STRINGSTRING
SNAP47 SNAP47 SYT2 SYT2 STX6 STX6 VAMP4 VAMP4 SYT6 SYT6 STXBP3 STXBP3 HECTD3 HECTD3 TXLNA TXLNA VAMP3 VAMP3 SYT8 SYT8 SYT12 SYT12 SYT7 SYT7 VPS11 VPS11 VAMP1 VAMP1 TPCN1 TPCN1 SCFD1 SCFD1 ENSPPYP00000007090 ENSPPYP00000007090 CR201_G0056275 CR201_G0056275 CR201_G0056473 CR201_G0056473 ENSPPYP00000007137 ENSPPYP00000007137 ENSPPYP00000007156 ENSPPYP00000007156 VPS18 VPS18 SNAP23 SNAP23 HAUS2 HAUS2 CR201_G0046277 CR201_G0046277 ENSPPYP00000007360 ENSPPYP00000007360 UNC13C UNC13C ENSPPYP00000007506 ENSPPYP00000007506 ENSPPYP00000007564 ENSPPYP00000007564 CR201_G0043294 CR201_G0043294 CR201_G0051405 CR201_G0051405 ENSPPYP00000007759 ENSPPYP00000007759 CR201_G0056251 CR201_G0056251 ENSPPYP00000007764 ENSPPYP00000007764 CR201_G0050725 CR201_G0050725 CR201_G0056481-2 CR201_G0056481-2 CR201_G0014967 CR201_G0014967 LOC100443202 LOC100443202 CR201_G0055098 CR201_G0055098 ENSPPYP00000007784 ENSPPYP00000007784 BAIAP3 BAIAP3 SYT17 SYT17 PRRT2 PRRT2 VAMP2 VAMP2 STX8 STX8 SLC6A4 SLC6A4 STXBP4 STXBP4 PTPN2 PTPN2 NAPG NAPG CPLX4 CPLX4 STXBP2 STXBP2 STX10 STX10 CR201_G0047825 CR201_G0047825 UNC13A UNC13A NAPA NAPA SYT3 SYT3 SYT5 SYT5 SNAP25 SNAP25 NAPB NAPB SNPH SNPH STX16 STX16 SNAP29 SNAP29 VPS54 VPS54 STXBP5L STXBP5L ENSPPYP00000015197 ENSPPYP00000015197 ENSPPYP00000016227 ENSPPYP00000016227 SCFD2 SCFD2 FAM172A FAM172A CPLX2 CPLX2 ENSPPYP00000018069 ENSPPYP00000018069 STX7 STX7 TXLNB TXLNB STXBP5 STXBP5 VPS52 VPS52 TMED4 TMED4 SYBU SYBU UNC13B UNC13B DAPK1 DAPK1 ABCA1 ABCA1 STXBP1 STXBP1 GOLGA2 GOLGA2 CR201_G0027499 CR201_G0027499 ABL1 ABL1 DNM1P50 DNM1P50 ENSPPYP00000022420 ENSPPYP00000022420 ENSPPYP00000022422 ENSPPYP00000022422 TXLNG TXLNG TMED9 TMED9 LRRK2 LRRK2 ENSPPYP00000024064 ENSPPYP00000024064 CPLX3 CPLX3 TMED10 TMED10 SYT9 SYT9 GOLGA8A GOLGA8A CR201_G0055953 CR201_G0055953
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNAP47SNAP47 isoform 1. (459 aa)
SYT2SYT2 isoform 1. (359 aa)
STX6Syntaxin-6; Involved in intracellular vesicle trafficking. (255 aa)
VAMP4VAMP4 isoform 1. (134 aa)
SYT6SYT6 isoform 1. (509 aa)
STXBP3STXBP3 isoform 1; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
HECTD3HECTD3 isoform 1. (722 aa)
TXLNATXLNA isoform 1. (485 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
SYT8SYT8 isoform 4. (397 aa)
SYT12SYT12 isoform 1. (421 aa)
SYT7SYT7 isoform 1. (400 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
TPCN1TPCN1 isoform 2. (798 aa)
SCFD1SCFD1 isoform 1; Belongs to the STXBP/unc-18/SEC1 family. (644 aa)
ENSPPYP00000007090annotation not available (597 aa)
CR201_G0056275Uncharacterized protein. (396 aa)
CR201_G0056473GOLGA8R isoform 1. (576 aa)
ENSPPYP00000007137annotation not available (195 aa)
ENSPPYP00000007156annotation not available (496 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
HAUS2HAUS augmin-like complex subunit 2; Belongs to the HAUS2 family. (235 aa)
CR201_G0046277Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (143 aa)
ENSPPYP00000007360annotation not available (418 aa)
UNC13CUNC13C isoform 1. (1180 aa)
ENSPPYP00000007506annotation not available (522 aa)
ENSPPYP00000007564annotation not available (279 aa)
CR201_G0043294T0153360 isoform 1. (86 aa)
CR201_G0051405GOLGA8H isoform 1. (739 aa)
ENSPPYP00000007759annotation not available (261 aa)
CR201_G0056251GOLGA8Q isoform 1. (430 aa)
ENSPPYP00000007764annotation not available (72 aa)
CR201_G0050725Uncharacterized protein. (423 aa)
CR201_G0056481-2GOLGA6L22 isoform 2. (564 aa)
CR201_G0014967GOLGA8N isoform 2. (361 aa)
LOC100443202GOLGA6D isoform 1. (686 aa)
CR201_G0055098GOLGA6L6 isoform 1. (403 aa)
ENSPPYP00000007784annotation not available (131 aa)
BAIAP3BAIAP3 isoform 3. (1072 aa)
SYT17Synaptotagmin-17; Plays a role in dendrite formation by melanocytes. Belongs to the synaptotagmin family. (473 aa)
PRRT2Proline-rich transmembrane protein 2; As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. (340 aa)
VAMP2VAMP2 isoform 2. (116 aa)
STX8STX8 isoform 2. (236 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (595 aa)
STXBP4STXBP4 isoform 1. (553 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
NAPGNAPG isoform 3. (312 aa)
CPLX4CPLX4 isoform 2. (160 aa)
STXBP2Syntaxin binding protein 2. (592 aa)
STX10STX10 isoform 6; Belongs to the syntaxin family. (249 aa)
CR201_G0047825Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1995 aa)
UNC13AUNC13A isoform 4. (1518 aa)
NAPANAPA isoform 1. (276 aa)
SYT3Synaptotagmin 3. (590 aa)
SYT5SYT5 isoform 2. (386 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. (206 aa)
NAPBNAPB isoform 4. (298 aa)
SNPHSNPH isoform 2. (535 aa)
STX16STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa)
SNAP29Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions. (258 aa)
VPS54VPS54 subunit of GARP complex. (977 aa)
STXBP5LSTXBP5L isoform 1. (1024 aa)
ENSPPYP00000015197Putative protein FAM172B. (352 aa)
ENSPPYP00000016227annotation not available (190 aa)
SCFD2SCFD2 isoform 1; Belongs to the STXBP/unc-18/SEC1 family. (684 aa)
FAM172AFamily with sequence similarity 172 member A. (416 aa)
CPLX2CPLX2 isoform 1. (134 aa)
ENSPPYP00000018069LOW QUALITY PROTEIN: golgin subfamily A member 6-like protein 2. (115 aa)
STX7Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). (261 aa)
TXLNBTXLNB isoform 1. (684 aa)
STXBP5STXBP5 isoform 4. (1112 aa)
VPS52VPS52 isoform 4. (723 aa)
TMED4Transmembrane p24 trafficking protein 4. (227 aa)
SYBUSYBU isoform 13. (648 aa)
UNC13BUNC13B isoform 5. (1610 aa)
DAPK1DAPK1 isoform 2. (1430 aa)
ABCA1ABCA1 isoform 1. (2234 aa)
STXBP1Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions (By similarity). (581 aa)
GOLGA2GOLGA2 isoform 2. (1033 aa)
CR201_G0027499ABL1 isoform 3. (48 aa)
ABL1Tyrosine-protein kinase. (948 aa)
DNM1P50Dynamin-1. (67 aa)
ENSPPYP00000022420annotation not available (560 aa)
ENSPPYP00000022422annotation not available (126 aa)
TXLNGTXLNG isoform 2. (557 aa)
TMED9Transmembrane p24 trafficking protein 9. (235 aa)
LRRK2LRRK2 isoform 3. (1560 aa)
ENSPPYP00000024064annotation not available (287 aa)
CPLX3CPLX3 isoform 1. (158 aa)
TMED10Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] (216 aa)
SYT9SYT9 isoform 2. (173 aa)
GOLGA8AGolgin subfamily A member 8A isoform X1. (69 aa)
CR201_G0055953GOLGA6L1 isoform 1. (392 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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