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| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa) |
| | GHR | Growth hormone receptor. (638 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (576 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (384 aa) |
| | BOD1L1 | BOD1L1 isoform 1. (3015 aa) |
| | DLG1 | DLG1 isoform 5; Belongs to the MAGUK family. (922 aa) |
| | FBXL2 | F-box/LRR-repeat protein 2; Calcium-activated substrate recognition component of the SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex, SCF(FBXL2), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Unlike many F-box proteins, FBXL2 does not seem to target phosphodegron within its substrates but rather calmodulin-binding motifs and is thereby antagonized by calmodulin. This is the case for the cyclins CCND2 and CCND3 which polyubiquitination and subsequent degradation are inhibited by calmodulin. Through CCND2 and CCND3 degrad [...] (423 aa) |
| | CTNNB1 | CTNNB1 isoform 2. (781 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma. (477 aa) |
| | DZIP3 | DZIP3 isoform 1. (1176 aa) |
| | STAT1 | Signal transducer and activator of transcription. (766 aa) |
| | SH3YL1 | SH3 domain-containing YSC84-like protein 1. (342 aa) |
| | STRN | STRN isoform 1. (780 aa) |
| | FBXO41 | FBXO41 isoform 2. (302 aa) |
| | EIF2AK3 | EIF2AK3 isoform 1. (1116 aa) |
| | ENSPPYP00000013398 | annotation not available (195 aa) |
| | PPP6R2 | PPP6R2 isoform 5. (890 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (474 aa) |
| | SFI1 | SFI1 isoform 9. (1202 aa) |
| | MTMR3 | Myotubularin related protein 3. (1198 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (130 aa) |
| | PPP1R3D | Protein phosphatase 1 regulatory subunit. (299 aa) |
| | PHACTR3 | Phosphatase and actin regulator. (518 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) |
| | STAU1 | STAU1 isoform 2. (576 aa) |
| | PTPRT | PTPRT isoform 3. (1330 aa) |
| | PPP1R16B | PPP1R16B isoform 1. (519 aa) |
| | TRPC4AP | Transient receptor potential cation channel subfamily C member 4 associated protein. (797 aa) |
| | SIRPD | Signal-regulatory protein delta. (197 aa) |
| | CR201_G0018437 | SIRPG isoform 1. (276 aa) |
| | SIRPA | SIRPA isoform 2. (503 aa) |
| | C20orf27 | Uncharacterized protein. (174 aa) |
| | PPP6R1 | PPP6R1 isoform 1. (942 aa) |
| | LOC100433990 | LILRB1 isoform 5. (649 aa) |
| | SIGLEC10 | Sialic acid binding Ig like lectin 10. (698 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] (723 aa) |
| | CD33 | CD33 isoform 3. (332 aa) |
| | VRK3 | VRK3 isoform 3. (424 aa) |
| | CR201_G0029786 | SIGLEC10 isoform 5. (275 aa) |
| | SIGLEC11 | SIGLEC11 isoform 2. (795 aa) |
| | PPP1R15A | PPP1R15A isoform 1. (676 aa) |
| | STRN4 | STRN4 isoform 4. (666 aa) |
| | STYXL1 | STYXL1 isoform 1. (303 aa) |
| | ENSPPYP00000019656 | annotation not available (239 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | SKAP2 | Src kinase-associated phosphoprotein 2; May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway (By similarity). Belongs to the SKAP family. (359 aa) |
| | CR201_G0010096 | LRRD1 isoform 1. (117 aa) |
| | MAGI2 | MAGI2 isoform 1. (1339 aa) |
| | PPP1R3A | PPP1R3A isoform 2. (1121 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1409 aa) |
| | FAM71F2 | FAM71F2 isoform 5. (309 aa) |
| | FAM71F1 | Family with sequence similarity 71 member F1. (344 aa) |
| | MTMR9 | MTMR9 isoform 1. (549 aa) |
| | PPP1R3B | Protein phosphatase 1 regulatory subunit. (285 aa) |
| | MFHAS1 | MFHAS1 isoform 1. (1001 aa) |
| | SH2D4A | SH2D4A isoform 1. (380 aa) |
| | ANK1 | Ankyrin-1 isoform X1. (1695 aa) |
| | ADCY8 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) |
| | PTK2 | PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa) |
| | PPP1R16A | PPP1R16A isoform 5. (485 aa) |
| | VCP | Transitional endoplasmic reticulum ATPase isoform X1. (806 aa) |
| | ENSPPYP00000021684 | annotation not available (884 aa) |
| | SYK | Tyrosine-protein kinase. (588 aa) |
| | STX17 | STX17 isoform 1; Belongs to the syntaxin family. (302 aa) |
| | GRIN3A | GRIN3A isoform 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1120 aa) |
| | DAB2IP | DAB2IP isoform 2. (1130 aa) |
| | PTPA | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (323 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | TPRN | TPRN isoform 2. (404 aa) |
| | MTMR4 | Myotubularin related protein 4. (1227 aa) |
| | PVRIG | PVRIG isoform 1. (326 aa) |
| | CEP192 | CEP192 isoform 7. (1925 aa) |
| | ENSPPYP00000024179 | 14-3-3 protein epsilon-like isoform X1. (173 aa) |
| | KCNN4 | KCNN4 isoform 3. (374 aa) |
| | CADM4 | CADM4 isoform 1. (368 aa) |
| | CEACAM1 | CEACAM1 isoform 2. (527 aa) |
| | CR201_G0043999 | SPTBN4 isoform 1. (2409 aa) |
| | CD22 | CD22 isoform 11. (847 aa) |
| | CR201_G0037390 | PIK3R2 isoform 1. (641 aa) |
| | JAK3 | Tyrosine-protein kinase. (1013 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | GTF2F1 | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa) |
| | BCL2 | BCL2 isoform 1. (238 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator [...] (467 aa) |
| | CDC27 | CDC27 isoform 1. (824 aa) |
| | PPP1R9B | PPP1R9B isoform 1. (729 aa) |
| | SKAP1 | SKAP1 isoform 2. (347 aa) |
| | ENSPPYP00000009928 | annotation not available (353 aa) |
| | RPS6KB1 | T0040019 isoform 1. (525 aa) |
| | PPP1R27 | PPP1R27 isoform 1. (122 aa) |
| | SPHK1 | SPHK1 isoform 7. (470 aa) |
| | GRB2 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. (217 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (357 aa) |
| | FBXL20 | FBXL20 isoform 1. (415 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1256 aa) |
| | JUP | JUP isoform 1. (670 aa) |
| | STAT3 | Signal transducer and activator of transcription. (772 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | DLG4 | DLG4 isoform 3; Belongs to the MAGUK family. (690 aa) |
| | SMTNL2 | Smoothelin like 2. (461 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | HSF4 | HSF4 isoform 10. (492 aa) |
| | CDH5 | CDH5 isoform 2; Cadherins are calcium-dependent cell adhesion proteins. (781 aa) |
| | CR201_G0034501 | C20orf27 isoform 1. (138 aa) |
| | MVP | Major vault protein; Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). (874 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) |
| | CARHSP1 | CARHSP1 isoform 14. (148 aa) |
| | TSC2 | TSC2 isoform 1. (1738 aa) |
| | SLC9A3R2 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (337 aa) |
| | AP3B2 | AP-3 complex subunit beta. (1038 aa) |
| | IQGAP1 | IQGAP1 isoform 1. (1656 aa) |
| | CSK | Tyrosine-protein kinase. (437 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | ARPP19 | ARPP19 isoform 1; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (120 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PPP1R36 | Protein phosphatase 1 regulatory subunit 36. (422 aa) |
| | AKAP5 | A-kinase anchoring protein 5. (427 aa) |
| | LGALS3 | Galectin. (309 aa) |
| | STRN3 | STRN3 isoform 2. (796 aa) |
| | MYO16 | MYO16 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1861 aa) |
| | AKAP11 | AKAP11 isoform 1. (1901 aa) |
| | FOXO1 | FOXO1 isoform 1. (654 aa) |
| | ANKLE2 | ANKLE2 isoform 1. (883 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). (755 aa) |
| | CR201_G0000922 | PXN isoform 2; Belongs to the paxillin family. (381 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (586 aa) |
| | PAWR | PAWR isoform 3. (340 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | CSRNP2 | CSRNP2 isoform 6. (497 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | SYTL2 | SYTL2 isoform 4. (935 aa) |
| | PPME1 | Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme (By similarity); Belongs to the AB hydrolase superfamily. (386 aa) |
| | SBF2 | SET binding factor 2. (1849 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (593 aa) |
| | AMBRA1 | AMBRA1 isoform 3. (1241 aa) |
| | SMTNL1 | SMTNL1 isoform 1. (456 aa) |
| | PPP1R32 | LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 32. (424 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | PPP6R3 | PPP6R3 isoform 7. (845 aa) |
| | KCNQ1 | KCNQ1 isoform 3; Belongs to the potassium channel family. (301 aa) |
| | SHOC2 | Leucine-rich repeat protein SHOC-2; Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. (582 aa) |
| | PPP1R3C | Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (438 aa) |
| | SH2D4B | SH2D4B isoform 1. (431 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | MASTL | MASTL isoform 1. (878 aa) |
| | CR201_G0044109 | RACK1 isoform 5. (346 aa) |
| | RCAN3 | RCAN family member 3. (241 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | PHACTR4 | Phosphatase and actin regulator 4; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to [...] (687 aa) |
| | LCK | Tyrosine-protein kinase. (487 aa) |
| | TCTEX1D4 | Tctex1 domain containing 4. (221 aa) |
| | MAST2 | Microtubule associated serine/threonine kinase 2. (1798 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | ENSPPYP00000001345 | annotation not available (371 aa) |
| | CTTNBP2NL | CTTNBP2 N-terminal-like protein. (638 aa) |
| | ENSA | Endosulfine alpha. (137 aa) |
| | SMG5 | SMG5 nonsense mediated mRNA decay factor. (1016 aa) |
| | FCRL3 | Fc receptor like 3. (742 aa) |
| | FCRL2 | FCRL2 isoform 2. (497 aa) |
| | FCRL6 | Fc receptor like 6. (435 aa) |
| | KIFAP3 | KIFAP3 isoform 2. (787 aa) |
| | SMG7 | SMG7 nonsense mediated mRNA decay factor. (1137 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1110 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | NEK2 | NIMA related kinase 2. (445 aa) |
| | CNST | CNST isoform 1. (690 aa) |
| | CR201_G0044109-2 | RACK1 isoform 22. (230 aa) |
| | CR201_G0009393 | PHACTR1 isoform 3. (107 aa) |
| | RACK1 | RACK1 isoform 13. (372 aa) |
| | PPP1R3F | PPP1R3F isoform 2. (798 aa) |
| | IGBP1 | Immunoglobulin binding protein 1. (339 aa) |
| | DLG3 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa) |
| | CHCHD3 | MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (227 aa) |
| | HSP90B1 | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. (773 aa) |
| | PPP1R3E | Protein phosphatase 1 regulatory subunit 3E. (279 aa) |
| | WNK1 | WNK1 isoform 4. (2694 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (158 aa) |
| | SIRPB1 | SIRPG isoform 2. (397 aa) |
| | PPP1R11 | PPP1R11 isoform 1. (104 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa) |
| | PDLIM4 | PDZ and LIM domain 4. (330 aa) |
| | SH3RF2 | SH3 domain containing ring finger 2. (729 aa) |
| | CSF1R | CSF1R isoform 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (898 aa) |
| | BOD1 | BOD1 isoform 1. (283 aa) |
| | FLT4 | FLT4 isoform 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1225 aa) |
| | ENSPPYP00000018058 | annotation not available (112 aa) |
| | PHACTR1 | Phosphatase and actin regulator. (488 aa) |
| | PPP1R10 | Protein phosphatase 1 regulatory subunit 10. (924 aa) |
| | PPP1R18 | PPP1R18 isoform 1. (614 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | SNX3 | Sorting nexin-3; Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo- selective subcomplex (CSC). May act in part as component of the SNX3- retromer complex which mediates the retrograde [...] (162 aa) |
| | ROS1 | Tyrosine-protein kinase receptor. (2341 aa) |
| | MAP3K5 | MAP3K5 isoform 1. (1327 aa) |
| | GNA12 | GNA12 isoform 1. (381 aa) |
| | CR201_G0048550 | PPP1R35 isoform 3. (127 aa) |
