(7 nodes) Thiamine pyrophosphate binding network (Pongo abelii)

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Predicted Interactions

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Your Input:
	TKTL2	Transketolase like 2. (626 aa)
	ILVBL	ILVBL isoform 1; Belongs to the TPP enzyme family. (632 aa)
	DHTKD1	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (588 aa)
	OGDHL	2-oxoglutarate dehydrogenase-like, mitochondrial. (985 aa)
	TKTL1	TKTL1 isoform 1. (595 aa)
	OGDH	2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...] (1023 aa)
	HACL1	HACL1 isoform 2; Belongs to the TPP enzyme family. (578 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHTKD1	OGDH	ENSPPYP00000003298	ENSPPYP00000019712	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...]	0.583
DHTKD1	OGDHL	ENSPPYP00000003298	ENSPPYP00000002634	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	2-oxoglutarate dehydrogenase-like, mitochondrial.	0.561
HACL1	TKTL1	ENSPPYP00000015759	ENSPPYP00000023359	HACL1 isoform 2; Belongs to the TPP enzyme family.	TKTL1 isoform 1.	0.462
HACL1	TKTL2	ENSPPYP00000015759	ENSPPYP00000016949	HACL1 isoform 2; Belongs to the TPP enzyme family.	Transketolase like 2.	0.462
ILVBL	TKTL1	ENSPPYP00000010834	ENSPPYP00000023359	ILVBL isoform 1; Belongs to the TPP enzyme family.	TKTL1 isoform 1.	0.462
ILVBL	TKTL2	ENSPPYP00000010834	ENSPPYP00000016949	ILVBL isoform 1; Belongs to the TPP enzyme family.	Transketolase like 2.	0.462
OGDH	DHTKD1	ENSPPYP00000019712	ENSPPYP00000003298	2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase (E1) component of the 2- oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...]	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.583
OGDHL	DHTKD1	ENSPPYP00000002634	ENSPPYP00000003298	2-oxoglutarate dehydrogenase-like, mitochondrial.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.561
TKTL1	HACL1	ENSPPYP00000023359	ENSPPYP00000015759	TKTL1 isoform 1.	HACL1 isoform 2; Belongs to the TPP enzyme family.	0.462
TKTL1	ILVBL	ENSPPYP00000023359	ENSPPYP00000010834	TKTL1 isoform 1.	ILVBL isoform 1; Belongs to the TPP enzyme family.	0.462
TKTL1	TKTL2	ENSPPYP00000023359	ENSPPYP00000016949	TKTL1 isoform 1.	Transketolase like 2.	0.901
TKTL2	HACL1	ENSPPYP00000016949	ENSPPYP00000015759	Transketolase like 2.	HACL1 isoform 2; Belongs to the TPP enzyme family.	0.462
TKTL2	ILVBL	ENSPPYP00000016949	ENSPPYP00000010834	Transketolase like 2.	ILVBL isoform 1; Belongs to the TPP enzyme family.	0.462
TKTL2	TKTL1	ENSPPYP00000016949	ENSPPYP00000023359	Transketolase like 2.	TKTL1 isoform 1.	0.901