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| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | MED24 | MED24 isoform 12. (1054 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...] (1586 aa) |
| | DDX5 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] (614 aa) |
| | CR201_G0024013 | WIPI1 isoform 2. (251 aa) |
| | WBP2 | WW domain binding protein 2. (261 aa) |
| | BCAS3 | BCAS3 isoform 8. (841 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2100 aa) |
| | ENSPPYP00000010327 | annotation not available (526 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (725 aa) |
| | SMARCA4 | SMARCA4 isoform 2. (1647 aa) |
| | STRN | STRN isoform 1. (780 aa) |
| | CTNNB1 | CTNNB1 isoform 2. (781 aa) |
| | FOXL2 | FOXL2 isoform 1. (376 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | TRIP4 | TRIP4 isoform 2. (581 aa) |
| | SNW1 | SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, [...] (538 aa) |
| | SLIRP | SRA stem-loop-interacting RNA-binding protein, mitochondrial; RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation (By similarity). (109 aa) |
| | CR201_G0009767 | HIF1A isoform 5. (735 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa) |
| | FLT3 | FLT3 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | RNF6 | RNF6 isoform 2. (685 aa) |
| | NCOR2 | NCOR2 isoform 6. (2461 aa) |
| | CCDC62 | CCDC62 isoform 1. (614 aa) |
| | OASL | 2'-5'-oligoadenylate synthetase like. (514 aa) |
| | DDX54 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (883 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (586 aa) |
| | NR1H4 | NR1H4 isoform 5. (475 aa) |
| | GRIP1 | GRIP1 isoform 2. (1016 aa) |
| | BAZ2A | BAZ2A isoform 2. (1912 aa) |
| | RARG | RARG isoform 5. (469 aa) |
| | VDR | VDR isoform 4. (486 aa) |
| | RERG | RAS like estrogen regulated growth inhibitor. (199 aa) |
| | FKBP4 | Peptidylprolyl isomerase. (459 aa) |
| | TRIM68 | TRIM68 isoform 1. (344 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa) |
| | GTF2H1 | General transcription factor IIH subunit 1. (548 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (593 aa) |
| | CR201_G0012702-2 | TACC2 isoform 5. (1307 aa) |
| | CTBP2 | CTBP2 isoform 10. (985 aa) |
| | CR201_G0012702 | TACC2 isoform 1. (1094 aa) |
| | CR201_G0012836 | TCF7L2 isoform 2. (430 aa) |
| | MMS19 | MMS19 isoform 3. (1030 aa) |
| | LCOR | LCOR isoform 2. (1557 aa) |
| | NRBF2 | Nuclear receptor-binding factor 2; May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro) (By similarity); Belongs to the NRBF family. (287 aa) |
| | JMJD1C | Jumonji domain containing 1C. (2540 aa) |
| | SIRT1 | SIRT1 isoform 1. (746 aa) |
| | LOC100435863 | HMGA1 isoform 3. (95 aa) |
| | PARK7 | PARK7 isoform 1. (189 aa) |
| | SRARP | Steroid receptor associated and regulated protein. (169 aa) |
| | PADI2 | Peptidyl arginine deiminase 2. (665 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | ARID1A | ARID1A isoform 1. (2006 aa) |
| | NR0B2 | Nuclear receptor subfamily 0 group B member 2. (257 aa) |
| | CR201_G0015676 | THRAP3 isoform 1. (560 aa) |
| | GTF2B | Transcription initiation factor IIB; General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II- TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter [...] (373 aa) |
| | LRIF1 | LRIF1 isoform 1. (742 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (972 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | PPID | Peptidylprolyl isomerase D. (370 aa) |
| | ISL1 | ISL1 isoform 1. (349 aa) |
| | ZNF366 | ZNF366 isoform 1. (744 aa) |
| | CR201_G0017535 | BRD8 isoform 7. (969 aa) |
| | TAF7 | Transcription initiation factor TFIID subunit 7; Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF7 family. (349 aa) |
| | RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) |
| | PPARGC1B | PPARGC1B isoform 1. (1022 aa) |
| | NSD1 | NSD1 isoform 2. (2427 aa) |
| | TRERF1 | TRERF1 isoform 4. (1115 aa) |
| | NCOA7 | NCOA7 isoform 1. (900 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1130 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | DAXX | Death domain associated protein. (743 aa) |
| | BUD31 | BUD31 isoform 1. (144 aa) |
| | TRIP6 | Thyroid hormone receptor interactor 6. (476 aa) |
| | TRIM24 | TRIM24 isoform 1. (1050 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa) |
| | NKX3-1 | NKX3-1 isoform 1. (236 aa) |
| | TACC1 | TACC1 isoform 1. (789 aa) |
| | DCAF13 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. (445 aa) |
| | MED30 | Mediator complex subunit 30. (178 aa) |
| | KDM4C | Lysine demethylase 4C. (1056 aa) |
| | NR4A3 | NR4A3 isoform 1. (626 aa) |
| | RXRA | RXRA isoform 2. (456 aa) |
| | ENSPPYP00000022364 | annotation not available (138 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (470 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1418 aa) |
| | MED12 | MED12 isoform 3. (2178 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1755 aa) |
| | TAF7L | TAF7L isoform 2. (376 aa) |
| | HMGA1 | HMGA1 isoform 1. (104 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1464 aa) |
| | ENSPPYP00000024141 | annotation not available (55 aa) |
| | FOXH1 | FOXH1 isoform 1. (366 aa) |
| | ENSPPYP00000024510 | annotation not available (85 aa) |
| | NR4A1 | NR4A1 isoform 2. (611 aa) |
| | ENSPPYP00000014053 | annotation not available (357 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1293 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2; Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity); Belongs to the nuclear hormone receptor family. (598 aa) |
| | STAT1 | Signal transducer and activator of transcription. (766 aa) |
| | TRIP12 | TRIP12 isoform 4. (2039 aa) |
| | NR1I2 | NR1I2 isoform 1. (393 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma. (477 aa) |
| | CALR | Calreticulin. (417 aa) |
| | PKN1 | PKN1 isoform 3. (943 aa) |
| | MED25 | MED25 isoform 7. (834 aa) |
| | NR1H2 | NR1H2 isoform 11. (413 aa) |
| | ZBTB7A | ZBTB7A isoform 1. (421 aa) |
| | ENSPPYP00000011868 | annotation not available (149 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1476 aa) |
| | NCOA6 | NCOA6 isoform 5. (2070 aa) |
| | SRC | Tyrosine-protein kinase. (553 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1420 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (345 aa) |
| | PRPF6 | Pre-mRNA-processing factor 6; Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. (941 aa) |
| | ENSPPYP00000012589 | Putative nuclear receptor corepressor 1-like protein NCOR1P1. (101 aa) |
| | NRIP1 | NRIP1 isoform 1. (1141 aa) |
| | PRMT2 | PRMT2 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (433 aa) |
| | CR201_G0047492 | PRAME isoform 2. (377 aa) |
| | XBP1 | X-box binding protein 1. (262 aa) |
| | GAS2L1 | GAS2L1 isoform 1. (681 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | EP300 | EP300 isoform 1. (2380 aa) |
| | ARID5A | ARID5A isoform 2. (301 aa) |
| | KDM3A | Lysine demethylase 3A. (1321 aa) |
| | TADA3 | Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity). (432 aa) |
| | FOXP1 | FOXP1 isoform 1. (677 aa) |
| | TMF1 | TMF1 isoform 1. (992 aa) |
| | DCAF1 | DCAF1 isoform 2. (1483 aa) |
| | CNOT1 | CCR4-NOT transcription complex subunit 1. (2376 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | NCOR1 | NCOR1 isoform 1. (2467 aa) |
| | STAT5B | Signal transducer and activator of transcription. (788 aa) |
