STRINGSTRING
NSG1 NSG1 TMEM165 TMEM165 ARFIP1 ARFIP1 MARCHF1 MARCHF1 SCAMP1 SCAMP1 COG7 COG7 BAIAP3 BAIAP3 SCAMP5 SCAMP5 RHOBTB3 RHOBTB3 CD74 CD74 NDST1 NDST1 NSG2 NSG2 KIF13A KIF13A HLA-DRB5 HLA-DRB5 CR201_G0016196 CR201_G0016196 FUT9 FUT9 CLVS2 CLVS2 IGF2R IGF2R CR201_G0016191 CR201_G0016191 ENSPPYP00000019293 ENSPPYP00000019293 HLA-DQB2 HLA-DQB2 CR201_G0016218 CR201_G0016218 CR201_G0016219 CR201_G0016219 LOC100460187 LOC100460187 ENSPPYP00000019322 ENSPPYP00000019322 VPS52 VPS52 CR201_G0016218-2 CR201_G0016218-2 AP4M1 AP4M1 AP1S1 AP1S1 CALN1 CALN1 COG5 COG5 SCAMP2 SCAMP2 AP4E1 AP4E1 SLC24A5 SLC24A5 CLBA1 CLBA1 PLD4 PLD4 IMPAD1 IMPAD1 VPS13B VPS13B AP4S1 AP4S1 ATP7B ATP7B COG3 COG3 COG6 COG6 ARL1 ARL1 LGR5 LGR5 ENSPPYP00000004926 ENSPPYP00000004926 M6PR M6PR CR201_G0036182 CR201_G0036182 ARFIP2 ARFIP2 VPS51 VPS51 VTI1A VTI1A HTR7 HTR7 USP6NL USP6NL VAMP3 VAMP3 AP4B1 AP4B1 GOLPH3L GOLPH3L SCAMP3 SCAMP3 CLTC CLTC TMEM79 TMEM79 RAB31 RAB31 AP1M2 AP1M2 STX10 STX10 CLIP3 CLIP3 MMP24 MMP24 LGR6 LGR6 STX6 STX6 VAMP4 VAMP4 COG2 COG2 ATP9A ATP9A STX16 STX16 GNAS GNAS AP1B1 AP1B1 CABP7 CABP7 ST3GAL1 ST3GAL1 CLTA CLTA RGP1 RGP1 MLANA MLANA RIC1 RIC1 RABEPK RABEPK AP1S2 AP1S2 ATP7A ATP7A HLA-DPB1 HLA-DPB1 GCC2 GCC2 AFTPH AFTPH TEPSIN TEPSIN COG1 COG1 LLGL1 LLGL1 ENSPPYP00000008720 ENSPPYP00000008720 ATP2C2 ATP2C2 VPS54 VPS54 SLC30A6 SLC30A6 TGOLN2 TGOLN2 AP1S3 AP1S3 BOK BOK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NSG1Neuronal vesicle trafficking-associated protein 1; Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatoden [...] (185 aa)
TMEM165GDT1 family protein. (324 aa)
ARFIP1ARFIP1 isoform 2. (373 aa)
MARCHF1MARCH1 isoform 2. (542 aa)
SCAMP1Secretory carrier-associated membrane protein. (338 aa)
COG7COG7 isoform 1. (771 aa)
BAIAP3BAIAP3 isoform 3. (1072 aa)
SCAMP5Secretory carrier-associated membrane protein 5; Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity). (240 aa)
RHOBTB3RHOBTB3 isoform 7. (548 aa)
CD74CD74 isoform 2. (232 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
NSG2Neuronal vesicle trafficking associated 2. (171 aa)
KIF13AKIF13A isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1788 aa)
HLA-DRB5Ig-like domain-containing protein. (266 aa)
CR201_G0016196HLA-DQB1 isoform 5. (304 aa)
FUT9Fucosyltransferase 9. (359 aa)
CLVS2CLVS2 isoform 1. (327 aa)
IGF2RIGF2R isoform 1. (2446 aa)
CR201_G0016191HLA-DRB5 isoform 1. (290 aa)
ENSPPYP00000019293HLA class II histocompatibility antigen, DRB1-11 beta chain isoform X1. (266 aa)
HLA-DQB2Major histocompatibility complex, class II, DQ beta 2. (264 aa)
CR201_G0016218HLA-DPA1 isoform 1; Belongs to the MHC class II family. (260 aa)
CR201_G0016219HLA-DPB1 isoform 1. (283 aa)
LOC100460187MHC class II protein; Belongs to the MHC class II family. (254 aa)
ENSPPYP00000019322annotation not available (157 aa)
VPS52VPS52 isoform 4. (723 aa)
CR201_G0016218-2HLA-DPA1 isoform 3. (239 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (245 aa)
CALN1CALN1 isoform 1. (219 aa)
COG5COG5 isoform 5. (859 aa)
SCAMP2Secretory carrier-associated membrane protein. (329 aa)
AP4E1AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1137 aa)
SLC24A5SLC24A5 isoform 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (498 aa)
CLBA1Clathrin binding box of aftiphilin containing 1. (325 aa)
PLD4PLD4 isoform 1. (506 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
VPS13BVPS13B isoform 3. (3944 aa)
AP4S1Adaptor related protein complex 4 subunit sigma 1. (159 aa)
ATP7BATP7B isoform 3. (1434 aa)
COG3COG3 isoform 1. (742 aa)
COG6Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (657 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
LGR5LGR5 isoform 1. (907 aa)
ENSPPYP00000004926annotation not available (398 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (278 aa)
CR201_G0036182CRACR2A isoform 1. (319 aa)
ARFIP2ARFIP2 isoform 2. (342 aa)
VPS51VPS51 isoform 3. (303 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (217 aa)
HTR7HTR7 isoform 3; Belongs to the G-protein coupled receptor 1 family. (459 aa)
USP6NLUSP6 N-terminal like. (827 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
AP4B1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
GOLPH3LGolgi phosphoprotein 3 like. (285 aa)
SCAMP3Secretory carrier-associated membrane protein. (347 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
TMEM79TMEM79 isoform 2. (394 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
AP1M2AP1M2 isoform 1; Belongs to the adaptor complexes medium subunit family. (412 aa)
STX10STX10 isoform 6; Belongs to the syntaxin family. (249 aa)
CLIP3CAP-Gly domain-containing linker protein 3; Functions as a cytoplasmic linker protein. Involved in TGN- endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes (By similarity). (547 aa)
MMP24MMP24 isoform 1. (514 aa)
LGR6LGR6 isoform 2. (892 aa)
STX6Syntaxin-6; Involved in intracellular vesicle trafficking. (255 aa)
VAMP4VAMP4 isoform 1. (134 aa)
COG2COG2 isoform 1. (738 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1022 aa)
STX16STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa)
GNASGNAS isoform 2. (1037 aa)
AP1B1AP complex subunit beta. (946 aa)
CABP7Calcium binding protein 7. (215 aa)
ST3GAL1ST3GAL1 isoform 1; Belongs to the glycosyltransferase 29 family. (340 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
MLANAMLANA isoform 1. (118 aa)
RIC1RIC1 isoform 3. (1344 aa)
RABEPKRABEPK isoform 2. (363 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
GCC2GCC2 isoform 3. (1686 aa)
AFTPHAFTPH isoform 3. (919 aa)
TEPSINTEPSIN isoform 1. (492 aa)
COG1COG1 isoform 2. (980 aa)
LLGL1LLGL1 isoform 2. (1051 aa)
ENSPPYP00000008720annotation not available (160 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (946 aa)
VPS54VPS54 subunit of GARP complex. (977 aa)
SLC30A6SLC30A6 isoform 7. (412 aa)
TGOLN2TGOLN2 isoform 3. (369 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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