STRINGSTRING
SHROOM3 SHROOM3 DLG1 DLG1 TNK2 TNK2 ENSPPYP00000016075 ENSPPYP00000016075 ENSPPYP00000016072 ENSPPYP00000016072 KLHL24 KLHL24 CTNNB1 CTNNB1 LIMD1 LIMD1 MAGI1 MAGI1 FRMD4B FRMD4B TMEM204 TMEM204 PARK7 PARK7 PVR PVR CEACAM1 CEACAM1 CAMSAP3 CAMSAP3 OXTR OXTR NECTIN3 NECTIN3 EPHA4 EPHA4 PARD3B PARD3B ABI2 ABI2 BMPR2 BMPR2 MPP4 MPP4 PKP4 PKP4 EPB41L5 EPB41L5 ENSPPYP00000014193 ENSPPYP00000014193 CCDC85A CCDC85A CTNNA2 CTNNA2 NPHP1 NPHP1 CDC42EP1 CDC42EP1 MYH9 MYH9 NF2 NF2 ARVCF ARVCF CXADR CXADR CDH22 CDH22 JAG1 JAG1 LIN7B LIN7B CYTH2 CYTH2 AJAP1 AJAP1 CR201_G0018317 CR201_G0018317 MPP7 MPP7 JCAD JCAD PARD3 PARD3 DLG5 DLG5 VCL VCL CTNNA3 CTNNA3 PDLIM1 PDLIM1 SORBS1 SORBS1 CR201_G0053124 CR201_G0053124 PPP1CA PPP1CA CCDC85B CCDC85B CTNND1 CTNND1 TNKS1BP1 TNKS1BP1 LIN7C LIN7C PLEKHA7 PLEKHA7 KLHL35 KLHL35 DLG2 DLG2 RDX RDX NECTIN1 NECTIN1 ESAM ESAM ENSPPYP00000004606 ENSPPYP00000004606 CDCA3 CDCA3 PKP2 PKP2 RND1 RND1 KRT18 KRT18 FRS2 FRS2 LIN7A LIN7A VEZT VEZT TRPV4 TRPV4 LMO7 LMO7 EFNB2 EFNB2 AJUBA AJUBA CDH24 CDH24 STXBP6 STXBP6 FERMT2 FERMT2 MPP5 MPP5 CCDC85C CCDC85C PAK4 PAK4 WTIP WTIP CR201_G0044279 CR201_G0044279 CDH19 CDH19 CDH7 CDH7 CDH20 CDH20 DSC2 DSC2 PPP1R9B PPP1R9B TBCD TBCD BAIAP2 BAIAP2 CYTH1 CYTH1 CDC42EP4 CDC42EP4 SYNM SYNM MYO1E MYO1E ADAM10 ADAM10 TMOD3 TMOD3 SNAP23 SNAP23 CR201_G0050697 CR201_G0050697 JUP JUP FLOT2 FLOT2 LLGL1 LLGL1 ALOX15B ALOX15B DLG4 DLG4 CDH3 CDH3 CDH5 CDH5 CDH11 CDH11 CDH8 CDH8 KIFC3 KIFC3 FLOT1 FLOT1 LDB3 LDB3 LAMA3 LAMA3 APC APC FRMD5 FRMD5 SHROOM4 SHROOM4 KLHL6 KLHL6 PDZD11 PDZD11 CD99L2 CD99L2 ENSPPYP00000022983 ENSPPYP00000022983 POF1B POF1B DLG3 DLG3 MSN MSN WNK3 WNK3 TMEM47 TMEM47 SHROOM2 SHROOM2 NOTCH1 NOTCH1 NIBAN2 NIBAN2 CR201_G0001575 CR201_G0001575 TLN1 TLN1 SCRIB SCRIB NDRG1 NDRG1 SDCBP SDCBP LYN LYN PDLIM2 PDLIM2 CDHR3 CDHR3 ZYX ZYX BAIAP2L1 BAIAP2L1 CYTH3 CYTH3 ACTB ACTB DLL1 DLL1 AFDN AFDN EZR EZR AHI1 AHI1 PTPRK PTPRK ENSPPYP00000018739 ENSPPYP00000018739 TOMM6 TOMM6 PDLIM7 PDLIM7 FAT2 FAT2 CTNNA1 CTNNA1 SHROOM1 SHROOM1 PDLIM4 PDLIM4 EFNA5 EFNA5 CDH6 CDH6 TJP1 TJP1 CDH9 CDH9 CDH10 CDH10 CR201_G0025391 CR201_G0025391 CDH18 CDH18 CTNND2 CTNND2 CR201_G0037913 CR201_G0037913 PDLIM5 PDLIM5 ARHGAP24 ARHGAP24 PKP1 PKP1 CRB1 CRB1 HMCN1 HMCN1 NECTIN4 NECTIN4 ADAM15 ADAM15 S100A11 S100A11 SSX2IP SSX2IP NEXN NEXN PLPP3 PLPP3 CR201_G0002520 CR201_G0002520 IGSF21 IGSF21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHROOM3SHROOM3 isoform 1. (1995 aa)
DLG1DLG1 isoform 5; Belongs to the MAGUK family. (922 aa)
TNK2TNK2 isoform 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
ENSPPYP00000016075annotation not available (42 aa)
ENSPPYP00000016072annotation not available (32 aa)
KLHL24Kelch like family member 24. (600 aa)
CTNNB1CTNNB1 isoform 2. (781 aa)
LIMD1LIM domains containing 1. (676 aa)
MAGI1MAGI1 isoform 5. (1293 aa)
FRMD4BFRMD4B isoform 1. (932 aa)
TMEM204Transmembrane protein 204. (226 aa)
PARK7PARK7 isoform 1. (189 aa)
PVRPVR isoform 2. (274 aa)
CEACAM1CEACAM1 isoform 2. (527 aa)
CAMSAP3CAMSAP3 isoform 2. (844 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
NECTIN3NECTIN3 isoform 3. (512 aa)
EPHA4EPHA4 isoform 2. (927 aa)
PARD3BPartitioning defective 3 homolog B isoform X1. (1026 aa)
ABI2ABI2 isoform 1. (551 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
MPP4MPP4 isoform 2; Belongs to the MAGUK family. (591 aa)
PKP4PKP4 isoform 2. (1192 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
ENSPPYP00000014193annotation not available (396 aa)
CCDC85ACCDC85A isoform 1. (523 aa)
CTNNA2Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of star [...] (905 aa)
NPHP1NPHP1 isoform 4. (733 aa)
CDC42EP1CDC42EP1 isoform 1. (391 aa)
MYH9MYH9 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1959 aa)
NF2Neurofibromin 2. (590 aa)
ARVCFARVCF isoform 1. (877 aa)
CXADRCoxsackievirus and adenovirus receptor homolog; Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induc [...] (365 aa)
CDH22CDH22 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (690 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
CYTH2T0102787 isoform 1. (399 aa)
AJAP1AJAP1 isoform 1. (404 aa)
CR201_G0018317FRMD4A isoform 1. (832 aa)
MPP7MPP7 isoform 1; Belongs to the MAGUK family. (504 aa)
JCADJCAD isoform 1. (1358 aa)
PARD3PARD3 isoform 5. (1353 aa)
DLG5DLG5 isoform 1; Belongs to the MAGUK family. (1809 aa)
VCLVCL isoform 2. (1134 aa)
CTNNA3CTNNA3 isoform 1. (895 aa)
PDLIM1PDZ and LIM domain 1. (329 aa)
SORBS1SORBS1 isoform 10. (1292 aa)
CR201_G0053124PKP3 isoform 5. (638 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
CCDC85BCoiled-coil domain containing 85B. (202 aa)
CTNND1CTNND1 isoform 19. (968 aa)
TNKS1BP1TNKS1BP1 isoform 2. (1729 aa)
LIN7CProtein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may funct [...] (197 aa)
PLEKHA7PLEKHA7 isoform 2. (1297 aa)
KLHL35KLHL35 isoform 1. (437 aa)
DLG2DLG2 isoform 1. (735 aa)
RDXRDX isoform 3. (604 aa)
NECTIN1NECTIN1 isoform 1. (596 aa)
ESAMEndothelial cell adhesion molecule. (390 aa)
ENSPPYP00000004606annotation not available (133 aa)
CDCA3CDCA3 isoform 4. (268 aa)
PKP2PKP2 isoform 2. (829 aa)
RND1Rho family GTPase 1. (232 aa)
KRT18KRT18 isoform 1; Belongs to the intermediate filament family. (430 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
VEZTVezatin; Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process. (779 aa)
TRPV4TRPV4 isoform 2; Belongs to the transient receptor (TC 1.A.4) family. (699 aa)
LMO7LMO7 isoform 6. (1670 aa)
EFNB2EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
AJUBALIM domain-containing protein ajuba isoform X1. (538 aa)
CDH24CDH24 isoform 3; Cadherins are calcium-dependent cell adhesion proteins. (819 aa)
STXBP6STXBP6 isoform 1. (179 aa)
FERMT2FERMT2 isoform 1. (623 aa)
MPP5MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] (678 aa)
CCDC85CCCDC85C isoform 1. (419 aa)
PAK4Non-specific serine/threonine protein kinase. (645 aa)
WTIPWTIP isoform 1. (235 aa)
CR201_G0044279PIP5K1C isoform 1. (576 aa)
CDH19CDH19 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
CDH7CDH7 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (724 aa)
CDH20CDH20 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (712 aa)
DSC2DSC2 isoform 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (904 aa)
PPP1R9BPPP1R9B isoform 1. (729 aa)
TBCDTBCD isoform 3. (1192 aa)
BAIAP2BAI1 associated protein 2. (521 aa)
CYTH1CYTH1 isoform 4. (399 aa)
CDC42EP4CDC42 effector protein 4. (356 aa)
SYNMSYNM isoform 4; Belongs to the intermediate filament family. (1253 aa)
MYO1EMYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1109 aa)
ADAM10ADAM10 isoform 1. (748 aa)
TMOD3TMOD3 isoform 2. (352 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
CR201_G0050697FMN1 isoform 2. (812 aa)
JUPJUP isoform 1. (670 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
LLGL1LLGL1 isoform 2. (1051 aa)
ALOX15BALOX15B isoform 2. (676 aa)
DLG4DLG4 isoform 3; Belongs to the MAGUK family. (690 aa)
CDH3CDH3 isoform 2; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
CDH5CDH5 isoform 2; Cadherins are calcium-dependent cell adhesion proteins. (781 aa)
CDH11CDH11 isoform 6; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
CDH8CDH8 isoform 3; Cadherins are calcium-dependent cell adhesion proteins. (695 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (833 aa)
FLOT1Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa)
LDB3LDB3 isoform 8. (677 aa)
LAMA3LAMA3 isoform 1. (1233 aa)
APCAdenomatous polyposis coli protein isoform X2. (2861 aa)
FRMD5FRMD5 isoform 8. (419 aa)
SHROOM4SHROOM4 isoform 1. (1498 aa)
KLHL6KLHL6 isoform 1. (457 aa)
PDZD11PDZ domain containing 11. (140 aa)
CD99L2CD99 antigen-like protein 2. (261 aa)
ENSPPYP00000022983annotation not available (412 aa)
POF1BProtein POF1B; Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development (By similarity). (588 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa)
MSNMSN isoform 6. (577 aa)
WNK3WNK3 isoform 2. (1777 aa)
TMEM47Transmembrane protein 47. (181 aa)
SHROOM2SHROOM2 isoform 1. (1569 aa)
NOTCH1NOTCH1 isoform 1. (2107 aa)
NIBAN2FAM129B isoform 2. (702 aa)
CR201_G0001575PGM5 isoform 7; Belongs to the phosphohexose mutase family. (421 aa)
TLN1TLN1 isoform 1. (2541 aa)
SCRIBSCRIB isoform 2. (1472 aa)
NDRG1NDRG1 isoform 2. (408 aa)
SDCBPSDCBP isoform 3. (297 aa)
LYNTyrosine-protein kinase. (512 aa)
PDLIM2PDZ and LIM domain protein 1/2/3/4. (366 aa)
CDHR3CDHR3 isoform 2. (885 aa)
ZYXZYX isoform 1. (559 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (511 aa)
CYTH3CYTH3 isoform 1. (399 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
AFDNAFDN isoform 9. (1802 aa)
EZREZR isoform 1. (586 aa)
AHI1AHI1 isoform 11. (1046 aa)
PTPRKPTPRK isoform 7. (1485 aa)
ENSPPYP00000018739annotation not available (186 aa)
TOMM6Mitochondrial import receptor subunit TOM6 homolog isoform X2. (384 aa)
PDLIM7PDZ and LIM domain 7. (423 aa)
FAT2FAT2 isoform 2. (4141 aa)
CTNNA1CTNNA1 isoform 1. (905 aa)
SHROOM1Shroom family member 1. (852 aa)
PDLIM4PDZ and LIM domain 4. (330 aa)
EFNA5EFNA5 isoform 1; Belongs to the ephrin family. (228 aa)
CDH6CDH6 isoform 2; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
TJP1TJP1 isoform 1; Belongs to the MAGUK family. (1746 aa)
CDH9CDH9 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (702 aa)
CDH10CDH10 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
CR201_G0025391CDH12 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (793 aa)
CDH18CDH18 isoform 2; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
CTNND2CTNND2 isoform 1. (1204 aa)
CR201_G0037913PDLIM3 isoform 4. (286 aa)
PDLIM5PDLIM5 isoform 3. (596 aa)
ARHGAP24Rho GTPase activating protein 24. (748 aa)
PKP1PKP1 isoform 2. (745 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
HMCN1HMCN1 isoform 1. (5636 aa)
NECTIN4Nectin cell adhesion molecule 4. (509 aa)
ADAM15ADAM15 isoform 14. (750 aa)
S100A11Protein S100; Belongs to the S-100 family. (105 aa)
SSX2IPSSX family member 2 interacting protein. (614 aa)
NEXNNEXN isoform 3. (763 aa)
PLPP3T0071805 isoform 3. (313 aa)
CR201_G0002520PPP4R1 isoform 23. (42 aa)
IGSF21IGSF21 isoform 1. (414 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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