STRINGSTRING
AGT AGT AVPR1B AVPR1B KISS1 KISS1 REN REN ADORA1 ADORA1 ENSPPYP00000001083 ENSPPYP00000001083 TMIGD3 TMIGD3 PROK1 PROK1 LEPR LEPR EDN2 EDN2 HCRTR1 HCRTR1 OPRD1 OPRD1 UTS2 UTS2 CR201_G0054735 CR201_G0054735 NPFFR1 NPFFR1 TACR2 TACR2 PRLHR PRLHR NPS NPS GAL GAL PLCB3 PLCB3 CCKBR CCKBR SPX SPX NPFF NPFF TAC3 TAC3 ARHGEF25 ARHGEF25 AVPR1A AVPR1A NTS NTS PMCH PMCH MLNR MLNR SSTR1 SSTR1 GNG2 GNG2 BDKRB2 BDKRB2 BDKRB1 BDKRB1 NMB NMB SSTR5 SSTR5 NPW NPW AGRP AGRP PPY PPY HCRT HCRT GAST GAST ACE ACE SSTR2 SSTR2 GALR2 GALR2 NPB NPB UTS2R UTS2R TAC4 TAC4 MC2R MC2R GRP GRP MC4R MC4R GALR1 GALR1 KISS1R KISS1R GNA11 GNA11 CR201_G0044254 CR201_G0044254 GALP GALP PLCB1 PLCB1 SSTR4 SSTR4 PROKR2 PROKR2 ADRA1D ADRA1D AVP AVP OXT OXT GNRH2 GNRH2 PDYN PDYN MC3R MC3R EDN3 EDN3 NTSR1 NTSR1 OPRL1 OPRL1 NPBWR2 NPBWR2 MRAP MRAP LGALS2 LGALS2 GALR3 GALR3 CR201_G0031976 CR201_G0031976 NMS NMS CR201_G0053532 CR201_G0053532 TACR1 TACR1 PROKR1 PROKR1 POMC POMC NTSR2 NTSR2 GPR39 GPR39 RPRM RPRM NMUR1 NMUR1 PRLH PRLH CASR CASR HRH1 HRH1 GHRL GHRL OXTR OXTR PROK2 PROK2 CCK CCK PXYLP1 PXYLP1 AGTR1 AGTR1 GHSR GHSR KNG1 KNG1 SST SST UTS2B UTS2B CCKAR CCKAR GNRHR GNRHR NMU NMU NPFFR2 NPFFR2 TACR3 TACR3 QRFPR QRFPR EDNRA EDNRA NPY1R NPY1R NPY5R NPY5R NPY2R NPY2R ENSPPYP00000017161 ENSPPYP00000017161 NLN NLN ENSPPYP00000017683 ENSPPYP00000017683 ADRA1B ADRA1B EDN1 EDN1 MAS1L MAS1L MLN MLN HCRTR2 HCRTR2 MRAP2 MRAP2 MCHR2 MCHR2 GPRC6A GPRC6A NMBR NMBR NPSR1 NPSR1 NPVF NPVF NPY NPY TAC1 TAC1 SDHAF3 SDHAF3 LEP LEP ENSPPYP00000020449 ENSPPYP00000020449 GNRH1 GNRH1 ADRA1A ADRA1A PNOC PNOC MBOAT4 MBOAT4 NPBWR1 NPBWR1 OPRK1 OPRK1 PENK PENK CHD7 CHD7 OXR1 OXR1 GNA14 GNA14 GNAQ GNAQ NSMF NSMF QRFP QRFP ANOS1 ANOS1 GRPR GRPR ATP6AP2 ATP6AP2 CR201_G0023677 CR201_G0023677 CR201_G0025183 CR201_G0025183 AGTR2 AGTR2 BRS3 BRS3 OPRM1 OPRM1 EDNRB EDNRB PLCB4 PLCB4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGTAGT isoform 1; Belongs to the serpin family. (485 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (425 aa)
KISS1KISS1 isoform 2. (147 aa)
RENREN isoform 1; Belongs to the peptidase A1 family. (406 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family. (326 aa)
ENSPPYP00000001083Gonadotropin-releasing hormone II receptor. (286 aa)
TMIGD3TMIGD3 isoform 3; Belongs to the G-protein coupled receptor 1 family. (346 aa)
PROK1PROK1 isoform 1. (105 aa)
LEPRLeptin receptor. (1165 aa)
EDN2EDN2 isoform 2. (178 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
UTS2UTS2 isoform 3. (139 aa)
CR201_G0054735NPY4R isoform 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
NPFFR1NPFFR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (430 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
PRLHRProlactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
NPSNeuropeptide S. (89 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa)
CCKBRCCKBR isoform 1; Belongs to the G-protein coupled receptor 1 family. (447 aa)
SPXSpexin hormone. (116 aa)
NPFFPro-FMRFamide-related neuropeptide FF isoform X2. (113 aa)
TAC3TAC3 isoform 1. (121 aa)
ARHGEF25ARHGEF25 isoform 6. (473 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
NTSNTS isoform 1. (170 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
MLNRMLNR isoform 1; Belongs to the G-protein coupled receptor 1 family. (411 aa)
SSTR1SSTR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (389 aa)
GNG2Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). (71 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
BDKRB1B1 bradykinin receptor isoform X2. (353 aa)
NMBNMB isoform 2. (154 aa)
SSTR5SSTR5 isoform 1; Belongs to the G-protein coupled receptor 1 family. (378 aa)
NPWNeuropeptide W. (165 aa)
AGRPAgouti related neuropeptide. (132 aa)
PPYPancreatic polypeptide. (95 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
GASTGAST isoform 1. (102 aa)
ACEAngiotensin-converting enzyme. (1270 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
NPBNPB isoform 2. (125 aa)
UTS2RUTS2R isoform 1; Belongs to the G-protein coupled receptor 1 family. (132 aa)
TAC4TAC4 isoform 7. (96 aa)
MC2RMelanocortin 2 receptor. (297 aa)
GRPGastrin releasing peptide. (142 aa)
MC4RMelanocortin 4 receptor. (332 aa)
GALR1GALR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
KISS1RKISS1R isoform 1. (342 aa)
GNA11GNA11 isoform 1. (358 aa)
CR201_G0044254GNA15 isoform 1. (287 aa)
GALPGalanin like peptide. (116 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)
SSTR4SSTR4 isoform 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
PROKR2Prokineticin receptor 2. (349 aa)
ADRA1DAdrenoceptor alpha 1D. (573 aa)
AVPAVP isoform 1; Belongs to the vasopressin/oxytocin family. (164 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
GNRH2LOW QUALITY PROTEIN: progonadoliberin-2. (96 aa)
PDYNPDYN isoform 1. (254 aa)
MC3RMelanocortin 3 receptor. (323 aa)
EDN3EDN3 isoform 1. (229 aa)
NTSR1NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
OPRL1Opioid related nociceptin receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
NPBWR2Neuropeptides B and W receptor 2; Belongs to the G-protein coupled receptor 1 family. (333 aa)
MRAPMRAP isoform 4. (101 aa)
LGALS2Galectin. (130 aa)
GALR3GALR3 isoform 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CR201_G0031976MCHR1 isoform 3. (297 aa)
NMSNMS isoform 1. (153 aa)
CR201_G0053532IGKV2-30 isoform 1. (93 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
PROKR1APLF isoform 2; Belongs to the G-protein coupled receptor 1 family. (393 aa)
POMCPOMC isoform 1. (266 aa)
NTSR2NTSR2 isoform 1; Belongs to the G-protein coupled receptor 1 family. (410 aa)
GPR39GPR39 isoform 1; Belongs to the G-protein coupled receptor 1 family. (458 aa)
RPRMReprimo, TP53 dependent G2 arrest mediator homolog. (109 aa)
NMUR1NMUR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (420 aa)
PRLHProlactin releasing hormone. (87 aa)
CASRCalcium sensing receptor. (1078 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
PROK2PROK2 isoform 2. (129 aa)
CCKCholecystokinin. (115 aa)
PXYLP12-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family. (480 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
KNG1KNG1 isoform 1. (427 aa)
SSTSST isoform 1. (116 aa)
UTS2BUTS2B isoform 1. (119 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
GNRHRGNRHR isoform 1; Belongs to the G-protein coupled receptor 1 family. (183 aa)
NMUNMU isoform 2. (174 aa)
NPFFR2NPFFR2 isoform 3; Belongs to the G-protein coupled receptor 1 family. (521 aa)
TACR3TACR3 isoform 1; Belongs to the G-protein coupled receptor 1 family. (465 aa)
QRFPRPyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa)
EDNRAEDNRA isoform 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
NPY5RNeuropeptide Y receptor Y5. (445 aa)
NPY2RNeuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (381 aa)
ENSPPYP00000017161annotation not available (85 aa)
NLNNeurolysin, mitochondrial; Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A; Belongs to the peptidase M3 family. (650 aa)
ENSPPYP00000017683annotation not available (137 aa)
ADRA1BADRA1B isoform 3. (517 aa)
EDN1EDN1 isoform 1. (212 aa)
MAS1LMas-related G-protein coupled receptor MRG. (375 aa)
MLNMLN isoform 1. (138 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
MRAP2MRAP2 isoform 1. (181 aa)
MCHR2Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family. (340 aa)
GPRC6AGPRC6A isoform 3. (928 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
NPSR1Neuropeptide S receptor 1. (371 aa)
NPVFNeuropeptide VF precursor. (196 aa)
NPYNPY isoform 1. (97 aa)
TAC1TAC1 isoform 1. (129 aa)
SDHAF3Succinate dehydrogenase complex assembly factor 3. (125 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ENSPPYP00000020449annotation not available (62 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
ADRA1AAdrenoceptor alpha 1A. (427 aa)
PNOCPrepronociceptin. (176 aa)
MBOAT4MBOAT4 isoform 1; Belongs to the membrane-bound acyltransferase family. (327 aa)
NPBWR1Neuropeptides B and W receptor 1; Belongs to the G-protein coupled receptor 1 family. (328 aa)
OPRK1Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PENKPENK isoform 3. (267 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
OXR1Oxidation resistance 1. (874 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAQG protein subunit alpha q. (359 aa)
NSMFNSMF isoform 4. (474 aa)
QRFPQRFP isoform 1. (136 aa)
ANOS1ANOS1 isoform 1. (680 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
ATP6AP2Renin receptor extracellular fragment; Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton- transporting vacuolar (V)-ATPase protein pump. May mediate renin- dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity). Probably by controlling the assembly of the V- ATPase pump and thus the acidification of the endo-lysosomal system, plays a [...] (350 aa)
CR201_G0023677PYY isoform 1. (70 aa)
CR201_G0025183CYSLTR1 isoform 1. (197 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
BRS3Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (399 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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