23 items (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HBQ1	HBQ1 isoform 1; Belongs to the globin family. (139 aa)
	MPO	Myeloperoxidase. (745 aa)
	LPO	LPO isoform 1. (712 aa)
	EPX	EPX isoform 1. (516 aa)
	PXDN	PXDN isoform 2. (1557 aa)
	TPO	TPO isoform 7. (884 aa)
	GPX3	GPX3 isoform 10. (153 aa)
	PXDNL	PXDNL isoform 2. (883 aa)
	GPX1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	APOA4	Apolipoprotein A4. (416 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa)
	PRDX1	PRDX1 isoform 2. (199 aa)
	PRDX5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (344 aa)
	HBE1	Hemoglobin subunit epsilon 1; Belongs to the globin family. (147 aa)
	ENSPPYP00000004103	annotation not available (98 aa)
	ENSPPYP00000004104	annotation not available (137 aa)
	LOC100438895	HBG2 isoform 1; Belongs to the globin family. (147 aa)
	LOC100439631	HBG1 isoform 1; Belongs to the globin family. (147 aa)
	HBB	Hemoglobin subunit beta; Belongs to the globin family. (147 aa)
	DUOX2	DUOX2 isoform 1. (1545 aa)
	DUOX1	DUOX1 isoform 1. (1544 aa)
	HBM	Hemoglobin subunit mu; Belongs to the globin family. (141 aa)
	LOC112128473	HBA1 isoform 1; Belongs to the globin family. (142 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAT	GPX1	ENSPPYP00000024526	ENSPPYP00000023524	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.459
CAT	GPX3	ENSPPYP00000024526	ENSPPYP00000017858	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	GPX3 isoform 10.	0.459
CAT	PRDX1	ENSPPYP00000024526	ENSPPYP00000001637	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	PRDX1 isoform 2.	0.648
CAT	PRDX5	ENSPPYP00000024526	ENSPPYP00000003590	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.464
DUOX1	DUOX2	ENSPPYP00000007298	ENSPPYP00000007295	DUOX1 isoform 1.	DUOX2 isoform 1.	0.943
DUOX1	GPX3	ENSPPYP00000007298	ENSPPYP00000017858	DUOX1 isoform 1.	GPX3 isoform 10.	0.436
DUOX2	DUOX1	ENSPPYP00000007295	ENSPPYP00000007298	DUOX2 isoform 1.	DUOX1 isoform 1.	0.943
GPX1	CAT	ENSPPYP00000023524	ENSPPYP00000024526	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.459
GPX1	GPX3	ENSPPYP00000023524	ENSPPYP00000017858	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	GPX3 isoform 10.	0.907
GPX3	CAT	ENSPPYP00000017858	ENSPPYP00000024526	GPX3 isoform 10.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family.	0.459
GPX3	DUOX1	ENSPPYP00000017858	ENSPPYP00000007298	GPX3 isoform 10.	DUOX1 isoform 1.	0.436
GPX3	GPX1	ENSPPYP00000017858	ENSPPYP00000023524	GPX3 isoform 10.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.907
GPX3	MPO	ENSPPYP00000017858	ENSPPYP00000009253	GPX3 isoform 10.	Myeloperoxidase.	0.505
GPX3	PRDX1	ENSPPYP00000017858	ENSPPYP00000001637	GPX3 isoform 10.	PRDX1 isoform 2.	0.617
GPX3	PRDX5	ENSPPYP00000017858	ENSPPYP00000003590	GPX3 isoform 10.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.410
GPX3	PXDN	ENSPPYP00000017858	ENSPPYP00000014163	GPX3 isoform 10.	PXDN isoform 2.	0.517
HBB	HBE1	ENSPPYP00000004109	ENSPPYP00000004102	Hemoglobin subunit beta; Belongs to the globin family.	Hemoglobin subunit epsilon 1; Belongs to the globin family.	0.486
HBB	HBM	ENSPPYP00000004109	ENSPPYP00000007810	Hemoglobin subunit beta; Belongs to the globin family.	Hemoglobin subunit mu; Belongs to the globin family.	0.959
HBB	HBQ1	ENSPPYP00000004109	ENSPPYP00000007812	Hemoglobin subunit beta; Belongs to the globin family.	HBQ1 isoform 1; Belongs to the globin family.	0.957
HBB	LOC100438895	ENSPPYP00000004109	ENSPPYP00000004105	Hemoglobin subunit beta; Belongs to the globin family.	HBG2 isoform 1; Belongs to the globin family.	0.539