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| | EGLN1 | Egl-9 family hypoxia inducible factor 1. (426 aa) |
| | RXRG | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). (462 aa) |
| | RORC | Nuclear receptor ROR-gamma; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respective [...] (642 aa) |
| | ARNT | ARNT isoform 1. (789 aa) |
| | CIART | CIART isoform 3. (284 aa) |
| | SLC16A4 | SLC16A4 isoform 3. (452 aa) |
| | PER3 | PER3 isoform 5. (1166 aa) |
| | HIF1AN | Hypoxia inducible factor 1 subunit alpha inhibitor. (349 aa) |
| | NPAS4 | Neuronal PAS domain protein 4. (802 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (447 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (593 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] (583 aa) |
| | PGR | PGR isoform 1. (935 aa) |
| | BHLHE41 | BHLHE41 isoform 1. (265 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator like 2. (636 aa) |
| | RARG | RARG isoform 5. (469 aa) |
| | ENSPPYP00000005310 | annotation not available (135 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (586 aa) |
| | NCOR2 | NCOR2 isoform 6. (2461 aa) |
| | FBXL3 | F-box and leucine rich repeat protein 3. (428 aa) |
| | EGLN3 | EGLN3 isoform 1. (239 aa) |
| | CR201_G0009767 | HIF1A isoform 5. (735 aa) |
| | ESR2 | ESR2 isoform 12. (531 aa) |
| | RORA | RORA isoform 12. (555 aa) |
| | CA12 | CA12 isoform 1; Belongs to the alpha-carbonic anhydrase family. (354 aa) |
| | CRABP1 | Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa) |
| | ARNT2 | ARNT2 isoform 3. (610 aa) |
| | IQCK | IQCK isoform 1. (287 aa) |
| | PER1 | PER1 isoform 10. (1110 aa) |
| | NCOR1 | NCOR1 isoform 1. (2467 aa) |
| | RARA | RARA isoform 2. (460 aa) |
| | NR1D1 | NR1D1 isoform 1. (612 aa) |
| | CSNK1D | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] (404 aa) |
| | EGLN2 | T0155508 isoform 1. (407 aa) |
| | HIF3A | HIF3A isoform 1. (613 aa) |
| | NPAS1 | NPAS1 isoform 1. (590 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1420 aa) |
| | ENSPPYP00000012589 | Putative nuclear receptor corepressor 1-like protein NCOR1P1. (101 aa) |
| | NRIP1 | NRIP1 isoform 1. (1141 aa) |
| | LOC100447547 | T0085674 isoform 1; Belongs to the protein kinase superfamily. (416 aa) |
| | TEF | TEF transcription factor, PAR bZIP family member. (273 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (474 aa) |
| | NPAS2 | NPAS2 isoform 1. (889 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (869 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1293 aa) |
| | PER2 | PER2 isoform 2. (1226 aa) |
| | SLC49A4 | Solute carrier family 49 member 4. (478 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma. (477 aa) |
| | BHLHE40 | Class E basic helix-loop-helix protein 40; Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1/2 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK- ARNTL/BMAL1|ARNTL2/ [...] (412 aa) |
| | RARB | RARB isoform 2. (526 aa) |
| | THRB | THRB isoform 4. (460 aa) |
| | NR1D2 | NR1D2 isoform 1. (504 aa) |
| | TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (514 aa) |
| | CLOCK | Circadian locomoter output cycles protein kaput; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, [...] (846 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activi [...] (428 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | NCOA7 | NCOA7 isoform 1. (900 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | RXRB | Retinoid X receptor beta. (536 aa) |
| | FABP5 | FABP5 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | FABP9 | FABP9 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | FABP4 | Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | FABP12 | FABP12 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | CA9 | Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (465 aa) |
| | RORB | RORB isoform 1. (516 aa) |
| | NFIL3 | Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa) |
| | RXRA | RXRA isoform 2. (456 aa) |
| | TBL1X | TBL1X isoform 1. (587 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1464 aa) |
| | ENSPPYP00000024510 | annotation not available (85 aa) |
