STRINGSTRING
SPTA1 SPTA1 CR201_G0015864 CR201_G0015864 ANK3 ANK3 ADD3 ADD3 SPTBN2 SPTBN2 CR201_G0009827 CR201_G0009827 SPTBN5 SPTBN5 CR201_G0043999 CR201_G0043999 ANKRD60 ANKRD60 ADD2 ADD2 SPTBN1 SPTBN1 CR201_G0017951 CR201_G0017951 ADD1 ADD1 ANK2 ANK2 NRCAM NRCAM DMTN DMTN ANK1 ANK1 SPTAN1 SPTAN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPTA1SPTA1 isoform 1. (2387 aa)
CR201_G0015864EPB41 isoform 1. (655 aa)
ANK3ANK3 isoform 1. (4275 aa)
ADD3ADD3 isoform 3. (706 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2389 aa)
CR201_G0009827Spectrin beta chain; Belongs to the spectrin family. (1818 aa)
SPTBN5SPTBN5 isoform 1. (3674 aa)
CR201_G0043999SPTBN4 isoform 1. (2409 aa)
ANKRD60ANKRD60 isoform 1. (140 aa)
ADD2Beta-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit (By similarity). Belongs to the aldolase class II family. Adducin subfamily. (726 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2342 aa)
CR201_G0017951GYPC isoform 2. (119 aa)
ADD1Alpha-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin (By similarity); Belongs to the aldolase class II family. Adducin subfamily. (631 aa)
ANK2ANK2 isoform 1. (4018 aa)
NRCAMNRCAM isoform 11. (1253 aa)
DMTNDematin; Membrane-cytoskeleton-associated protein with F-actin-binding activity that induces F-actin bundles formation and stabilization. Its F-actin-bundling activity is reversibly regulated upon its phosphorylation by the cAMP-dependent protein kinase A (PKA). Binds to the erythrocyte membrane glucose transporter-1 SLC2A1/GLUT1, and hence stabilizes and attaches the spectrin-actin network to the erythrocytic plasma membrane. Plays a role in maintaining the functional integrity of PKA-activated erythrocyte shape and the membrane mechanical properties. Plays also a role as a modulator [...] (405 aa)
ANK1Ankyrin-1 isoform X1. (1695 aa)
SPTAN1SPTAN1 isoform 10. (2538 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.