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| | CBARP | CBARP isoform 1. (313 aa) |
| | DISC1 | DISC1 scaffold protein. (840 aa) |
| | SNAP47 | SNAP47 isoform 1. (459 aa) |
| | SYT2 | SYT2 isoform 1. (359 aa) |
| | VAMP4 | VAMP4 isoform 1. (134 aa) |
| | NCSTN | NCSTN isoform 1. (639 aa) |
| | SYT11 | SYT11 isoform 1. (388 aa) |
| | RAB13 | RAB13 isoform 2. (203 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | APH1A | Aph-1 homolog A, gamma-secretase subunit. (265 aa) |
| | VPS45 | Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (570 aa) |
| | SV2A | Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). (637 aa) |
| | NGF | NGF isoform 1; Belongs to the NGF-beta family. (294 aa) |
| | SYT6 | SYT6 isoform 1. (509 aa) |
| | SLC6A17 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (729 aa) |
| | SYPL2 | Synaptophysin like 2. (272 aa) |
| | CR201_G0020056 | BTBD8 isoform 2. (438 aa) |
| | PDE4B | Phosphodiesterase. (736 aa) |
| | RAB3B | RAB3B, member RAS oncogene family. (219 aa) |
| | SLC6A9 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (652 aa) |
| | PPT1 | Palmitoyl-protein thioesterase 1. (306 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | KIF1B | KIF1B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1790 aa) |
| | TPRG1L | Tumor protein p63 regulated 1 like. (272 aa) |
| | GAD2 | GAD2 isoform 1. (545 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (217 aa) |
| | SLC18A2 | Solute carrier family 18 member A2. (514 aa) |
| | SYT8 | SYT8 isoform 4. (397 aa) |
| | TH | TH isoform 6. (522 aa) |
| | SYT12 | SYT12 isoform 1. (421 aa) |
| | SYT7 | SYT7 isoform 1. (400 aa) |
| | STX3 | STX3 isoform 3; Belongs to the syntaxin family. (289 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa) |
| | PICALM | PICALM isoform 11. (686 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa) |
| | TRAPPC4 | Trafficking protein particle complex subunit 4; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (219 aa) |
| | ENSPPYP00000004631 | Kin of IRRE-like protein 3. (419 aa) |
| | CR201_G0026159 | ABCC8 isoform 10. (685 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa) |
| | VAMP1 | Vesicle associated membrane protein 1. (118 aa) |
| | BORCS5 | BLOC-1 related complex subunit 5. (196 aa) |
| | DNM1L | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (686 aa) |
| | SLC4A8 | Anion exchange protein. (1093 aa) |
| | SYT1 | Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] (377 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1173 aa) |
| | SLC17A8 | Solute carrier family 17 member 8. (589 aa) |
| | SVOP | Synaptic vesicle 2-related protein. (355 aa) |
| | RAB35 | RAB35, member RAS oncogene family. (201 aa) |
| | STX2 | STX2 isoform 2; Belongs to the syntaxin family. (263 aa) |
| | TRIM9 | TRIM9 isoform 1. (807 aa) |
| | RAB15 | RAB15 isoform 2. (207 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | STON2 | STON2 isoform 2; Belongs to the Stoned B family. (861 aa) |
| | APBA2 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta (By similarity). (749 aa) |
| | ENSPPYP00000007360 | annotation not available (418 aa) |
| | UNC13C | UNC13C isoform 1. (1180 aa) |
| | SCAMP5 | Secretory carrier-associated membrane protein 5; Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity). (240 aa) |
| | SV2B | Synaptic vesicle glycoprotein 2B. (683 aa) |
| | MCTP2 | Multiple C2 and transmembrane domain containing 2. (878 aa) |
| | CR201_G0021500 | Synaptogyrin. (223 aa) |
| | RAB40C | RAB40C, member RAS oncogene family. (281 aa) |
| | SYNGR3 | Synaptogyrin. (196 aa) |
| | RAB26 | RAB26 isoform 1. (290 aa) |
| | ATP6V0C | V-type H+-transporting ATPase 16kDa proteolipid subunit. (128 aa) |
| | ROGDI | Protein rogdi homolog; Belongs to the rogdi family. (287 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | CLN3 | Battenin. (438 aa) |
| | DOC2A | Double C2-like domain-containing protein. (398 aa) |
| | PRRT2 | Proline-rich transmembrane protein 2; As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. (340 aa) |
| | STX1B | STX1B isoform 1; Belongs to the syntaxin family. (590 aa) |
| | STX4 | STX4 isoform 4; Belongs to the syntaxin family. (296 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa) |
| | C16orf70 | Chromosome 16 open reading frame 70. (422 aa) |
| | ZNRF1 | Zinc and ring finger 1. (227 aa) |
| | DLG4 | DLG4 isoform 3; Belongs to the MAGUK family. (690 aa) |
| | VAMP2 | VAMP2 isoform 2. (116 aa) |
| | RNF112 | RNF112 isoform 1. (632 aa) |
| | ATP6V0A1 | V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). (862 aa) |
| | HCRT | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa) |
| | HAP1 | HAP1 isoform 2. (662 aa) |
| | SYNGR2 | Synaptogyrin. (245 aa) |
| | RAB40B | RAB40B, member RAS oncogene family. (278 aa) |
| | DOC2B | DOC2B isoform 2. (301 aa) |
| | RAB12 | RAB12 isoform 1. (340 aa) |
| | SYT4 | SYT4 isoform 1. (425 aa) |
| | RAB27B | RAB27B, member RAS oncogene family. (218 aa) |
| | PTPRS | PTPRS isoform 2. (1616 aa) |
| | RAB11B | RAB11B, member RAS oncogene family. (218 aa) |
| | RAB3D | RAB3D isoform 1. (194 aa) |
| | STX10 | STX10 isoform 6; Belongs to the syntaxin family. (249 aa) |
| | GIPC1 | GIPC PDZ domain containing family member 1. (333 aa) |
| | UNC13A | UNC13A isoform 4. (1518 aa) |
| | RAB3A | Ras-related protein Rab-3A. (203 aa) |
| | RABAC1 | PRA1 family protein. (185 aa) |
| | SYNGR4 | Synaptogyrin. (234 aa) |
| | ENSPPYP00000011451 | annotation not available (257 aa) |
| | NTF4 | Neurotrophin 4. (210 aa) |
| | SLC17A7 | SLC17A7 isoform 1. (539 aa) |
| | SYT5 | SYT5 isoform 2. (386 aa) |
| | BRSK1 | BRSK1 isoform 1. (680 aa) |
| | TRIM67 | TRIM67 isoform 3. (409 aa) |
| | LAMP5 | Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain; Belongs to the LAMP family. (261 aa) |
| | SNAP25 | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. (206 aa) |
| | SYNDIG1 | SYNDIG1 isoform 2. (254 aa) |
| | TMEM230 | Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles. Belongs to the TMEM134/TMEM230 family. (120 aa) |
| | BCL2L1 | BCL2L1 isoform 2. (233 aa) |
| | SLC32A1 | SLC32A1 isoform 1. (527 aa) |
| | STX16 | STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa) |
| | DNAJC5 | DnaJ heat shock protein family (Hsp40) member C5. (198 aa) |
| | APP | APP isoform 3. (736 aa) |
| | ATP6V1E1 | ATP6V1E1 isoform 1. (203 aa) |
| | SEPT5 | SEPT5 isoform 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (256 aa) |
| | SYN3 | SYN3 isoform 1. (580 aa) |
| | SYNGR1 | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short- term and long-term synaptic plasticity (By similarity). Belongs to the synaptogyrin family. (654 aa) |
| | ATP6V1B1 | V-type proton ATPase subunit B, brain isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (509 aa) |
| | STON1 | STON1-GTF2A1L isoform 4; Belongs to the Stoned B family. (734 aa) |
| | SLC30A3 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (481 aa) |
| | OTOF | OTOF isoform 2. (1545 aa) |
| | SEMA4C | SEMA4C isoform 1; Belongs to the semaphorin family. (746 aa) |
| | BIN1 | BIN1 isoform 9. (517 aa) |
| | TMEM163 | TMEM163 isoform 1. (290 aa) |
| | SLC40A1 | Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (572 aa) |
| | MFF | MFF isoform 4. (328 aa) |
| | IQSEC1 | IQSEC1 isoform 4. (949 aa) |
| | SYN2 | SYN2 isoform 1. (488 aa) |
| | SYNPR | SYNPR isoform 2. (265 aa) |
| | BSN | BSN isoform 1. (3926 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | MME | Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa) |
| | WFS1 | WFS1 isoform 1. (964 aa) |
| | COPS4 | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] (406 aa) |
| | SLC9B2 | Sodium/hydrogen exchanger 9B2; Na+/H+ antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane. Contributes to the regulation of intracellular pH, Na(+) content and organellar volume. Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells. Involved in sperm motility and fertility. It is controversial whether SLC9B2 plays a role in osteoclast differentiation or not (By similarity). (509 aa) |
| | RAB3C | RAB3C, member RAS oncogene family. (227 aa) |
| | SV2C | SV2C isoform 2. (727 aa) |
| | SCAMP1 | Secretory carrier-associated membrane protein. (338 aa) |
| | MCTP1 | MCTP1 isoform 5. (774 aa) |
| | SNCAIP | SNCAIP isoform 16. (861 aa) |
| | SEPTIN8 | SEPT8 isoform 13; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (442 aa) |
| | GRIA1 | GRIA1 isoform 7. (888 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa) |
| | DTNBP1 | DTNBP1 isoform 1. (351 aa) |
| | CR201_G0042455 | GABBR1 isoform 2. (710 aa) |
| | ATP6V1G2 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | PRRT1 | Proline rich transmembrane protein 1. (306 aa) |
| | SLC17A5 | SLC17A5 isoform 1. (453 aa) |
| | SNAP91 | SNAP91 isoform 3. (908 aa) |
| | STX11 | STX11 isoform 1; Belongs to the syntaxin family. (287 aa) |
| | STXBP5 | STXBP5 isoform 4. (1112 aa) |
| | STX1A | Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...] (259 aa) |
| | DDC | DDC isoform 1. (491 aa) |
| | AMPH | AMPH isoform 1. (695 aa) |
| | ICA1 | ICA1 isoform 12. (483 aa) |
| | ATP6V1F | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa) |
| | PTPRN2 | PTPRN2 isoform 4. (930 aa) |
| | SYPL1 | Synaptophysin like 1. (259 aa) |
| | SLC18A1 | SLC18A1 isoform 2. (493 aa) |
| | ATP6V1B2 | V-type proton ATPase subunit B, brain isoform. (278 aa) |
| | LGI3 | Leucine rich repeat LGI family member 3. (548 aa) |
| | PENK | PENK isoform 3. (267 aa) |
| | COPS5 | COP9 signalosome subunit 5. (334 aa) |
| | ATP6V1C1 | V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (382 aa) |
| | KCNK9 | Potassium channel subfamily K member. (617 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa) |
| | UNC13B | UNC13B isoform 5. (1610 aa) |
| | APBA1 | APBA1 isoform 1. (787 aa) |
| | SLC2A8 | SLC2A8 isoform 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa) |
| | TOR1A | Torsin. (364 aa) |
| | GRIN1 | GRIN1 isoform 3. (887 aa) |
| | DNM1P50 | Dynamin-1. (67 aa) |
| | CLCN4 | Chloride channel protein. (760 aa) |
| | DMD | DMD isoform 3. (3618 aa) |
| | ATP6AP2 | Renin receptor extracellular fragment; Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton- transporting vacuolar (V)-ATPase protein pump. May mediate renin- dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity). Probably by controlling the assembly of the V- ATPase pump and thus the acidification of the endo-lysosomal system, plays a [...] (350 aa) |
| | CDK16 | CDK16 isoform 3. (496 aa) |
| | SYN1 | SYN1 isoform 2. (645 aa) |
| | SYP | SYP isoform 1. (313 aa) |
| | SEPTIN6 | SEPT6 isoform 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (422 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (475 aa) |
| | TMED9 | Transmembrane p24 trafficking protein 9. (235 aa) |
| | SLC17A6 | Vesicular glutamate transporter 2. (360 aa) |
| | LRRK2 | LRRK2 isoform 3. (1560 aa) |
| | DMXL2 | DMXL2 isoform 3. (2812 aa) |
| | CPLX3 | CPLX3 isoform 1. (158 aa) |
| | SEPT1 | SEPT1 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (332 aa) |
| | SYT9 | SYT9 isoform 2. (173 aa) |
| | ENSPPYP00000024575 | BTB/POZ domain-containing protein 8. (1022 aa) |
