STRINGSTRING
RHOA RHOA CR201_G0002480 CR201_G0002480 OPHN1 OPHN1 MSN MSN CDC42 CDC42 TTC8 TTC8 MYO9A MYO9A FOXF1 FOXF1 IFT20 IFT20 SLC9A3R1 SLC9A3R1 LAMA1 LAMA1 SYNE4 SYNE4 CAMSAP3 CAMSAP3 WNT5A WNT5A FAT1 FAT1 PTK7 PTK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOATransforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] (196 aa)
CR201_G0002480LAMA1 isoform 5. (479 aa)
OPHN1OPHN1 isoform 1. (802 aa)
MSNMSN isoform 6. (577 aa)
CDC42Cell division cycle 42. (191 aa)
TTC8TTC8 isoform 1. (505 aa)
MYO9AMYO9A isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2521 aa)
FOXF1FOXF1 isoform 1. (380 aa)
IFT20IFT20 isoform 6. (158 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (357 aa)
LAMA1LAMA1 isoform 1. (842 aa)
SYNE4SYNE4 isoform 6. (404 aa)
CAMSAP3CAMSAP3 isoform 2. (844 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (473 aa)
FAT1FAT1 isoform 1. (4591 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1030 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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