31 items (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VEGFD	VEGFD isoform 1; Belongs to the PDGF/VEGF growth factor family. (354 aa)
	CCL5	C-C motif chemokine. (91 aa)
	GALK2	N-acetylgalactosamine kinase; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations (By similarity). (543 aa)
	ALKBH1	AlkB homolog 1, histone H2A dioxygenase. (389 aa)
	PGF	PGF isoform 1; Belongs to the PDGF/VEGF growth factor family. (161 aa)
	LGALS3	Galectin. (309 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa)
	HPS5	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1129 aa)
	VEGFB	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
	S100A15A	Protein S100-A15A; Belongs to the S-100 family. (108 aa)
	CX3CL1	CX3CL1 isoform 1. (397 aa)
	CCL16	C-C motif chemokine. (120 aa)
	CCL15	C-C motif chemokine. (113 aa)
	MIF	Macrophage migration inhibitory factor. (115 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	SCG2	Secretogranin-2; Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules. (617 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (473 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)
	VEGFC	VEGFC isoform 1; Belongs to the PDGF/VEGF growth factor family. (418 aa)
	GDNF	GDNF isoform 6. (185 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	GPNMB	Glycoprotein nmb. (560 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
	LOC112131751	Beta-defensin 109. (87 aa)
	LOC100434671	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (72 aa)
	LOC100435661	DEFB103B isoform 1. (67 aa)
	LOC100436028	DEFB4A isoform 1. (64 aa)
	LOC112134719	Beta-defensin 130-like. (79 aa)
	COLEC10	Collectin subfamily member 10. (277 aa)
	LOC100445600	DEFB130A isoform 1. (79 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGF10	ENSPPYP00000006620	ENSPPYP00000017257	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.682
BMP4	GDNF	ENSPPYP00000006620	ENSPPYP00000017215	Bone morphogenetic protein 4.	GDNF isoform 6.	0.546
BMP4	WNT5A	ENSPPYP00000006620	ENSPPYP00000015420	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.488
CCL15	CCL5	ENSPPYP00000009218	ENSPPYP00000009214	C-C motif chemokine.	C-C motif chemokine.	0.942
CCL15	CXCL10	ENSPPYP00000009218	ENSPPYP00000016587	C-C motif chemokine.	C-X-C motif chemokine.	0.418
CCL16	CCL5	ENSPPYP00000009217	ENSPPYP00000009214	C-C motif chemokine.	C-C motif chemokine.	0.992
CCL16	CX3CL1	ENSPPYP00000009217	ENSPPYP00000008345	C-C motif chemokine.	CX3CL1 isoform 1.	0.422
CCL16	CXCL10	ENSPPYP00000009217	ENSPPYP00000016587	C-C motif chemokine.	C-X-C motif chemokine.	0.594
CCL5	CCL15	ENSPPYP00000009214	ENSPPYP00000009218	C-C motif chemokine.	C-C motif chemokine.	0.942
CCL5	CCL16	ENSPPYP00000009214	ENSPPYP00000009217	C-C motif chemokine.	C-C motif chemokine.	0.992
CCL5	CX3CL1	ENSPPYP00000009214	ENSPPYP00000008345	C-C motif chemokine.	CX3CL1 isoform 1.	0.803
CCL5	CXCL10	ENSPPYP00000009214	ENSPPYP00000016587	C-C motif chemokine.	C-X-C motif chemokine.	0.998
CCL5	HGF	ENSPPYP00000009214	ENSPPYP00000020015	C-C motif chemokine.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.428
CCL5	LGALS3	ENSPPYP00000009214	ENSPPYP00000006633	C-C motif chemokine.	Galectin.	0.562
CCL5	MIF	ENSPPYP00000009214	ENSPPYP00000012981	C-C motif chemokine.	Macrophage migration inhibitory factor.	0.563
CX3CL1	CCL16	ENSPPYP00000008345	ENSPPYP00000009217	CX3CL1 isoform 1.	C-C motif chemokine.	0.422
CX3CL1	CCL5	ENSPPYP00000008345	ENSPPYP00000009214	CX3CL1 isoform 1.	C-C motif chemokine.	0.803
CX3CL1	CXCL10	ENSPPYP00000008345	ENSPPYP00000016587	CX3CL1 isoform 1.	C-X-C motif chemokine.	0.789
CXCL10	CCL15	ENSPPYP00000016587	ENSPPYP00000009218	C-X-C motif chemokine.	C-C motif chemokine.	0.418
CXCL10	CCL16	ENSPPYP00000016587	ENSPPYP00000009217	C-X-C motif chemokine.	C-C motif chemokine.	0.594