(5 nodes) Histone deacetylase, glutamine rich N-terminal domain, and Histone H2B network (Pongo abelii)

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Your Input:
	HDAC5	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...] (1111 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1050 aa)
	LOC100445948	Histone H2B type 1-like. (128 aa)
	LOC100431754	Histone H2A; Belongs to the histone H2A family. (130 aa)
	CR201_G0020495	H2BFM isoform 1; Belongs to the histone H2B family. (253 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0020495	HDAC4	ENSPPYP00000023425	ENSPPYP00000014905	H2BFM isoform 1; Belongs to the histone H2B family.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.735
CR201_G0020495	HDAC5	ENSPPYP00000023425	ENSPPYP00000009379	H2BFM isoform 1; Belongs to the histone H2B family.	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	0.735
CR201_G0020495	LOC100431754	ENSPPYP00000023425	ENSPPYP00000018268	H2BFM isoform 1; Belongs to the histone H2B family.	Histone H2A; Belongs to the histone H2A family.	0.562
HDAC4	CR201_G0020495	ENSPPYP00000014905	ENSPPYP00000023425	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	H2BFM isoform 1; Belongs to the histone H2B family.	0.735
HDAC4	HDAC5	ENSPPYP00000014905	ENSPPYP00000009379	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	0.923
HDAC4	LOC100431754	ENSPPYP00000014905	ENSPPYP00000018268	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone H2A; Belongs to the histone H2A family.	0.718
HDAC4	LOC100445948	ENSPPYP00000014905	ENSPPYP00000018254	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone H2B type 1-like.	0.735
HDAC5	CR201_G0020495	ENSPPYP00000009379	ENSPPYP00000023425	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	H2BFM isoform 1; Belongs to the histone H2B family.	0.735
HDAC5	HDAC4	ENSPPYP00000009379	ENSPPYP00000014905	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.923
HDAC5	LOC100431754	ENSPPYP00000009379	ENSPPYP00000018268	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	Histone H2A; Belongs to the histone H2A family.	0.718
HDAC5	LOC100445948	ENSPPYP00000009379	ENSPPYP00000018254	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	Histone H2B type 1-like.	0.735
LOC100431754	CR201_G0020495	ENSPPYP00000018268	ENSPPYP00000023425	Histone H2A; Belongs to the histone H2A family.	H2BFM isoform 1; Belongs to the histone H2B family.	0.562
LOC100431754	HDAC4	ENSPPYP00000018268	ENSPPYP00000014905	Histone H2A; Belongs to the histone H2A family.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.718
LOC100431754	HDAC5	ENSPPYP00000018268	ENSPPYP00000009379	Histone H2A; Belongs to the histone H2A family.	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	0.718
LOC100431754	LOC100445948	ENSPPYP00000018268	ENSPPYP00000018254	Histone H2A; Belongs to the histone H2A family.	Histone H2B type 1-like.	0.588
LOC100445948	HDAC4	ENSPPYP00000018254	ENSPPYP00000014905	Histone H2B type 1-like.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.735
LOC100445948	HDAC5	ENSPPYP00000018254	ENSPPYP00000009379	Histone H2B type 1-like.	Histone deacetylase 5; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By s [...]	0.735
LOC100445948	LOC100431754	ENSPPYP00000018254	ENSPPYP00000018268	Histone H2B type 1-like.	Histone H2A; Belongs to the histone H2A family.	0.588