating factor 2. (144 aa)
CDC23Cell division cycle 23 homolog. (597 aa)
PTTG1Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] (202 aa)
MSX2Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity); Belongs to the Msh homeobox family. (267 aa)
CANXCANX isoform 1. (592 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LTALymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity). (205 aa)
PATR-DRAMHC class II protein; Belongs to the MHC class II family. (254 aa)
HLA-DQB1HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3. (261 aa)
PATR-DOBPatr class II histocompatibility antigen, DO beta chain; Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B- cells. Modifies peptide exchange activity of HLA-DM. (273 aa)
PATR-DMBHLA-DMB isoform 5. (263 aa)
MAMU-DMAHLA class II histocompatibility antigen, DM alpha chain isoform X1. (290 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
CREB3L2cAMP responsive element binding protein 3-like 2. (520 aa)
IKBKBInhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (763 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
CDC26Cell division cycle 26 homolog. (85 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
ELK1ELK1, member of ETS oncogene family. (428 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
XPO1XPO1 isoform 1. (1071 aa)
TSPOTranslocator protein. (169 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
CRTC3CREB regulated transcription coactivator 3. (619 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
NFATC2NFATC2 isoform 4. (938 aa)
IL2RGIL2RG isoform 1. (369 aa)
MAP3K1MAP3K1 isoform 1. (1509 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
ATRAtaxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. (2644 aa)
ITGALITGAL isoform 4. (344 aa)
CCNE2CCNE2 isoform 1; Belongs to the cyclin family. (404 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
LOC104006793HLA class II histocompatibility antigen, DR beta 3 chain precursor. (289 aa)
PATR-FPatr class I histocompatibility antigen, CH28 alpha chain; Involved in the presentation of foreign antigens to the immune system. (442 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
HLA-DQA1HLA-DQA2 isoform 1; Belongs to the MHC class II family. (255 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
PATR-GPatr class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system. (371 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
MAD1L1MAD1 mitotic arrest deficient-like 1. (718 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
TBPTBP isoform 1. (336 aa)
PATR-DQB1HLA-DRB1 isoform 1. (271 aa)
CDKN1ACyclin-dependent kinase inhibitor 1A (P21, Cip1). (276 aa)
SLC25A5Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CDC16Cell division cycle 16 homolog. (620 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PIK3R3Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa)
PPP3CBSerine/threonine-protein phosphatase. (526 aa)
PATR-BPatr class I histocompatibility antigen, C alpha chain; Involved in the presentation of foreign antigens to the immune system. (397 aa)
TNFRSF1ATumor necrosis factor receptor superfamily, member 1A. (455 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
ENSPTRP00000066786LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-3 alpha chain. (191 aa)
CHEK1CHEK1 isoform 10. (485 aa)
E2F3E2F transcription factor 3. (465 aa)
CHEK2Checkpoint kinase 2. (586 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
CD40CD40 molecule, TNF receptor superfamily member 5. (277 aa)
PATR-ALMajor histocompatibility complex, class I, AL precursor. (365 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CCND3CCND3 isoform 1; Belongs to the cyclin family. (292 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
CCNA1CCNA1 isoform 3; Belongs to the cyclin family. (421 aa)
TLN1TLN1 isoform 1. (2558 aa)
ANAPC1ANAPC1 isoform 2. (1944 aa)
XIAPBaculoviral IAP repeat-containing protein 8; Protects against apoptosis mediated by BAX. (497 aa)
LOC748658LOW QUALITY PROTEIN: homeobox protein MSX-2-like. (312 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
PPP3CCSerine/threonine-protein phosphatase. (521 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
IL15RAIL15RA isoform 11. (353 aa)
CREBBPCREB binding protein. (2442 aa)
IL1R1Interleukin 1 receptor, type I. (569 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa)
LOC100610002IKBKG isoform 9. (401 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CREB5CREB5 isoform 1. (508 aa)
BUB1BBUB1B-PAK6 isoform 4. (1068 aa)
SLC2A1Solute carrier family 2 (Facilitated glucose transporter), member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (234 aa)
BV7-9TRBV7-9 isoform 1. (155 aa)
CDC27Cell division cycle 27 homolog. (832 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
CDKN2BCyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). (138 aa)
VDAC2VDAC2 isoform 1. (260 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
RANBP3RAN binding protein 3. (562 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
ICAM1Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (537 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (760 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
VDAC1Voltage-dependent anion channel 1. (289 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
BUB3Budding uninhibited by benzimidazoles 3 homolog. (328 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3. (1075 aa)
CCNE1CCNE1 isoform 1; Belongs to the cyclin family. (411 aa)
RELBRELB isoform 3. (567 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SLC25A4Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ITGB2Integrin beta. (863 aa)
PTTG2PTTG2 isoform 1. (196 aa)
BAXBAX isoform 7. (123 aa)
NFYBNuclear transcription factor Y subunit beta. (208 aa)
PATR-EPatr class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules. (360 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (22%) [HD]