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| | RAB4A | RAB4A, member RAS oncogene family. (218 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa) |
| | MR1 | Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent (By similarity). (340 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | SNX27 | SNX27 isoform 2. (528 aa) |
| | SNX7 | SNX7 isoform 1. (473 aa) |
| | MCOLN3 | MCOLN3 isoform 4. (553 aa) |
| | WLS | Protein wntless homolog; Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity). (538 aa) |
| | ZFYVE9 | Zinc finger FYVE domain-containing protein. (1390 aa) |
| | EPS15 | Epidermal growth factor receptor pathway substrate 15. (896 aa) |
| | INPP5B | INPP5B isoform 1. (877 aa) |
| | STX12 | Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). (274 aa) |
| | EPHA8 | EPHA8 isoform 1. (734 aa) |
| | STAM | Signal transducing adaptor molecule. (540 aa) |
| | MARCHF8 | MARCH8 isoform 2. (291 aa) |
| | Washc2 | WASH complex subunit 2; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation- promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization and is involved in the fission of tubules that serve as transport intermediates during endosome sorting. Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC. Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex prob [...] (1331 aa) |
| | ENSPPYP00000002694 | annotation not available (159 aa) |
| | DKK1 | Dickkopf-like protein 1. (266 aa) |
| | PI4K2A | Phosphatidylinositol 4-kinase type 2 alpha. (479 aa) |
| | INPP5F | INPP5F isoform 1. (1037 aa) |
| | EHD1 | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary v [...] (534 aa) |
| | DAGLA | Diacylglycerol lipase alpha. (1043 aa) |
| | TSG101 | TSG101 isoform 4. (352 aa) |
| | TMEM9B | TMEM9 domain family member B. (198 aa) |
| | NEU3 | NEU3 isoform 2. (404 aa) |
| | MTMR2 | Myotubularin-related protein 2; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3- phosphate and phosphatidylinositol 3,5-bisphosphate (By similarity). Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5- phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Stabilizes SBF2/MTMR13 at the membranes. Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity). (640 aa) |
| | SORL1 | SORL1 isoform 1. (2118 aa) |
| | SNX19 | SNX19 isoform 1. (992 aa) |
| | RAB5B | Ras-related protein Rab-5B; Protein transport. Probably involved in vesicular traffic (By similarity). (285 aa) |
| | HSD17B6 | Hydroxysteroid 17-beta dehydrogenase 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | MON2 | MON2 isoform 1. (1716 aa) |
| | WASHC3 | WASHC3 isoform 2. (194 aa) |
| | WASHC4 | WASHC4 isoform 1. (1120 aa) |
| | APPL2 | APPL2 isoform 1. (564 aa) |
| | TPCN1 | TPCN1 isoform 2. (798 aa) |
| | SLC15A4 | SLC15A4 isoform 1. (577 aa) |
| | SNX6 | Sorting nexin-6, N-terminally processed; Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome- to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile call [...] (389 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] (463 aa) |
| | EHD4 | EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa) |
| | PLA2G4E | Phospholipase A2. (844 aa) |
| | SNX1 | Sorting nexin-1; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called en [...] (522 aa) |
| | PML | PML isoform 4. (869 aa) |
| | CR201_G0043368 | SH3GL3 isoform 2. (284 aa) |
| | VPS33B | VPS33B isoform 1; Belongs to the STXBP/unc-18/SEC1 family. (617 aa) |
| | ENSPPYP00000007763 | annotation not available (222 aa) |
| | KREMEN2 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (210 aa) |
| | ENSPPYP00000008037 | annotation not available (125 aa) |
| | CR201_G0034261 | GGA2 isoform 1. (451 aa) |
| | CLN3 | Battenin. (438 aa) |
| | SNX20 | SNX20 isoform 4. (289 aa) |
| | VAC14 | VAC14 component of PIKFYVE complex. (782 aa) |
| | CR201_G0054316 | LITAF isoform 8. (126 aa) |
| | CR201_G0041408 | WDR81 isoform 4. (691 aa) |
| | RABEP1 | Rabaptin, RAB GTPase binding effector protein 1. (862 aa) |
| | LLGL1 | LLGL1 isoform 2. (1051 aa) |
| | RAB5C | Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (216 aa) |
| | GGA3 | GGA3 isoform 1. (716 aa) |
| | SPHK1 | SPHK1 isoform 7. (470 aa) |
| | CR201_G0021153 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (616 aa) |
| | LDLRAD4 | Low density lipoprotein receptor class A domain containing 4. (306 aa) |
| | RAB31 | RAB31, member RAS oncogene family. (195 aa) |
| | PLPP2 | PLPP2 isoform 1. (270 aa) |
| | ABCA7 | ABCA7 isoform 3. (2147 aa) |
| | SH3GL1 | SH3GL1 isoform 4. (305 aa) |
| | UBXN6 | UBXN6 isoform 3. (436 aa) |
| | CLIP3 | CAP-Gly domain-containing linker protein 3; Functions as a cytoplasmic linker protein. Involved in TGN- endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes (By similarity). (547 aa) |
| | PLD3 | 5'-3' exonuclease PLD3; 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity). May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting (By similarity). (490 aa) |
| | ENSPPYP00000011649 | LOW QUALITY PROTEIN: killer cell immunoglobulin-like receptor 3DL2. (174 aa) |
| | LAMP5 | Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain; Belongs to the LAMP family. (261 aa) |
| | CR201_G0019710 | KIF16B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1102 aa) |
| | SNX5 | Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa) |
| | SYNDIG1 | SYNDIG1 isoform 2. (254 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (849 aa) |
| | SNX21 | SNX21 isoform 8. (158 aa) |
| | ATP9A | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1022 aa) |
| | PMEPA1 | Prostate transmembrane protein, androgen induced 1. (252 aa) |
| | DOP1B | DOP1 leucine zipper like protein B. (2298 aa) |
| | GGA1 | GGA1 isoform 1. (634 aa) |
| | INPP4A | INPP4A isoform 2. (971 aa) |
| | VAMP8 | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] (253 aa) |
| | RAB11FIP5 | RAB11FIP5 isoform 2. (589 aa) |
| | CD207 | CD207 isoform 1. (239 aa) |
| | ENSPPYP00000014104 | annotation not available (161 aa) |
| | WASHC1 | WAS protein family homolog 1. (467 aa) |
| | TMEM163 | TMEM163 isoform 1. (290 aa) |
| | STAM2 | STAM2 isoform 1. (563 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (959 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | PIKFYVE | PIKFYVE isoform 1. (2088 aa) |
| | ABCB6 | ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa) |
| | EPHA4 | EPHA4 isoform 2. (927 aa) |
| | BOK | BCL2 family apoptosis regulator BOK. (212 aa) |
| | RBSN | Rabenosyn, RAB effector. (784 aa) |
| | SNX4 | Sorting nexin-4; Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Belongs to the sorting nexin family. (450 aa) |
| | DTX3L | DTX3L isoform 1. (708 aa) |
| | APPL1 | APPL1 isoform 1. (708 aa) |
| | CMTM6 | CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...] (183 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | DNAJC13 | DNAJC13 isoform 1. (2243 aa) |
| | EPHB1 | EPHB1 isoform 1. (1057 aa) |
| | LAMP3 | Lysosomal associated membrane protein 3. (415 aa) |
| | ATP13A4 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1151 aa) |
| | ATP13A3 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1207 aa) |
| | ZFYVE28 | ZFYVE28 isoform 3. (959 aa) |
| | SORCS2 | SORCS2 isoform 3. (600 aa) |
| | NSG1 | Neuronal vesicle trafficking-associated protein 1; Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatoden [...] (185 aa) |
| | PI4K2B | PI4K2B isoform 1. (481 aa) |
| | TMEM165 | GDT1 family protein. (324 aa) |
| | MARCHF1 | MARCH1 isoform 2. (542 aa) |
| | CLCN3 | H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity). (866 aa) |
| | ZFYVE16 | Zinc finger FYVE domain-containing protein. (1539 aa) |
| | MARCHF3 | Membrane associated ring-CH-type finger 3. (253 aa) |
| | PDLIM4 | PDZ and LIM domain 4. (330 aa) |
| | GRIA1 | GRIA1 isoform 7. (888 aa) |
| | NSG2 | Neuronal vesicle trafficking associated 2. (171 aa) |
| | RUFY1 | RUFY1 isoform 1. (725 aa) |
| | KIAA0319 | KIAA0319 isoform 5. (1072 aa) |
| | Poab-F | MHC class I protein; Belongs to the MHC class I family. (346 aa) |
| | HLA-A | Popy Class I histocompatibility antigen, A-1 alpha chain. (365 aa) |
| | FGD2 | FGD2 isoform 2. (655 aa) |
| | SNX3 | Sorting nexin-3; Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo- selective subcomplex (CSC). May act in part as component of the SNX3- retromer complex which mediates the retrograde [...] (162 aa) |
| | FIG4 | FIG4 isoform 1. (891 aa) |
| | CLVS2 | CLVS2 isoform 1. (327 aa) |
| | STX7 | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). (261 aa) |
| | CR201_G0055889 | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | MHC-Poab-B | MHC class I antigen; Belongs to the MHC class I family. (323 aa) |
| | CR201_G0042422 | HLA-G isoform 2; Belongs to the MHC class I family. (365 aa) |
| | LOC100460187 | MHC class II protein; Belongs to the MHC class II family. (254 aa) |
| | CR201_G0055693 | HLA-B isoform 1; Belongs to the MHC class I family. (362 aa) |
| | CR201_G0042422-3 | HLA-G isoform 6. (259 aa) |
| | ENSPPYP00000019353 | HLA class I histocompatibility antigen, alpha chain G isoform X1. (66 aa) |
| | TMEM184A | TMEM184A isoform 1. (203 aa) |
| | SNX8 | Sorting nexin 8. (465 aa) |
| | RABGEF1 | RABGEF1 isoform 2. (544 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | GPNMB | Glycoprotein nmb. (560 aa) |
| | SNX13 | SNX13 isoform 2. (919 aa) |
| | STEAP4 | STEAP4 metalloreductase. (459 aa) |
| | NAPEPLD | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of these bioactive fatty acid ethanolamides (FAEs), including anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid and vanilloid receptors (By similarity). As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis [...] (393 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa) |
| | WDR91 | WD repeat-containing protein 91; Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3- phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis. (747 aa) |
| | SLC39A14 | Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron. (507 aa) |
| | CLVS1 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). (354 aa) |
| | SNX16 | Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling (By similarity); Belongs to the sorting nexin family. (344 aa) |
| | PLEKHF2 | Pleckstrin homology and FYVE domain containing 2. (249 aa) |
| | ARC | Activity regulated cytoskeleton associated protein. (396 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | SNX30 | Sorting nexin family member 30. (437 aa) |
| | RAB14 | Ras-related protein Rab-14; Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell [...] (179 aa) |
| | LOC100431914 | FCGR1A isoform 2. (373 aa) |
| | ENSPPYP00000022414 | annotation not available (913 aa) |
| | CLCN4 | Chloride channel protein. (760 aa) |
| | CR201_G0052920 | GRIPAP1 isoform 14. (643 aa) |
| | SNX12 | Sorting nexin 12. (162 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | OCRL | OCRL isoform 3. (855 aa) |
| | MMGT1 | Membrane magnesium transporter 1; Mediates Mg(2+) transport. (131 aa) |
| | SLC9A6 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa) |
| | ATP11C | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1129 aa) |
| | RCC2 | RCC2 isoform 1. (522 aa) |
| | MTMR4 | Myotubularin related protein 4. (1227 aa) |
| | ATP11B | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (599 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1000 aa) |
| | SNX2 | Sorting nexin-2; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called en [...] (523 aa) |
