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| | USH2A | USH2A isoform 2. (4749 aa) |
| | CRB1 | Crumbs cell polarity complex component 1. (1406 aa) |
| | EPS8L3 | EPS8L3 isoform 5. (593 aa) |
| | GPSM2 | GPSM2 isoform 1. (684 aa) |
| | PATJ | PATJ isoform 4. (1788 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (147 aa) |
| | GJB3 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (270 aa) |
| | CLIC4 | Chloride intracellular channel protein 4; Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. May play a role in angiogenesis (By similarity). (253 aa) |
| | ARHGEF10L | Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. (1034 aa) |
| | ESPN | ESPN isoform 1. (848 aa) |
| | CR201_G0025573 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (529 aa) |
| | MYO3A | MYO3A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1575 aa) |
| | PARD3 | PARD3 isoform 5. (1353 aa) |
| | CR201_G0030294 | CDH23 isoform 6. (250 aa) |
| | CDH23 | CDH23 isoform 1. (2498 aa) |
| | STOX1 | STOX1 isoform 1. (989 aa) |
| | PCDH15 | PCDH15 isoform 18. (1163 aa) |
| | PDZD7 | PDZ domain-containing protein 7; In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1. (477 aa) |
| | CDHR5 | CDHR5 isoform 1. (768 aa) |
| | CABP2 | Calcium binding protein 2. (220 aa) |
| | OTOG | OTOG isoform 2. (2803 aa) |
| | USH1C | USH1C isoform 9. (403 aa) |
| | INSC | INSC isoform 1. (579 aa) |
| | ENSPPYP00000004094 | annotation not available (264 aa) |
| | CR201_G0023224 | MYO7A isoform 2. (1350 aa) |
| | RDX | RDX isoform 3. (604 aa) |
| | TMPRSS4 | TMPRSS4 isoform 1; Belongs to the peptidase S1 family. (437 aa) |
| | PDZD3 | PDZ domain containing 3. (491 aa) |
| | TECTA | TECTA isoform 1. (2155 aa) |
| | ESAM | Endothelial cell adhesion molecule. (390 aa) |
| | CR201_G0026161 | USH1C isoform 8. (559 aa) |
| | EPS8 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] (824 aa) |
| | TWF1 | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. (384 aa) |
| | AVIL | AVIL isoform 2. (819 aa) |
| | OTOGL | Otogelin-like protein. (674 aa) |
| | VEZT | Vezatin; Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process. (779 aa) |
| | SRRM4 | SRRM4 isoform 1. (520 aa) |
| | GJB2 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa) |
| | LOC100442324 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (725 aa) |
| | LNX2 | Ligand of numb-protein X 2. (690 aa) |
| | CLDN10 | Claudin-10; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production an [...] (227 aa) |
| | CR201_G0055387 | PhoLip_ATPase_N domain-containing protein. (108 aa) |
| | MPP5 | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] (678 aa) |
| | NUMB | NUMB endocytic adaptor protein. (651 aa) |
| | TJP1 | TJP1 isoform 1; Belongs to the MAGUK family. (1746 aa) |
| | CR201_G0045973 | STRC isoform 2. (1473 aa) |
| | CR201_G0042177 | CIB2 isoform 1. (346 aa) |
| | TMC3 | Transmembrane channel-like protein. (1107 aa) |
| | CR201_G0014777 | CIB1 isoform 1. (190 aa) |
| | SLC9A3R2 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | ANKS4B | Ankyrin repeat and sterile alpha motif domain containing 4B. (417 aa) |
| | CR201_G0052461 | SDR42E2 isoform 1. (336 aa) |
| | OTOA | OTOA isoform 2. (700 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (346 aa) |
| | MARVELD3 | MARVELD3 isoform 2. (255 aa) |
| | NXN | NXN isoform 1. (390 aa) |
| | MYO1C | MYO1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa) |
| | CLDN7 | Claudin-7. (211 aa) |
| | MYO15A | MYO15A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3281 aa) |
| | CPD | CPD isoform 1. (1243 aa) |
| | PLEKHH3 | PLEKHH3 isoform 3. (756 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (357 aa) |
| | USH1G | USH1G isoform 1. (517 aa) |
| | LLGL2 | LLGL scribble cell polarity complex component 2; Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par- 6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity (By similarity); Belongs to the WD repeat L(2)GL family. (1017 aa) |
| | TJP3 | TJP3 isoform 5; Belongs to the MAGUK family. (807 aa) |
| | CRB3 | CRB3 isoform 3. (123 aa) |
| | ENSPPYP00000010854 | annotation not available (137 aa) |
| | LSR | Lipolysis stimulated lipoprotein receptor. (602 aa) |
| | NUMBL | NUMBL isoform 1. (418 aa) |
| | CEACAM16 | CEACAM16 isoform 1. (482 aa) |
| | EPS8L1 | EPS8L1 isoform 4. (714 aa) |
| | TMC2 | Transmembrane channel-like protein. (905 aa) |
| | SLC52A3 | Solute carrier family 52 member 3. (469 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (849 aa) |
| | ENSPPYP00000012234 | Fer-1-like protein 4. (1751 aa) |
| | PARD6B | Par-6 family cell polarity regulator beta. (372 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | CLIC6 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (677 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa) |
| | TMPRSS3 | TMPRSS3 isoform 1; Belongs to the peptidase S1 family. (481 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | TRIOBP | TRIOBP isoform 1. (2199 aa) |
| | CAPG | Capping actin protein, gelsolin like. (348 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (733 aa) |
| | MYO3B | MYO3B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1306 aa) |
| | PJVK | DFNB59 isoform 1. (352 aa) |
| | MYO1B | MYO1B isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (974 aa) |
| | PARD3B | Partitioning defective 3 homolog B isoform X1. (1026 aa) |
| | ESPNL | ESPNL isoform 1. (1002 aa) |
| | ILDR1 | Immunoglobulin-like domain-containing receptor 1; Putative membrane receptor. (546 aa) |
| | CR201_G0034913 | TMIE isoform 1. (193 aa) |
| | VILL | VILL isoform 1. (855 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | PLS1 | PLS1 isoform 1. (631 aa) |
| | CLRN1 | CLRN1 isoform 2. (232 aa) |
| | AADACL2 | AADACL2 isoform 2. (401 aa) |
| | PRKCI | Protein kinase C iota type; Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process [...] (690 aa) |
| | CLDN11 | Claudin-11; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. (207 aa) |
| | TTC14 | TTC14 isoform 1. (769 aa) |
| | DNAJC19 | Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). (116 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (305 aa) |
| | ENSPPYP00000016185 | annotation not available (59 aa) |
| | GRXCR1 | GRXCR1 isoform 1. (231 aa) |
| | SLAIN2 | SLAIN2 isoform 1. (586 aa) |
| | LNX1 | LNX1 isoform 2. (556 aa) |
| | CLDN22 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | CLDN24 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (205 aa) |
| | ANKRD33B | ANKRD33B isoform 2. (293 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. (522 aa) |
| | ADGRV1 | ADGRV1 isoform 3; Belongs to the G-protein coupled receptor 2 family. (6076 aa) |
| | GRXCR2 | Glutaredoxin and cysteine rich domain containing 2. (248 aa) |
| | CDHR2 | CDHR2 isoform 1. (778 aa) |
| | RIPOR2 | T0162759 isoform 1. (1097 aa) |
| | PPP1R18 | PPP1R18 isoform 1. (614 aa) |
| | CLIC5 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (205 aa) |
| | COL10A1 | Collagen type X alpha 1 chain. (680 aa) |
| | GOPC | Golgi-associated PDZ and coiled-coil motif-containing protein; Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes (By similarity). (445 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | EZR | EZR isoform 1. (586 aa) |
| | FSCN1 | FSCN1 isoform 3. (444 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | CLDN12 | Claudin-12; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. (244 aa) |
| | SLC26A5 | Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (722 aa) |
| | LHFPL3 | LHFPL3 isoform 1. (234 aa) |
| | SLC26A4 | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (778 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa) |
| | PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (513 aa) |
| | SLC45A4 | SLC45A4 isoform 2. (652 aa) |
| | TMC1 | Transmembrane channel-like protein. (761 aa) |
| | WHRN | WHRN isoform 2. (907 aa) |
| | CRB2 | CRB2 isoform 2. (637 aa) |
| | TPRN | TPRN isoform 2. (404 aa) |
| | MSN | MSN isoform 6. (577 aa) |
| | POU3F4 | POU domain protein. (361 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | MPP1 | 55 kDa erythrocyte membrane protein; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). Belongs to the MAGUK family. (466 aa) |
| | CLIC2 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa) |
| | ENSPPYP00000023721 | annotation not available (169 aa) |
| | PLS3 | PLS3 isoform 2. (639 aa) |
