STRINGSTRING
PBX1 PBX1 WNT4 WNT4 ARID5B ARID5B DKK3 DKK3 WNT11 WNT11 APOA1 APOA1 ASCL1 ASCL1 SMAD3 SMAD3 STRA6 STRA6 SALL1 SALL1 ARMC5 ARMC5 NF1 NF1 SMAD4 SMAD4 INSR INSR TSPO TSPO LOC100438930 LOC100438930 CYP1B1 CYP1B1 CITED2 CITED2 CRH CRH NR5A1 NR5A1 NR0B1 NR0B1 ENSPPYP00000023994 ENSPPYP00000023994 WT1 WT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PBX1PBX homeobox 1. (430 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ARID5BARID5B isoform 1. (942 aa)
DKK3DKK3 isoform 2. (413 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). (219 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (235 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
STRA6Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...] (666 aa)
SALL1SALL1 isoform 2. (1246 aa)
ARMC5ARMC5 isoform 5. (523 aa)
NF1NF1 isoform 6. (2838 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
INSRTyrosine-protein kinase receptor. (1305 aa)
TSPOTranslocator protein. (169 aa)
LOC100438930MDK isoform 6. (143 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
CRHCRH isoform 1. (199 aa)
NR5A1NR5A1 isoform 2. (461 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
ENSPPYP00000023994annotation not available (259 aa)
WT1WT1 isoform 2. (320 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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