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| | RHOBTB1 | RHOBTB1 isoform 1. (696 aa) |
| | CR201_G0035777 | FMN2 isoform 2. (1572 aa) |
| | ACTN2 | ACTN2 isoform 1. (887 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) |
| | CAPN2 | CAPN2 isoform 2; Belongs to the peptidase C2 family. (655 aa) |
| | HMCN1 | HMCN1 isoform 1. (5636 aa) |
| | LAMC2 | LAMC2 isoform 2. (1059 aa) |
| | KIAA1614 | KIAA1614 isoform 2. (1219 aa) |
| | SELE | SELE isoform 3. (601 aa) |
| | SPTA1 | SPTA1 isoform 1. (2387 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa) |
| | SPRR4 | SPRR4 isoform 1. (76 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] (354 aa) |
| | GPSM2 | GPSM2 isoform 1. (684 aa) |
| | FNBP1L | Formin binding protein 1 like. (605 aa) |
| | KNCN | KNCN isoform 1. (123 aa) |
| | SLC2A1 | SLC2A1 isoform 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa) |
| | RIMS3 | RIMS3 isoform 1. (285 aa) |
| | CAP1 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. (475 aa) |
| | CR201_G0015864 | EPB41 isoform 1. (655 aa) |
| | KDF1 | KDF1 isoform 1. (395 aa) |
| | CNKSR1 | CNKSR1 isoform 2. (720 aa) |
| | CR201_G0025573 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (529 aa) |
| | MPP7 | MPP7 isoform 1; Belongs to the MAGUK family. (504 aa) |
| | PARD3 | PARD3 isoform 5. (1353 aa) |
| | VCL | VCL isoform 2. (1134 aa) |
| | STOX1 | STOX1 isoform 1. (989 aa) |
| | EXOC6 | Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (797 aa) |
| | ACTR1A | Actin related protein 1A. (376 aa) |
| | ADD3 | ADD3 isoform 3. (706 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (656 aa) |
| | CTBP2 | CTBP2 isoform 10. (985 aa) |
| | GLRX3 | GLRX3 isoform 1. (335 aa) |
| | CTTN | CTTN isoform 1. (508 aa) |
| | RHOD | Ras homolog family member D. (210 aa) |
| | SPTBN2 | Spectrin beta chain; Belongs to the spectrin family. (2389 aa) |
| | ENSPPYP00000003496 | annotation not available (383 aa) |
| | CTNND1 | CTNND1 isoform 19. (968 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (604 aa) |
| | INSC | INSC isoform 1. (579 aa) |
| | DENND2B | Suppression of tumorigenicity 5. (1137 aa) |
| | ARFIP2 | ARFIP2 isoform 2. (342 aa) |
| | STIM1 | Stromal interaction molecule 1. (685 aa) |
| | RHOG | Ras homolog family member G. (191 aa) |
| | NUMA1 | Nuclear mitotic apparatus protein 1. (2114 aa) |
| | CR201_G0023224 | MYO7A isoform 2. (1350 aa) |
| | RDX | RDX isoform 3. (604 aa) |
| | PHLDB1 | PHLDB1 isoform 1. (1423 aa) |
| | C2CD2L | C2CD2L isoform 1. (653 aa) |
| | ARHGAP32 | ARHGAP32 isoform 3. (533 aa) |
| | ENSPPYP00000004797 | annotation not available (276 aa) |
| | EPS8 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] (824 aa) |
| | CAPZA3 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa) |
| | GYS2 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa) |
| | C2CD5 | C2 domain-containing protein 5; Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM. (1029 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | RND1 | Rho family GTPase 1. (232 aa) |
| | BIN2 | BIN2 isoform 2. (565 aa) |
| | MYO1A | MYO1A isoform 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (827 aa) |
| | OSBPL8 | Oxysterol-binding protein; Belongs to the OSBP family. (889 aa) |
| | RIC8B | RIC8 guanine nucleotide exchange factor B. (560 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (434 aa) |
| | TRPV4 | TRPV4 isoform 2; Belongs to the transient receptor (TC 1.A.4) family. (699 aa) |
| | CR201_G0000922 | PXN isoform 2; Belongs to the paxillin family. (381 aa) |
| | CR201_G0000897 | CABP1 isoform 4. (202 aa) |
| | RHOF | RHOF isoform 5. (210 aa) |
| | HIP1R | HIP1R isoform 1. (1038 aa) |
| | FRY | FRY isoform 3. (3017 aa) |
| | TRPC4 | TRPC4 isoform 8. (893 aa) |
| | ENSPPYP00000006126 | annotation not available (543 aa) |
| | ARHGEF7 | ARHGEF7 isoform 7. (803 aa) |
| | STXBP6 | STXBP6 isoform 1. (179 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (912 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | FERMT2 | FERMT2 isoform 1. (623 aa) |
| | EXOC5 | EXOC5 isoform 1. (710 aa) |
| | CR201_G0009827 | Spectrin beta chain; Belongs to the spectrin family. (1818 aa) |
| | ACTN1 | ACTN1 isoform 1. (980 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] (463 aa) |
| | EXOC3L4 | EXOC3L4 isoform 4. (747 aa) |
| | CR201_G0039122 | TNFAIP2 isoform 1. (568 aa) |
| | SPTBN5 | SPTBN5 isoform 1. (3674 aa) |
| | EPB42 | EPB42 isoform 1. (721 aa) |
| | FLOT1 | Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa) |
| | ENSPPYP00000007360 | annotation not available (418 aa) |
| | UNC13C | UNC13C isoform 1. (1180 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase. (937 aa) |
| | ENSPPYP00000007380 | annotation not available (435 aa) |
| | MYO1E | MYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1109 aa) |
| | CR201_G0042177 | CIB2 isoform 1. (346 aa) |
| | AKAP13 | AKAP13 isoform 5. (2833 aa) |
| | IQGAP1 | IQGAP1 isoform 1. (1656 aa) |
| | CR201_G0054585 | AXIN1 isoform 6. (551 aa) |
| | OR2C1 | Olfactory receptor. (312 aa) |
| | SEPTIN12 | SEPT12 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (319 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (445 aa) |
| | EXOC3L1 | EXOC3L1 isoform 1. (746 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (346 aa) |
| | MTSS1L | MTSS1L isoform 1. (591 aa) |
| | COTL1 | COTL1 isoform 1. (116 aa) |
| | SPIRE2 | SPIRE2 isoform 1. (435 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (118 aa) |
| | FGF1 | Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with int [...] (155 aa) |
| | DLG4 | DLG4 isoform 3; Belongs to the MAGUK family. (690 aa) |
| | MYH10 | Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa) |
| | LLGL1 | LLGL1 isoform 2. (1051 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa) |
| | MYO1D | MYO1D isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa) |
| | SEPTIN4 | C17orf47 isoform 1. (570 aa) |
| | SEPTIN4-2 | Septin-4; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity). (478 aa) |
| | FMNL1 | FMNL1 isoform 2. (691 aa) |
| | SLC4A1 | Anion exchange protein. (852 aa) |
| | RND2 | RND2 isoform 1. (193 aa) |
| | KRT19 | Keratin, type I cytoskeletal 19; Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity); Belongs to the intermediate filament family. (400 aa) |
| | LASP1 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). (279 aa) |
| | EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (732 aa) |
| | CR201_G0021476 | SEPT9 isoform 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (273 aa) |
| | RAC3 | RAC3 isoform 1. (192 aa) |
| | SEPT9 | SEPT9 isoform 29; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (186 aa) |
| | PPP1R9B | PPP1R9B isoform 1. (729 aa) |
| | ENSPPYP00000010034 | annotation not available (342 aa) |
| | SPIRE1 | SPIRE1 isoform 2. (583 aa) |
| | MYL12B | Myosin light chain 12B. (172 aa) |
| | MYO5B | T0098307 isoform 1. (1849 aa) |
| | MISP | Mitotic interactor and substrate of PLK1; Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytospkeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus (By similarity); Belongs to the MISP family. (679 aa) |
| | CSNK1G2 | Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (415 aa) |
| | CR201_G0044246 | TLE6 isoform 2. (373 aa) |
| | ANKRD24 | ANKRD24 isoform 1. (1132 aa) |
| | TRIP10 | Cdc42-interacting protein 4; Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Also acts as a link between CDC42 signaling and regulation of the actin cytoskeleton. Binds to lipids such as phosphatidylinositol 4,5- bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization in the vicinity of membrane tubules by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization and dynamin may promote the fission of membrane tubules [...] (601 aa) |
| | GIPC1 | GIPC PDZ domain containing family member 1. (333 aa) |
| | TPM4 | TPM4 isoform 4; Belongs to the tropomyosin family. (260 aa) |
| | MYO9B | MYO9B isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2099 aa) |
| | UNC13A | UNC13A isoform 4. (1518 aa) |
| | RYR1 | RYR1 isoform 2. (4656 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CR201_G0043999 | SPTBN4 isoform 1. (2409 aa) |
| | ENSPPYP00000011257 | annotation not available (176 aa) |
| | PHLDB3 | PHLDB3 isoform 2. (396 aa) |
| | EXOC3L2 | EXOC3L2 isoform 1. (408 aa) |
| | PLA2G4C | Phospholipase A2 group IVC. (542 aa) |
| | PPFIA3 | PPFIA3 isoform 1. (1047 aa) |
| | KCNC3 | KCNC3 isoform 4; Belongs to the potassium channel family. (651 aa) |
| | MYADM | Myeloid-associated differentiation marker. (322 aa) |
| | NLRP5 | NLRP5 isoform 3. (1197 aa) |
| | ENSPPYP00000011868 | annotation not available (149 aa) |
| | EXOC8 | EXOC8 isoform 1. (728 aa) |
| | RHOC-2 | RHOA isoform 3. (169 aa) |
| | BFSP1 | BFSP1 isoform 2; Belongs to the intermediate filament family. (665 aa) |
| | DSTN | Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa) |
| | MAPRE1 | Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, a [...] (314 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (849 aa) |
| | MYL9 | Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. (172 aa) |
| | PARD6B | Par-6 family cell polarity regulator beta. (372 aa) |
| | CTSZ | CTSZ isoform 1; Belongs to the peptidase C1 family. (448 aa) |
| | MICAL3 | MICAL3 isoform 13. (948 aa) |
| | SEPT5 | SEPT5 isoform 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (256 aa) |
| | NF2 | Neurofibromin 2. (590 aa) |
| | MYH9 | MYH9 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1959 aa) |
| | PVALB | PVALB isoform 1; Belongs to the parvalbumin family. (110 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | SEPT3 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (326 aa) |
| | FABP1 | Fatty acid binding protein 1. (127 aa) |
| | RTKN | RTKN isoform 7. (550 aa) |
| | CR201_G0003005 | T0009947 isoform 1. (1278 aa) |
| | EXOC6B | Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (810 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2342 aa) |
| | PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa) |
| | NRBP1 | Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (573 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (129 aa) |
| | FAM110C | Family with sequence similarity 110 member C. (321 aa) |
| | CR201_G0017951 | GYPC isoform 2. (119 aa) |
| | CLASP1 | CLASP1 isoform 3. (1537 aa) |
| | ERMN | Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity). (284 aa) |
| | CYTIP | CYTIP isoform 4. (335 aa) |
| | PJVK | DFNB59 isoform 1. (352 aa) |
| | PARD3B | Partitioning defective 3 homolog B isoform X1. (1026 aa) |
| | NCL | Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats (By similarity). (713 aa) |
| | MLPH | MLPH isoform 1. (553 aa) |
| | SEPTIN2 | Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar- shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis [...] (361 aa) |
| | CR201_G0017077 | GAD1 isoform 11. (163 aa) |
| | GAD1 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (388 aa) |
| | HCLS1 | HCLS1 isoform 5. (513 aa) |
| | PHLDB2 | Pleckstrin homology-like domain family B member 2 isoform X2. (1280 aa) |
| | FLNB | FLNB isoform 3. (2536 aa) |
| | ERC2 | ERC2 isoform 1. (914 aa) |
| | BSN | BSN isoform 1. (3926 aa) |
| | RHOA | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] (196 aa) |
| | CR201_G0006350 | TRAK1 isoform 1. (691 aa) |
| | CTNNB1 | CTNNB1 isoform 2. (781 aa) |
| | MYRIP | MYRIP isoform 1. (858 aa) |
| | CLASP2 | CLASP2 isoform 2. (1505 aa) |
| | BFSP2 | BFSP2 isoform 3; Belongs to the intermediate filament family. (443 aa) |
| | PLS1 | PLS1 isoform 1. (631 aa) |
| | ECT2 | ECT2 isoform 4. (913 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (429 aa) |
| | MAEA | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] (393 aa) |
| | CR201_G0040849 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (628 aa) |
| | WDR1 | WDR1 isoform 1. (606 aa) |
| | MED28 | Mediator complex subunit 28. (178 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | FRYL | FRYL isoform 1. (2955 aa) |
| | EXOC1 | EXOC1 isoform 1. (912 aa) |
| | CR201_G0043222 | EXOC1L isoform 1. (88 aa) |
| | SHROOM3 | SHROOM3 isoform 1. (1995 aa) |
| | SEPTIN11 | Septin-11; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). (435 aa) |
| | PKD2 | PKD2 isoform 1. (968 aa) |
| | FABP2 | Fatty acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | FGB | FGB isoform 1. (491 aa) |
| | GUCY1B1 | GUCY1B3 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa) |
| | EXOC3 | EXOC3 isoform 1. (745 aa) |
| | MYO10 | MYO10 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2027 aa) |
| | RAI14 | RAI14 isoform 10. (980 aa) |
| | RHOBTB3 | RHOBTB3 isoform 7. (548 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa) |
| | SEPTIN8 | SEPT8 isoform 13; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (442 aa) |
| | SHROOM1 | Shroom family member 1. (852 aa) |
| | FCHSD1 | FCHSD1 isoform 1. (685 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (221 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1088 aa) |
| | DCTN4 | Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton (By similarity). (460 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa) |
| | DBN1 | DBN1 isoform 4. (632 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa) |
| | ENSPPYP00000018104 | annotation not available (312 aa) |
| | NEDD9 | NEDD9 isoform 1. (834 aa) |
| | CLIC5 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (205 aa) |
| | DST | DST isoform 3. (5421 aa) |
| | RIMS1 | RIMS1 isoform 16. (1644 aa) |
| | KHDC3L | KH domain containing 3 like, subcortical maternal complex member. (217 aa) |
| | OOEP | OOEP isoform 2. (94 aa) |
| | MYO6 | MYO6 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (331 aa) |
| | EPB41L2 | EPB41L2 isoform 10. (917 aa) |
| | CCN2 | Cellular communication network factor 2. (349 aa) |
| | UTRN | UTRN isoform 2. (3433 aa) |
| | AKAP12 | AKAP12 isoform 1. (1783 aa) |
| | EZR | EZR isoform 1. (586 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) |
| | FSCN1 | FSCN1 isoform 3. (444 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | SEPTIN14 | SEPT14 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (415 aa) |
| | DBNL | DBNL isoform 9. (430 aa) |
| | ANLN | ANLN isoform 2. (1089 aa) |
| | SEPTIN7 | Septin-7; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). (384 aa) |
| | SCIN | SCIN isoform 3. (715 aa) |
| | CR201_G0010042 | PPP1R9A isoform 2. (1098 aa) |
| | CR201_G0018159 | PCLO isoform 5. (356 aa) |
| | GNAI1 | Guanine nucleotide-binding protein G(i) subunit alpha-1. (302 aa) |
| | CAV1 | Caveolin-1; Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt [...] (178 aa) |
| | CAPZA2 | F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa) |
| | CTTNBP2 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. (1663 aa) |
| | WASL | WASL isoform 1. (505 aa) |
| | MKLN1 | Muskelin; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity). Required for internalization of the GABA receptor GABRA1 from the cell membrane via endosomes and subsequent GABRA1 degradation. Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1 (By similarity). (700 aa) |
| | EXOC4 | EXOC4 isoform 2. (974 aa) |
| | CALD1 | CALD1 isoform 4. (792 aa) |
| | ENSPPYP00000020410 | annotation not available (346 aa) |
| | ENSPPYP00000020465 | Septin-7-like. (329 aa) |
| | ENSPPYP00000020469 | annotation not available (241 aa) |
| | LANCL2 | LANCL2 isoform 1. (450 aa) |
| | ENSPPYP00000020478 | LOW QUALITY PROTEIN: septin-7-like. (273 aa) |
| | DLC1 | DLC1 isoform 1. (1515 aa) |
| | DMTN | Dematin; Membrane-cytoskeleton-associated protein with F-actin-binding activity that induces F-actin bundles formation and stabilization. Its F-actin-bundling activity is reversibly regulated upon its phosphorylation by the cAMP-dependent protein kinase A (PKA). Binds to the erythrocyte membrane glucose transporter-1 SLC2A1/GLUT1, and hence stabilizes and attaches the spectrin-actin network to the erythrocytic plasma membrane. Plays a role in maintaining the functional integrity of PKA-activated erythrocyte shape and the membrane mechanical properties. Plays also a role as a modulator [...] (405 aa) |
| | PDLIM2 | PDZ and LIM domain protein 1/2/3/4. (366 aa) |
| | RHOBTB2 | RHOBTB2 isoform 4. (734 aa) |
| | PTK2B | PTK2B isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | ASPH | ASPH isoform 1. (837 aa) |
| | RIMS2 | Regulating synaptic membrane exocytosis 2. (1163 aa) |
| | PTK2 | PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa) |
| | ARC | Activity regulated cytoskeleton associated protein. (396 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (651 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa) |
| | UNC13B | UNC13B isoform 5. (1610 aa) |
| | AQP7 | AQP7 isoform 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (198 aa) |
| | TMOD1 | TMOD1 isoform 1. (359 aa) |
| | CTNNAL1 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). (734 aa) |
| | GSN | GSN isoform 1. (732 aa) |
| | SPTAN1 | SPTAN1 isoform 10. (2538 aa) |
| | FNBP1 | FNBP1 isoform 4. (692 aa) |
| | TSC1 | TSC1 isoform 8. (1157 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | SAPCD2 | SAPCD2 isoform 1. (392 aa) |
| | NSMF | NSMF isoform 4. (474 aa) |
| | ENSPPYP00000022364 | annotation not available (138 aa) |
| | SHROOM2 | SHROOM2 isoform 1. (1569 aa) |
| | DMD | DMD isoform 3. (3618 aa) |
| | SEPTIN6 | SEPT6 isoform 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (422 aa) |
| | ARHGAP36 | Rho GTPase activating protein 36. (547 aa) |
| | ENSPPYP00000023282 | annotation not available (191 aa) |
| | PDZD4 | PDZD4 isoform 1. (673 aa) |
| | FLNA | FLNA isoform 7. (2647 aa) |
| | MPP1 | 55 kDa erythrocyte membrane protein; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). Belongs to the MAGUK family. (466 aa) |
| | SHROOM4 | SHROOM4 isoform 1. (1498 aa) |
| | ACTN3 | Actinin alpha 2/3. (388 aa) |
| | COBL | COBL isoform 1. (1260 aa) |
| | RASAL3 | RASAL3 isoform 1. (419 aa) |
| | SNX9 | Sorting nexin. (618 aa) |
| | ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1120 aa) |
| | SEPT1 | SEPT1 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (332 aa) |
