(5 nodes) Endosomal lumen acidification network (Pongo abelii)

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Your Input:
	ATP6V0B	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family. (156 aa)
	ATP6V0C	V-type H+-transporting ATPase 16kDa proteolipid subunit. (128 aa)
	ATP6V0A1	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). (862 aa)
	ATP6V1H	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (465 aa)
	ATP6AP1	ATPase H+ transporting accessory protein 1. (475 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6AP1	ATP6V0A1	ENSPPYP00000023369	ENSPPYP00000009433	ATPase H+ transporting accessory protein 1.	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	0.994
ATP6AP1	ATP6V0B	ENSPPYP00000023369	ENSPPYP00000001666	ATPase H+ transporting accessory protein 1.	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	0.998
ATP6AP1	ATP6V0C	ENSPPYP00000023369	ENSPPYP00000007925	ATPase H+ transporting accessory protein 1.	V-type H+-transporting ATPase 16kDa proteolipid subunit.	0.998
ATP6AP1	ATP6V1H	ENSPPYP00000023369	ENSPPYP00000020844	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.997
ATP6V0A1	ATP6AP1	ENSPPYP00000009433	ENSPPYP00000023369	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	ATPase H+ transporting accessory protein 1.	0.994
ATP6V0A1	ATP6V0B	ENSPPYP00000009433	ENSPPYP00000001666	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	0.998
ATP6V0A1	ATP6V0C	ENSPPYP00000009433	ENSPPYP00000007925	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	V-type H+-transporting ATPase 16kDa proteolipid subunit.	0.998
ATP6V0A1	ATP6V1H	ENSPPYP00000009433	ENSPPYP00000020844	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.996
ATP6V0B	ATP6AP1	ENSPPYP00000001666	ENSPPYP00000023369	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	ATPase H+ transporting accessory protein 1.	0.998
ATP6V0B	ATP6V0A1	ENSPPYP00000001666	ENSPPYP00000009433	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	0.998
ATP6V0B	ATP6V0C	ENSPPYP00000001666	ENSPPYP00000007925	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	V-type H+-transporting ATPase 16kDa proteolipid subunit.	0.999
ATP6V0B	ATP6V1H	ENSPPYP00000001666	ENSPPYP00000020844	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.998
ATP6V0C	ATP6AP1	ENSPPYP00000007925	ENSPPYP00000023369	V-type H+-transporting ATPase 16kDa proteolipid subunit.	ATPase H+ transporting accessory protein 1.	0.998
ATP6V0C	ATP6V0A1	ENSPPYP00000007925	ENSPPYP00000009433	V-type H+-transporting ATPase 16kDa proteolipid subunit.	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	0.998
ATP6V0C	ATP6V0B	ENSPPYP00000007925	ENSPPYP00000001666	V-type H+-transporting ATPase 16kDa proteolipid subunit.	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	0.999
ATP6V0C	ATP6V1H	ENSPPYP00000007925	ENSPPYP00000020844	V-type H+-transporting ATPase 16kDa proteolipid subunit.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.997
ATP6V1H	ATP6AP1	ENSPPYP00000020844	ENSPPYP00000023369	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	ATPase H+ transporting accessory protein 1.	0.997
ATP6V1H	ATP6V0A1	ENSPPYP00000020844	ENSPPYP00000009433	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity).	0.996
ATP6V1H	ATP6V0B	ENSPPYP00000020844	ENSPPYP00000001666	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family.	0.998
ATP6V1H	ATP6V0C	ENSPPYP00000020844	ENSPPYP00000007925	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	V-type H+-transporting ATPase 16kDa proteolipid subunit.	0.997