21 items (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DISC1	DISC1 scaffold protein. (840 aa)
	IGF2BP1	Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
	NUMBL	NUMBL isoform 1. (418 aa)
	SIX3	SIX3 isoform 1. (210 aa)
	ENSPPYP00000014984	annotation not available (349 aa)
	CEP120	Centrosomal protein 120. (986 aa)
	GLI3	GLI3 isoform 3. (1580 aa)
	PCM1	PCM1 isoform 1. (2042 aa)
	HOOK3	Protein Hook homolog 3 isoform X1. (804 aa)
	AKNA	AKNA isoform 1. (1357 aa)
	CR201_G0013169	ARX isoform 4. (297 aa)
	NUMB	NUMB endocytic adaptor protein. (651 aa)
	DCT	Dopachrome tautomerase. (519 aa)
	LHX5	LHX5 isoform 2. (402 aa)
	DIXDC1	DIX domain containing 1. (683 aa)
	EMX2	EMX2 isoform 1. (222 aa)
	FGFR2	Fibroblast growth factor receptor. (656 aa)
	CR201_G0023542	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa)
	DOCK7	DOCK7 isoform 6; Belongs to the DOCK family. (2108 aa)
	KIF14	KIF14 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1366 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0023542	EMX2	ENSPPYP00000003008	ENSPPYP00000003284	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	EMX2 isoform 1.	0.502
CR201_G0023542	FGFR2	ENSPPYP00000003008	ENSPPYP00000003165	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.959
CR201_G0023542	GLI3	ENSPPYP00000003008	ENSPPYP00000019741	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	GLI3 isoform 3.	0.467
CR201_G0023542	WNT3A	ENSPPYP00000003008	ENSPPYP00000000148	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.568
EMX2	CR201_G0023542	ENSPPYP00000003284	ENSPPYP00000003008	EMX2 isoform 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.502
FGFR2	CR201_G0023542	ENSPPYP00000003165	ENSPPYP00000003008	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.959
GLI3	CR201_G0023542	ENSPPYP00000019741	ENSPPYP00000003008	GLI3 isoform 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
GLI3	NUMBL	ENSPPYP00000019741	ENSPPYP00000011192	GLI3 isoform 3.	NUMBL isoform 1.	0.400
HOOK3	PCM1	ENSPPYP00000020818	ENSPPYP00000020606	Protein Hook homolog 3 isoform X1.	PCM1 isoform 1.	0.520
NUMB	NUMBL	ENSPPYP00000006785	ENSPPYP00000011192	NUMB endocytic adaptor protein.	NUMBL isoform 1.	0.425
NUMBL	GLI3	ENSPPYP00000011192	ENSPPYP00000019741	NUMBL isoform 1.	GLI3 isoform 3.	0.400
NUMBL	NUMB	ENSPPYP00000011192	ENSPPYP00000006785	NUMBL isoform 1.	NUMB endocytic adaptor protein.	0.425
PCM1	HOOK3	ENSPPYP00000020606	ENSPPYP00000020818	PCM1 isoform 1.	Protein Hook homolog 3 isoform X1.	0.520
WNT3A	CR201_G0023542	ENSPPYP00000000148	ENSPPYP00000003008	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.568