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| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) |
| | SEC24B | SEC24B isoform 3. (1137 aa) |
| | LRRK2 | LRRK2 isoform 3. (1560 aa) |
| | SLC17A6 | Vesicular glutamate transporter 2. (360 aa) |
| | VAMP7 | Vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] (220 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (475 aa) |
| | VMA21 | Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. (101 aa) |
| | SYTL4 | SYTL4 isoform 2. (672 aa) |
| | SYP | SYP isoform 1. (313 aa) |
| | SYN1 | SYN1 isoform 2. (645 aa) |
| | ATP6AP2 | Renin receptor extracellular fragment; Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton- transporting vacuolar (V)-ATPase protein pump. May mediate renin- dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity). Probably by controlling the assembly of the V- ATPase pump and thus the acidification of the endo-lysosomal system, plays a [...] (350 aa) |
| | DMD | DMD isoform 3. (3618 aa) |
| | AP1S2 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa) |
| | DNM1P50 | Dynamin-1. (67 aa) |
| | SEC16A | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2328 aa) |
| | DBH | DBH isoform 1. (615 aa) |
| | STX17 | STX17 isoform 1; Belongs to the syntaxin family. (302 aa) |
| | UNC13B | UNC13B isoform 5. (1610 aa) |
| | CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa) |
| | SLC30A8 | SLC30A8 isoform 3. (369 aa) |
| | ATP6V1C1 | V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (382 aa) |
| | NCALD | Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions (By similarity). Belongs to the recoverin family. (193 aa) |
| | ATP6V1B2 | V-type proton ATPase subunit B, brain isoform. (278 aa) |
| | SLC18A1 | SLC18A1 isoform 2. (493 aa) |
| | SYPL1 | Synaptophysin like 1. (259 aa) |
| | PTPRN2 | PTPRN2 isoform 4. (930 aa) |
| | ATP6V1F | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa) |
| | ICA1 | ICA1 isoform 12. (483 aa) |
| | AMPH | AMPH isoform 1. (695 aa) |
| | STX1A | Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...] (259 aa) |
| | AP1S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (245 aa) |
| | TMEM184A | TMEM184A isoform 1. (203 aa) |
| | ENSPPYP00000019362 | annotation not available (170 aa) |
| | CR201_G0055693 | HLA-B isoform 1; Belongs to the MHC class I family. (362 aa) |
| | CR201_G0016218-2 | HLA-DPA1 isoform 3. (239 aa) |
| | ENSPPYP00000019322 | annotation not available (157 aa) |
| | LOC100460187 | MHC class II protein; Belongs to the MHC class II family. (254 aa) |
| | CR201_G0042422 | HLA-G isoform 2; Belongs to the MHC class I family. (365 aa) |
| | CR201_G0016219 | HLA-DPB1 isoform 1. (283 aa) |
| | CR201_G0016218 | HLA-DPA1 isoform 1; Belongs to the MHC class II family. (260 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 2. (264 aa) |
| | ENSPPYP00000019293 | HLA class II histocompatibility antigen, DRB1-11 beta chain isoform X1. (266 aa) |
| | CR201_G0016191 | HLA-DRB5 isoform 1. (290 aa) |
| | MHC-Poab-B | MHC class I antigen; Belongs to the MHC class I family. (323 aa) |
| | CR201_G0055889 | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | ARFGEF3 | ARFGEF3 isoform 1. (1708 aa) |
| | TMEM30A | Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...] (460 aa) |
| | SLC17A5 | SLC17A5 isoform 1. (453 aa) |
| | CR201_G0016196 | HLA-DQB1 isoform 5. (304 aa) |
| | HLA-DRB5 | Ig-like domain-containing protein. (266 aa) |
| | PRRT1 | Proline rich transmembrane protein 1. (306 aa) |
| | ATP6V1G2 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | HLA-A | Popy Class I histocompatibility antigen, A-1 alpha chain. (365 aa) |
| | SCGN | Secretagogin, EF-hand calcium binding protein. (276 aa) |
| | DTNBP1 | DTNBP1 isoform 1. (351 aa) |
| | CLTB | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa) |
| | GRIA1 | GRIA1 isoform 7. (888 aa) |
| | CD74 | CD74 isoform 2. (232 aa) |
| | SEC24A | SEC24 homolog A, COPII coat complex component. (1093 aa) |
| | SAR1B | Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa) |
| | SEPTIN8 | SEPT8 isoform 13; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (442 aa) |
| | PAM | Peptidylglycine alpha-amidating monooxygenase. (973 aa) |
| | MCTP1 | MCTP1 isoform 5. (774 aa) |
| | SCAMP1 | Secretory carrier-associated membrane protein. (338 aa) |
| | SV2C | SV2C isoform 2. (727 aa) |
| | RAB3C | RAB3C, member RAS oncogene family. (227 aa) |
| | PDCD6 | Programmed cell death protein 6 isoform X1. (191 aa) |
| | CPE | Carboxypeptidase E. (476 aa) |
| | SEC24D | SEC24D isoform 7. (1002 aa) |
| | SLC9B2 | Sodium/hydrogen exchanger 9B2; Na+/H+ antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane. Contributes to the regulation of intracellular pH, Na(+) content and organellar volume. Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells. Involved in sperm motility and fertility. It is controversial whether SLC9B2 plays a role in osteoclast differentiation or not (By similarity). (509 aa) |
| | SEC31A | Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1121 aa) |
| | USO1 | USO1 isoform 2. (969 aa) |
| | AREG | AREG isoform 1. (252 aa) |
| | WFS1 | WFS1 isoform 1. (964 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | SCAP | SCAP isoform 2. (1278 aa) |
| | BSN | BSN isoform 1. (3926 aa) |
| | SYNPR | SYNPR isoform 2. (265 aa) |
| | ITPR1 | ITPR1 isoform 3. (2769 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa) |
| | SYN2 | SYN2 isoform 1. (488 aa) |
| | AP1S3 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa) |
| | PTPRN | PTPRN isoform 1. (960 aa) |
| | ABCA12 | ABCA12 isoform 1. (2510 aa) |
| | TMEM163 | TMEM163 isoform 1. (290 aa) |
| | BIN1 | BIN1 isoform 9. (517 aa) |
| | SEMA4C | SEMA4C isoform 1; Belongs to the semaphorin family. (746 aa) |
| | OTOF | OTOF isoform 2. (1545 aa) |
| | SLC30A3 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (481 aa) |
| | CLHC1 | Clathrin heavy chain linker domain-containing protein 1. (585 aa) |
| | AFTPH | AFTPH isoform 3. (919 aa) |
| | RAB1A | RAB1A isoform 1. (205 aa) |
| | SPRED2 | Sprouty-related, EVH1 domain-containing protein 2; Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. (418 aa) |
| | TGFA | TGFA isoform 5. (159 aa) |
| | ATP6V1B1 | V-type proton ATPase subunit B, brain isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (509 aa) |
| | RAB11FIP5 | RAB11FIP5 isoform 2. (589 aa) |
| | SREBF2 | SREBF2 isoform 1. (1058 aa) |
| | SYNGR1 | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short- term and long-term synaptic plasticity (By similarity). Belongs to the synaptogyrin family. (654 aa) |
| | SYN3 | SYN3 isoform 1. (580 aa) |
| | AP1B1 | AP complex subunit beta. (946 aa) |
| | CLTCL1 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1640 aa) |
| | ATP6V1E1 | ATP6V1E1 isoform 1. (203 aa) |
| | DNAJC5 | DnaJ heat shock protein family (Hsp40) member C5. (198 aa) |
| | STX16 | STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa) |
| | SLC32A1 | SLC32A1 isoform 1. (527 aa) |
| | BCL2L1 | BCL2L1 isoform 2. (233 aa) |
| | SYNDIG1 | SYNDIG1 isoform 2. (254 aa) |
| | SEC23B | Protein transport protein Sec23B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. (767 aa) |
| | LAMP5 | Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain; Belongs to the LAMP family. (261 aa) |
| | SYT5 | SYT5 isoform 2. (386 aa) |
| | SYT3 | Synaptotagmin 3. (590 aa) |
| | CR201_G0029663 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (749 aa) |
| | SLC17A7 | SLC17A7 isoform 1. (539 aa) |
| | SYNGR4 | Synaptogyrin. (234 aa) |
| | CEACAM1 | CEACAM1 isoform 2. (527 aa) |
| | RAB3A | Ras-related protein Rab-3A. (203 aa) |
| | UNC13A | UNC13A isoform 4. (1518 aa) |
| | STX10 | STX10 isoform 6; Belongs to the syntaxin family. (249 aa) |
| | AP1M2 | AP1M2 isoform 1; Belongs to the adaptor complexes medium subunit family. (412 aa) |
| | RAB11B | RAB11B, member RAS oncogene family. (218 aa) |
| | PTPRS | PTPRS isoform 2. (1616 aa) |
| | CBARP | CBARP isoform 1. (313 aa) |
| | RAB27B | RAB27B, member RAS oncogene family. (218 aa) |
| | SYT4 | SYT4 isoform 1. (425 aa) |
| | DOC2B | DOC2B isoform 2. (301 aa) |
| | CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa) |
| | SYNGR2 | Synaptogyrin. (245 aa) |
| | CA4 | Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (312 aa) |
| | ATP6V0A1 | V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). (862 aa) |
| | GOSR2 | T0082108 isoform 1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa) |
| | SYNRG | SYNRG isoform 1. (1307 aa) |
| | SREBF1 | SREBF1 isoform 2. (1153 aa) |
| | VAMP2 | VAMP2 isoform 2. (116 aa) |
| | RPH3AL | RPH3AL isoform 1. (270 aa) |
| | ZNRF1 | Zinc and ring finger 1. (227 aa) |
| | AP1G1 | AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). (822 aa) |
| | SNTB2 | Beta-2-syntrophin. (537 aa) |
| | C16orf70 | Chromosome 16 open reading frame 70. (422 aa) |
| | ENSPPYP00000008251 | annotation not available (212 aa) |
| | PRRT2 | Proline-rich transmembrane protein 2; As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. (340 aa) |
| | DOC2A | Double C2-like domain-containing protein. (398 aa) |
| | ATP6V0C | V-type H+-transporting ATPase 16kDa proteolipid subunit. (128 aa) |
| | RAB26 | RAB26 isoform 1. (290 aa) |
| | SYNGR3 | Synaptogyrin. (196 aa) |
| | CR201_G0021500 | Synaptogyrin. (223 aa) |
| | MCTP2 | Multiple C2 and transmembrane domain containing 2. (878 aa) |
| | SV2B | Synaptic vesicle glycoprotein 2B. (683 aa) |
| | SCAMP5 | Secretory carrier-associated membrane protein 5; Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity). (240 aa) |
| | UNC13C | UNC13C isoform 1. (1180 aa) |
| | ENSPPYP00000007360 | annotation not available (418 aa) |
| | SCG3 | SCG3 isoform 1. (580 aa) |
| | AP1G2 | AP-1 complex subunit gamma. (785 aa) |
| | CLBA1 | Clathrin binding box of aftiphilin containing 1. (325 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | SEC23A | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (713 aa) |
| | RAB35 | RAB35, member RAS oncogene family. (201 aa) |
| | SVOP | Synaptic vesicle 2-related protein. (355 aa) |
| | SLC17A8 | Solute carrier family 17 member 8. (589 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1173 aa) |
| | SYT1 | Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] (377 aa) |
| | AQP2 | AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) |
| | SNAP47 | SNAP47 isoform 1. (459 aa) |
| | ENSPPYP00000000181 | annotation not available (121 aa) |
| | KLHL12 | KLHL12 isoform 2. (567 aa) |
| | SYT2 | SYT2 isoform 1. (359 aa) |
| | SEC16B | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (950 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | SV2A | Synaptic vesicle glycoprotein 2A; Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). (637 aa) |
| | SEC22B | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. (215 aa) |
| | SYT6 | SYT6 isoform 1. (509 aa) |
| | SLC6A17 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (729 aa) |
| | SYPL2 | Synaptophysin like 2. (272 aa) |
| | RAB3B | RAB3B, member RAS oncogene family. (219 aa) |
| | SLC6A9 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (652 aa) |
| | PEF1 | Penta-EF-hand domain containing 1. (284 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | TPRG1L | Tumor protein p63 regulated 1 like. (272 aa) |
| | GAD2 | GAD2 isoform 1. (545 aa) |
| | SEC24C | SEC24C isoform 1. (1095 aa) |
| | SAR1A | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). (198 aa) |
| | SEC31B | LOW QUALITY PROTEIN: protein transport protein Sec31B. (1149 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (217 aa) |
| | SLC18A2 | Solute carrier family 18 member A2. (514 aa) |
| | SEC23IP | SEC23IP isoform 1. (1018 aa) |
| | SYT8 | SYT8 isoform 4. (397 aa) |
| | SYT12 | SYT12 isoform 1. (421 aa) |
| | CNIH2 | Cornichon family AMPA receptor auxiliary protein 2. (160 aa) |
| | STX5 | STX5 isoform 1; Belongs to the syntaxin family. (355 aa) |
| | SYT7 | SYT7 isoform 1. (400 aa) |
| | RASSF10 | RASSF10 isoform 1. (419 aa) |
| | MAP6 | MAP6 isoform 1. (801 aa) |
| | SORL1 | SORL1 isoform 1. (2118 aa) |
| | NRGN | NRGN isoform 1. (140 aa) |
| | CR201_G0026159 | ABCC8 isoform 10. (685 aa) |
| | VAMP1 | Vesicle associated membrane protein 1. (118 aa) |
| | BORCS5 | BLOC-1 related complex subunit 5. (196 aa) |
| | DNM1L | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (686 aa) |
| | SYT10 | Synaptotagmin-10; Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis (By similarity). Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity); Belongs to the synaptotagmin family. (523 aa) |
| | SYT9 | SYT9 isoform 2. (173 aa) |
| | TMED10 | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] (216 aa) |
| | CPLX3 | CPLX3 isoform 1. (158 aa) |
| | DMXL2 | DMXL2 isoform 3. (2812 aa) |
| | TMED2 | Transmembrane p24 trafficking protein 2. (208 aa) |
