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| | TNR | TNR isoform 1. (1309 aa) |
| | RGS7 | RGS7 isoform 3. (469 aa) |
| | CAPN2 | CAPN2 isoform 2; Belongs to the peptidase C2 family. (655 aa) |
| | CD55 | CD55 isoform 4. (381 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1110 aa) |
| | PTPRC | PTPRC isoform 2. (1267 aa) |
| | PTGS2 | PTGS2 isoform 1. (604 aa) |
| | NPHS2 | NPHS2 stomatin family member, podocin. (383 aa) |
| | FASLG | FASLG isoform 1; Belongs to the tumor necrosis factor family. (280 aa) |
| | SELE | SELE isoform 3. (601 aa) |
| | CR201_G0042066 | C1orf226 isoform 2. (695 aa) |
| | ITLN1 | LOW QUALITY PROTEIN: intelectin-1. (311 aa) |
| | CD48 | CD48 isoform 1. (259 aa) |
| | ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1000 aa) |
| | CD1A | CD1A isoform 1. (331 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) |
| | CHRNB2 | CHRNB2 isoform 2. (518 aa) |
| | CD2 | CD2 isoform 1. (351 aa) |
| | ATP1A1 | ATP1A1 isoform 7. (1003 aa) |
| | LAMTOR5 | LAMTOR5 isoform 1. (182 aa) |
| | S1PR1 | S1PR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | BCL10 | BCL10 isoform 1. (263 aa) |
| | FYB2 | FYN binding protein 2. (729 aa) |
| | PLPP3 | T0071805 isoform 3. (313 aa) |
| | LRP8 | LRP8 isoform 1. (955 aa) |
| | SLC2A1 | SLC2A1 isoform 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa) |
| | PPT1 | Palmitoyl-protein thioesterase 1. (306 aa) |
| | LCK | Tyrosine-protein kinase. (487 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | STX12 | Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). (274 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | PDPN | PDPN isoform 1. (236 aa) |
| | TNFRSF1B | TNFRSF1B isoform 2. (455 aa) |
| | PARK7 | PARK7 isoform 1. (189 aa) |
| | CR201_G0025573 | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (529 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa) |
| | ENSPPYP00000002678 | annotation not available (281 aa) |
| | CR201_G0030157 | KCNMA1 isoform 84. (265 aa) |
| | VCL | VCL isoform 2. (1134 aa) |
| | UNC5B | UNC5B isoform 2. (658 aa) |
| | FAS | FAS isoform 1. (336 aa) |
| | MYOF | MYOF isoform 2. (1936 aa) |
| | SORBS1 | SORBS1 isoform 10. (1292 aa) |
| | PI4K2A | Phosphatidylinositol 4-kinase type 2 alpha. (479 aa) |
| | KCNQ1 | KCNQ1 isoform 3; Belongs to the potassium channel family. (301 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | ANO1 | Anoctamin. (1056 aa) |
| | CR201_G0031208 | AHNAK isoform 6. (2337 aa) |
| | MS4A1 | Membrane spanning 4-domains A1. (297 aa) |
| | MS4A4A | MS4A4A isoform 1. (182 aa) |
| | P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (396 aa) |
| | LRP4 | LRP4 isoform 2. (1900 aa) |
| | SLC1A2 | Amino acid transporter. (574 aa) |
| | KIF18A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (880 aa) |
| | TPP1 | Tripeptidyl-peptidase 1; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity). (583 aa) |
| | CAVIN3 | Caveolae associated protein 3. (261 aa) |
| | STIM1 | Stromal interaction molecule 1. (685 aa) |
| | LAMTOR1 | Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] (161 aa) |
| | KCNE3 | Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa) |
| | NEU3 | NEU3 isoform 2. (404 aa) |
| | SERPINH1 | Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen (By similarity). Belongs to the serpin family. (418 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (597 aa) |
| | PPP2R1B | PPP2R1B isoform 5. (667 aa) |
| | BACE1 | Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa) |
| | CBL | Cbl proto-oncogene. (905 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | KCNA5 | KCNA5 isoform 1; Belongs to the potassium channel family. (602 aa) |
| | TNFRSF1A | TNFRSF1A isoform 2. (454 aa) |
| | CD4 | CD4 isoform 2. (414 aa) |
| | ENSPPYP00000004797 | annotation not available (276 aa) |
| | LDHB | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa) |
| | CNTN1 | CNTN1 isoform 3. (1018 aa) |
| | FAIM2 | Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas- induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. Plays a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development (By similarity). (316 aa) |
| | MYO1A | MYO1A isoform 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (827 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | GLIPR1L1 | GLIPR1L1 isoform 2; Belongs to the CRISP family. (233 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1173 aa) |
| | SELPLG | SELPLG isoform 1. (402 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (434 aa) |
| | CR201_G0000874 | P2RX7 isoform 7. (101 aa) |
| | NOS1 | NOS1 isoform 2. (1456 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | ORAI1 | ORAI1 isoform 1. (297 aa) |
| | SCARB1 | SCARB1 isoform 7; Belongs to the CD36 family. (471 aa) |
| | TRPC4 | TRPC4 isoform 8. (893 aa) |
| | STOML3 | STOML3 isoform 1. (291 aa) |
| | HTR2A | HTR2A isoform 2. (353 aa) |
| | AKAP6 | A-kinase anchoring protein 6. (2319 aa) |
| | AKAP5 | A-kinase anchoring protein 5. (427 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] (463 aa) |
| | CHRNA7 | CHRNA7 isoform 8. (502 aa) |
| | ANXA2 | Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9; Belongs to the annexin family. (339 aa) |
| | CLN6 | CLN6 transmembrane ER protein. (311 aa) |
| | STOML1 | STOML1 isoform 1. (398 aa) |
| | CSK | Tyrosine-protein kinase. (437 aa) |
| | CHRNA3 | Cholinergic receptor nicotinic alpha 3 subunit. (505 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | GP2 | GP2 isoform 2. (561 aa) |
| | LAT | LAT isoform 2. (233 aa) |
| | CD19 | CD19 isoform 3. (557 aa) |
| | CLN3 | Battenin. (438 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) |
| | ITGAM | ITGAM isoform 1; Belongs to the integrin alpha chain family. (1014 aa) |
| | SLC6A2 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (616 aa) |
| | PLLP | PLLP isoform 3. (182 aa) |
| | ADGRG1 | ADGRG1 isoform 22; Belongs to the G-protein coupled receptor 2 family. (687 aa) |
| | CR201_G0015089 | TRADD isoform 2. (234 aa) |
| | CDH15 | CDH15 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (676 aa) |
| | CRK | CRK isoform 1. (204 aa) |
| | MYO1C | MYO1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa) |
| | RTN4RL1 | RTN4RL1 isoform 1. (485 aa) |
| | P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (355 aa) |
| | SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) |
| | RANGRF | RANGRF isoform 1. (186 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa) |
| | SLC6A4 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (595 aa) |
| | PECAM1 | PECAM1 isoform 1. (738 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (877 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (357 aa) |
| | SKAP1 | SKAP1 isoform 2. (347 aa) |
| | SGCA | SGCA isoform 1. (441 aa) |
| | CAVIN1 | CAVIN1 isoform 1. (233 aa) |
| | NPC1 | NPC1 isoform 1. (1243 aa) |
| | RIT2 | Ras like without CAAX 2. (217 aa) |
| | CD226 | CD226 isoform 2. (336 aa) |
| | PLPP2 | PLPP2 isoform 1. (270 aa) |
| | BSG | BSG isoform 4. (264 aa) |
| | PRTN3 | PRTN3 isoform 2; Belongs to the peptidase S1 family. (256 aa) |
| | ARID3A | ARID3A isoform 1. (553 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1305 aa) |
| | FXYD1 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa) |
| | MAG | MAG isoform 1. (627 aa) |
| | CLIP3 | CAP-Gly domain-containing linker protein 3; Functions as a cytoplasmic linker protein. Involved in TGN- endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes (By similarity). (547 aa) |
| | LYPD4 | LYPD4 isoform 1. (151 aa) |
| | CD79A | CD79A isoform 1. (227 aa) |
| | LIPE | LIPE isoform 2. (1068 aa) |
| | CD177 | CD177 isoform 1. (437 aa) |
| | ENSPPYP00000011254 | CD177 antigen. (166 aa) |
| | TEX101 | TEX101 isoform 1. (267 aa) |
| | CBLC | CBLC isoform 2. (430 aa) |
| | EHD2 | EHD2 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (605 aa) |
| | MYADM | Myeloid-associated differentiation marker. (322 aa) |
| | CR201_G0055400 | GP6 isoform 1. (240 aa) |
| | PRNP | Major prion protein; Belongs to the prion family. (253 aa) |
| | HCK | Tyrosine-protein kinase. (449 aa) |
| | SRC | Tyrosine-protein kinase. (553 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (498 aa) |
| | NTSR1 | NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (418 aa) |
| | CXADR | Coxsackievirus and adenovirus receptor homolog; Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induc [...] (365 aa) |
| | APP | APP isoform 3. (736 aa) |
| | KCNE1 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (132 aa) |
| | ITGB2 | Integrin beta. (768 aa) |
| | RTN4R | RTN4R isoform 1. (535 aa) |
| | NFAM1 | NFAM1 isoform 1. (218 aa) |
| | MLC1 | MLC1 isoform 1. (426 aa) |
| | ENSPPYP00000013398 | annotation not available (195 aa) |
| | MAL | Mal, T cell differentiation protein. (153 aa) |
| | MALL | Mal, T cell differentiation protein like. (152 aa) |
| | CR201_G0049459 | CD8A isoform 1. (272 aa) |
| | ADD2 | Beta-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit (By similarity). Belongs to the aldolase class II family. Adducin subfamily. (726 aa) |
| | RHOQ | RHOQ isoform 1. (228 aa) |
| | ADAM17 | ADAM17 isoform 1. (725 aa) |
| | LYPD6 | LY6/PLAUR domain containing 6. (171 aa) |
| | DPP4 | DPP4 isoform 1; Belongs to the peptidase S9B family. (766 aa) |
| | TFPI | Tissue factor pathway inhibitor. (304 aa) |
| | CAVIN2 | Caveolae associated protein 2. (425 aa) |
| | CASP8 | CASP8 isoform 1; Belongs to the peptidase C14A family. (496 aa) |
| | PIKFYVE | PIKFYVE isoform 1. (2088 aa) |
| | ENSPPYP00000014804 | Teratocarcinoma-derived growth factor 1-like. (155 aa) |
| | INPP5D | INPP5D isoform 3. (1144 aa) |
| | TRPM8 | Transient receptor potential cation channel subfamily M member 8. (1104 aa) |
| | CR201_G0049379 | GPC1 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (395 aa) |
| | CBLB | Cbl proto-oncogene B. (982 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa) |
| | HYAL2 | Hyaluronidase. (473 aa) |
| | GNAI2 | GNAI2 isoform 1. (303 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (382 aa) |
| | TDGF1 | TDGF1 isoform 2. (182 aa) |
| | GASK1A | FAM198A isoform 1. (506 aa) |
| | CTNNB1 | CTNNB1 isoform 2. (781 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1523 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | RFTN1 | RFTN1 isoform 3. (623 aa) |
| | EPHB1 | EPHB1 isoform 1. (1057 aa) |
| | PLSCR1 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa) |
| | RAP2B | RAP2B, member of RAS oncogene family. (183 aa) |
| | MME | Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | DLG1 | DLG1 isoform 5; Belongs to the MAGUK family. (922 aa) |
| | TLR1 | Toll like receptor 1; Belongs to the Toll-like receptor family. (786 aa) |
| | TLR6 | Toll-like receptor. (796 aa) |
| | HPSE | HPSE isoform 1. (545 aa) |
| | ABCG2 | ABCG2 isoform 2. (625 aa) |
| | LAMTOR3 | Ragulator complex protein LAMTOR3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP k [...] (124 aa) |
| | ANK2 | ANK2 isoform 1. (4018 aa) |
| | TLR2 | Toll-like receptor. (783 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (576 aa) |
| | ADCY2 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1013 aa) |
| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa) |
| | ENSPPYP00000017286 | annotation not available (283 aa) |
| | IL6ST | IL6ST isoform 1. (935 aa) |
| | F2R | F2R isoform 1; Belongs to the G-protein coupled receptor 1 family. (389 aa) |
| | RGMB | RGMB isoform 2. (591 aa) |
| | EFNA5 | EFNA5 isoform 1; Belongs to the ephrin family. (228 aa) |
| | VDAC1 | VDAC1 isoform 1. (232 aa) |
| | CTNNA1 | CTNNA1 isoform 1. (905 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (343 aa) |
| | ADRA1B | ADRA1B isoform 3. (517 aa) |
| | LCP2 | LCP2 isoform 3. (534 aa) |
| | UNC5A | UNC5A isoform 1. (840 aa) |
| | SLC34A1 | SLC34A1 isoform 3. (616 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | ADTRP | ADTRP isoform 2. (256 aa) |
| | CR201_G0042455 | GABBR1 isoform 2. (710 aa) |
| | TNF | Tumor necrosis factor ligand 1F; Belongs to the tumor necrosis factor family. (233 aa) |
| | TREM2 | TREM2 isoform 1. (202 aa) |
| | BVES | Blood vessel epicardial substance. (360 aa) |
| | CD24 | CD24 isoform 1. (165 aa) |
| | SMPD2 | SMPD2 isoform 1. (577 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | GJA1 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa) |
| | SYNJ2 | SYNJ2 isoform 1. (1489 aa) |
| | EZR | EZR isoform 1. (586 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | CARD11 | CARD11 isoform 1. (1155 aa) |
| | LAMTOR4 | Ragulator complex protein LAMTOR4, N-terminally processed; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity). (99 aa) |
| | LAT2 | Linker for activation of T cells family member 2. (244 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | ADCY1 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (636 aa) |
| | ADCYAP1R1 | ADCYAP1R1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (487 aa) |
| | AQP1 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (323 aa) |
| | ABCB4 | ABCB4 isoform 3. (1223 aa) |
| | CD36 | CD36 isoform 15; Belongs to the CD36 family. (472 aa) |
| | PRKAR2B | PRKAR2B isoform 1. (390 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa) |
| | CAV1 | Caveolin-1; Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt [...] (178 aa) |
| | KCND2 | KCND2 isoform 1; Belongs to the potassium channel family. (630 aa) |
| | PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (513 aa) |
| | NOS3 | NOS3 isoform 2. (833 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa) |
| | DLC1 | DLC1 isoform 1. (1515 aa) |
| | TNFRSF10A | TNFRSF10A isoform 1. (468 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (427 aa) |
| | PTK2B | PTK2B isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | ERLIN2 | Erlin-2; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol- accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (By similarity). (380 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (697 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | SDCBP | SDCBP isoform 3. (297 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa) |
| | PAG1 | PAG1 isoform 1. (376 aa) |
| | BAALC | BAALC binder of MAP3K1 and KLF4. (145 aa) |
| | ANGPT1 | ANGPT1 isoform 2. (498 aa) |
| | MAL2 | Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway (By similarity). (176 aa) |
| | HAS2 | HAS2 isoform 1. (511 aa) |
| | ANXA13 | Annexin. (355 aa) |
| | ADCY8 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) |
| | ARC | Activity regulated cytoskeleton associated protein. (396 aa) |
| | LY6K | LY6K isoform 1. (223 aa) |
| | STOML2 | STOML2 isoform 3. (356 aa) |
| | CR201_G0001936 | TEK isoform 5. (1014 aa) |
| | JAK2 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1132 aa) |
| | SLC1A1 | Amino acid transporter. (524 aa) |
| | PTCH1 | PTCH1 isoform 7. (1429 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) |
| | CAVIN4 | CAVIN4 isoform 1. (356 aa) |
| | ABCA1 | ABCA1 isoform 1. (2234 aa) |
| | STOM | STOM isoform 3. (288 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | ARID3C | ARID3C isoform 1. (313 aa) |
| | GPM6B | GPM6B isoform 6. (329 aa) |
| | DMD | DMD isoform 3. (3618 aa) |
| | HDAC6 | HDAC6 isoform 2. (1208 aa) |
| | ATP7A | ATPase copper transporting alpha. (1500 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | TRPC5 | Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (158 aa) |
| | PLVAP | PLVAP isoform 1. (429 aa) |
| | BST2 | BST2 isoform 1. (200 aa) |
| | LRRK2 | LRRK2 isoform 3. (1560 aa) |
| | ENSPPYP00000024124 | annotation not available (225 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1000 aa) |
| | EFHD2 | EFHD2 isoform 1. (254 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | FLOT1 | Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa) |
| | OLR1 | Oxidized low density lipoprotein receptor 1. (273 aa) |
