STRINGSTRING
UBXN10 UBXN10 UBXN1 UBXN1 ASPSCR1 ASPSCR1 UBXN6 UBXN6 NSFL1C NSFL1C UFD1 UFD1 UBXN2A UBXN2A UBXN7 UBXN7 FAF2 FAF2 UBXN2B UBXN2B VCPIP1 VCPIP1 VCP VCP NPLOC4 NPLOC4 FAF1 FAF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBXN10UBXN10 isoform 1. (280 aa)
UBXN1UBXN1 isoform 1. (296 aa)
ASPSCR1ASPSCR1 isoform 2. (553 aa)
UBXN6UBXN6 isoform 3. (436 aa)
NSFL1CNSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. (370 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
UBXN2AUBXN2A isoform 2. (261 aa)
UBXN7UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). (489 aa)
FAF2Fas associated factor family member 2. (445 aa)
UBXN2BUBX domain protein 2B. (331 aa)
VCPIP1VCPIP1 isoform 1. (1224 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1. (806 aa)
NPLOC4NPLOC4 isoform 1. (609 aa)
FAF1Fas associated factor 1. (650 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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