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| | SLC11A2 | SLC11A2 isoform 12. (573 aa) |
| | SLC8A1 | SLC8A1 isoform 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | HDAC6 | HDAC6 isoform 2. (1208 aa) |
| | MPV17 | Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2; Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity); Belongs to the nuclear hormone receptor family. (598 aa) |
| | PLA2R1 | Soluble secretory phospholipase A2 receptor; Receptor for secretory phospholipase A2 (sPLA2). Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marro [...] (1463 aa) |
| | ENSPPYP00000022416 | annotation not available (110 aa) |
| | CR201_G0031565 | ALDH3B1 isoform 7. (196 aa) |
| | ABL1 | Tyrosine-protein kinase. (948 aa) |
| | SETX | SETX isoform 1. (2678 aa) |
| | CR201_G0027499 | ABL1 isoform 3. (48 aa) |
| | ENDOG | Endonuclease. (297 aa) |
| | ERCC6L2 | ERCC6L2 isoform 5. (1489 aa) |
| | FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa) |
| | DAPK1 | DAPK1 isoform 2. (1430 aa) |
| | ENSPPYP00000021637 | annotation not available (151 aa) |
| | CR201_G0001564 | FXN isoform 5. (137 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | ERMP1 | ERMP1 isoform 1. (979 aa) |
| | CR201_G0001895 | CDKN2A isoform 2. (173 aa) |
| | NUDT2 | Nudix hydrolase 2. (147 aa) |
| | SIGMAR1 | Sigma non-opioid intracellular receptor 1. (223 aa) |
| | MELK | Non-specific serine/threonine protein kinase. (651 aa) |
| | HSF1 | HSF1 isoform 2. (594 aa) |
| | OXR1 | Oxidation resistance 1. (874 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | STAU2 | STAU2 isoform 7. (607 aa) |
| | TRPA1 | TRPA1 isoform 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa) |
| | PENK | PENK isoform 3. (267 aa) |
| | ENSPPYP00000020851 | annotation not available (155 aa) |
| | BRF2 | BRF2 isoform 1. (418 aa) |
| | GSR | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (472 aa) |
| | MSRA | MSRA isoform 1. (236 aa) |
| | AGAP3 | AGAP3 isoform 6. (825 aa) |
| | NOS3 | NOS3 isoform 2. (833 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | CD36 | CD36 isoform 15; Belongs to the CD36 family. (472 aa) |
| | IL6 | IL6 isoform 2. (212 aa) |
| | AQP1 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (323 aa) |
| | NME8 | NME8 isoform 1. (588 aa) |
| | CR201_G0040641 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (143 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (306 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | CHCHD2 | CHCHD2 isoform 1. (151 aa) |
| | VKORC1L1 | VKORC1L1 isoform 1. (116 aa) |
| | NCF1 | NCF1 isoform 3. (364 aa) |
| | SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (158 aa) |
| | TNFAIP3 | TNFAIP3 isoform 1. (790 aa) |
| | MAP3K5 | MAP3K5 isoform 1. (1327 aa) |
| | ARG1 | Arginase. (322 aa) |
| | PTPRK | PTPRK isoform 7. (1485 aa) |
| | RWDD1 | RWDD1 isoform 1. (235 aa) |
| | HDAC2 | Histone deacetylase 2. (580 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | ENSPPYP00000018755 | annotation not available (57 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | GPX5 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa) |
| | EDN1 | EDN1 isoform 1. (212 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | PPARGC1B | PPARGC1B isoform 1. (1022 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa) |
| | GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa) |
| | PRKAA1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] (559 aa) |
| | EDNRA | EDNRA isoform 1; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | SLC7A11 | Cystine/glutamate transporter; Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. (472 aa) |
| | PKD2 | PKD2 isoform 1. (968 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (384 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | CPEB2 | CPEB2 isoform 5. (598 aa) |
| | ETV5 | ETV5 isoform 1. (510 aa) |
| | ECT2 | ECT2 isoform 4. (913 aa) |
| | TREX1 | Three prime repair exonuclease 1. (369 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | ARL6IP5 | PRA1 family protein 3; Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity- dependent manner. May be involved in membrane traffic. (188 aa) |
| | FANCD2 | FANCD2 isoform 1. (1404 aa) |
| | ENSPPYP00000014969 | annotation not available (54 aa) |
| | ANKZF1 | ANKZF1 isoform 15. (776 aa) |
| | ENSPPYP00000014644 | annotation not available (149 aa) |
| | ENSPPYP00000014504 | annotation not available (54 aa) |
| | PJVK | DFNB59 isoform 1. (352 aa) |
| | PRKRA | PRKRA isoform 1. (312 aa) |
| | NFE2L2 | NFE2L2 isoform 2. (606 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | PDK1 | Protein-serine/threonine kinase. (463 aa) |
| | ADNP2 | ADNP2 isoform 2. (1125 aa) |
| | BCL2 | BCL2 isoform 1. (238 aa) |
| | IMPACT | Impact RWD domain protein. (320 aa) |
| | CR201_G0012267 | Protein-serine/threonine kinase. (406 aa) |
| | NFE2L1 | Endoplasmic reticulum membrane sensor NFE2L1; [Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane sensor that translocates into the nucleus in response to various stresses to act as a transcription factor (By similarity). Constitutes a precursor of the transcription factor NRF1 (By similarity). Able to detect various cellular stresses, such as cholesterol excess, oxidative stress or proteasome inhibition (By similarity). In response to stress, it is released from the endoplasmic reticulum membrane following cleavage by the protease DDI2 and translocates into [...] (788 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase 1, mitochondrial; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. Belongs to the pyrroline-5-carboxylate reductase family. (319 aa) |
| | SPHK1 | SPHK1 isoform 7. (470 aa) |
| | ERN1 | ERN1 isoform 1. (963 aa) |
| | PCGF2 | PCGF2 isoform 1. (347 aa) |
| | MPO | Myeloperoxidase. (745 aa) |
| | RNF112 | RNF112 isoform 1. (632 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | NQO1 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. (274 aa) |
| | SMPD3 | SMPD3 isoform 1. (629 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa) |
| | MMP2 | MMP2 isoform 3. (559 aa) |
| | STX4 | STX4 isoform 4; Belongs to the syntaxin family. (296 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) |
| | ABCC1 | ABCC1 isoform 3. (1199 aa) |
| | SELENOS | SELENOS isoform 1. (188 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | PML | PML isoform 4. (869 aa) |
| | TPM1 | TPM1 isoform 2; Belongs to the tropomyosin family. (326 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa) |
| | GSKIP | GSK3B interacting protein. (139 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | LOC100446892 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction catalyzed [...] (315 aa) |
| | CR201_G0009767 | HIF1A isoform 5. (735 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (912 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | DHRS2 | DHRS2 isoform 3. (280 aa) |
| | STK24 | STK24 isoform 5. (358 aa) |
| | FOXO1 | FOXO1 isoform 1. (654 aa) |
| | STX2 | STX2 isoform 2; Belongs to the syntaxin family. (263 aa) |
| | CAMKK2 | Calcium/calmodulin dependent protein kinase kinase 2. (588 aa) |
| | CR201_G0000922 | PXN isoform 2; Belongs to the paxillin family. (381 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (950 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | PYROXD1 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response (By similarity). Required for normal sarcomere structure and muscle fiber integrity (By similarity). (444 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1. (155 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (418 aa) |
| | RPS3 | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8- dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] (243 aa) |
| | IL18BP | Interleukin 18 binding protein. (194 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] (583 aa) |
| | PRR5L | Proline rich 5 like. (368 aa) |
| | PRDX5 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (344 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | CCS | Copper chaperone for superoxide dismutase. (274 aa) |
| | ALDH3B1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (447 aa) |
| | ENSPPYP00000003305 | annotation not available (159 aa) |
| | BNIP3 | BNIP3 isoform 1. (256 aa) |
| | MGMT | MGMT isoform 1. (238 aa) |
| | PAX2 | PAX2 isoform 3. (388 aa) |
| | CHUK | CHUK isoform 1. (746 aa) |
| | ANKRD2 | ANKRD2 isoform 1. (360 aa) |
| | SIRT1 | SIRT1 isoform 1. (746 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (209 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | NET1 | NET1 isoform 1. (596 aa) |
| | AKR1C4 | Aldo-keto reductase family 1 member C3 homolog; Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. (323 aa) |
| | PARK7 | PARK7 isoform 1. (189 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | SELENON | T0151383 isoform 1. (556 aa) |
| | SESN2 | Sestrin-2; Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. This stress-inducible metabolic regulator also plays a role in protection against oxidative and genotoxic stresses. May negatively regulate protein translation in response to endoplasmic reticulum stress, via TORC1. May positively regulate the transcripti [...] (480 aa) |
| | ADPRHL2 | ADP-ribosylhydrolase like 2. (364 aa) |
| | ZC3H12A | ZC3H12A isoform 1. (599 aa) |
| | PRDX1 | PRDX1 isoform 2. (199 aa) |
| | GPX7 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (187 aa) |
| | PRKAA2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] (552 aa) |
| | JUN | JUN isoform 1; Belongs to the bZIP family. (334 aa) |
| | SLC25A24 | SLC25A24 isoform 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (421 aa) |
| | ARNT | ARNT isoform 1. (789 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase 2; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity). Involved in cellular response to oxidative stress (By similarity); Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (972 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa) |
| | APOA4 | Apolipoprotein A4. (416 aa) |
| | PLEKHA1 | PLEKHA1 isoform 4. (383 aa) |
| | ZNF622 | ZNF622 isoform 1. (378 aa) |
| | PRDX2 | Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2); Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (198 aa) |
| | PDCD10 | PDCD10 isoform 1. (186 aa) |
| | STK25 | Serine/threonine kinase 25. (435 aa) |
| | ZNF277 | Zinc finger protein 277. (517 aa) |
| | LRRK2 | LRRK2 isoform 3. (1560 aa) |
| | SIRT2 | NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Functions in the antephase checkpoint preventing precocious mitotic entry in response to microtu [...] (389 aa) |
| | KDM6B | KDM6B isoform 2. (942 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (158 aa) |
| | EZH2 | EZH2 isoform 5. (704 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (543 aa) |
| | AIFM1 | AIFM1 isoform 7. (611 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | NOX1 | NOX1 isoform 2. (522 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | LONP1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (745 aa) |
| | KEAP1 | Kelch-like ECH-associated protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine [...] (624 aa) |
| | KLF2 | KLF2 isoform 1. (356 aa) |
| | TMEM161A | TMEM161A isoform 9. (257 aa) |
| | ENSPPYP00000010984 | annotation not available (156 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | SLC4A11 | Solute carrier family 4 member 11. (918 aa) |
| | SIRPA | SIRPA isoform 2. (503 aa) |
| | SRXN1 | Sulfiredoxin-1. (166 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) |
| | TP53INP2 | TP53INP2 isoform 1. (212 aa) |
| | ROMO1 | ROMO1 isoform 1. (211 aa) |
| | SRC | Tyrosine-protein kinase. (553 aa) |
| | CHD6 | Chromodomain helicase DNA binding protein 6. (2717 aa) |
| | OSER1 | Oxidative stress-responsive serine-rich protein 1. (292 aa) |
| | MMP9 | MMP9 isoform 1. (707 aa) |
| | STAU1 | STAU1 isoform 2. (576 aa) |
| | RBM11 | RBM11 isoform 5. (281 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (130 aa) |
| | TRPM2 | TRPM2 isoform 3. (1302 aa) |
| | XBP1 | X-box binding protein 1. (262 aa) |
| | MGAT3 | MGAT3 isoform 1. (533 aa) |
| | ATF4 | ATF4 isoform 1. (352 aa) |
| | ENSPPYP00000013398 | annotation not available (195 aa) |
| | PRODH | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (509 aa) |
| | FABP1 | Fatty acid binding protein 1. (127 aa) |
| | HTRA2 | HtrA serine peptidase 2. (458 aa) |
| | VRK2 | VRK2 isoform 3. (494 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial; RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (By simi [...] (785 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (869 aa) |
