STRINGSTRING
CHRNA9 CHRNA9 HAND2 HAND2 EDNRA EDNRA BBS7 BBS7 PKD2 PKD2 REST REST WDR19 WDR19 CLRN2 CLRN2 NKX3-2 NKX3-2 OTOP1 OTOP1 MSX1 MSX1 DLG1 DLG1 HES1 HES1 CCDC39 CCDC39 CR201_G0007803 CR201_G0007803 CLRN1 CLRN1 ZIC1 ZIC1 PLS1 PLS1 FOXL2 FOXL2 RARB RARB TGFBR2 TGFBR2 CTNNB1 CTNNB1 CR201_G0034913 CR201_G0034913 SETD2 SETD2 WNT5A WNT5A HESX1 HESX1 LRIG1 LRIG1 ARL13B ARL13B IFT57 IFT57 GATA2 GATA2 GBX2 GBX2 IHH IHH FZD5 FZD5 SATB2 SATB2 FRZB FRZB PRKRA PRKRA HOXD3 HOXD3 HOXD9 HOXD9 HOXD10 HOXD10 CR201_G0017164 CR201_G0017164 SP3 SP3 DLX2 DLX2 MYO3B MYO3B BBS5 BBS5 ACVR1 ACVR1 INSIG2 INSIG2 ID2 ID2 OSR1 OSR1 IFT172 IFT172 SIX3 SIX3 SIX2 SIX2 EFEMP1 EFEMP1 OTX1 OTX1 WDPCP WDPCP VAX2 VAX2 ATP6V1B1 ATP6V1B1 NOTO NOTO ENSPPYP00000013398 ENSPPYP00000013398 TRIOBP TRIOBP BCR BCR ENSPPYP00000012962 ENSPPYP00000012962 TBX1 TBX1 SOD1 SOD1 BMP7 BMP7 IFT52 IFT52 MAFB MAFB FUZ FUZ TEAD2 TEAD2 HPN HPN TSHZ1 TSHZ1 SMAD2 SMAD2 TTC39C TTC39C HOXB9 HOXB9 HOXB7 HOXB7 HOXB6 HOXB6 HOXB5 HOXB5 HOXB4 HOXB4 HOXB2 HOXB2 HOXB1 HOXB1 TBX2 TBX2 EIF4A3 EIF4A3 CCDC40 CCDC40 MYO15B MYO15B USH1G USH1G SLC9A3R1 SLC9A3R1 RPL38 RPL38 SOX9 SOX9 PCGF2 PCGF2 TCAP TCAP NAGLU NAGLU FZD2 FZD2 WNT9B WNT9B NOG NOG LHX1 LHX1 MYO15A MYO15A CR201_G0035363 CR201_G0035363 DVL2 DVL2 FOXF1 FOXF1 CR201_G0036821 CR201_G0036821 IRX5 IRX5 TBX6 TBX6 MAPK3 MAPK3 IFT140 IFT140 MESP1 MESP1 ALDH1A3 ALDH1A3 STRA6 STRA6 BBS4 BBS4 SMAD3 SMAD3 FBN1 FBN1 CR201_G0045973 CR201_G0045973 GSC GSC ASB2 ASB2 TSHR TSHR TGFB3 TGFB3 PSEN1 PSEN1 CR201_G0009767 CR201_G0009767 SIX4 SIX4 SIX1 SIX1 BMP4 BMP4 FOXG1 FOXG1 MMP14 MMP14 CR201_G0055387 CR201_G0055387 SLITRK6 SLITRK6 SETDB2 SETDB2 LOC100442324 LOC100442324 FGF9 FGF9 GJB6 GJB6 KDM2B KDM2B TBX3 TBX3 FOXN4 FOXN4 CHST11 CHST11 CEP290 CEP290 RYR2 RYR2 WNT3A WNT3A HLX HLX PROX1 PROX1 FLVCR1 FLVCR1 PRRX1 PRRX1 VANGL2 VANGL2 EFNA1 EFNA1 SLC39A1 SLC39A1 TBX15 TBX15 HIPK1 HIPK1 ALX3 ALX3 COL11A1 COL11A1 STIL STIL KCNQ4 KCNQ4 PHACTR4 PHACTR4 GRHL3 GRHL3 MFAP2 MFAP2 EPHA2 EPHA2 DVL1 DVL1 GATA3 GATA3 ITGA8 ITGA8 MYO3A MYO3A ZEB1 ZEB1 CR201_G0030294 CR201_G0030294 CDH23 CDH23 NODAL NODAL PCDH15 PCDH15 PAX2 PAX2 PDZD7 PDZD7 LBX1 LBX1 CR201_G0023542 CR201_G0023542 SUFU SUFU FGFR2 FGFR2 HMX3 HMX3 HMX2 HMX2 TH TH KCNQ1 KCNQ1 APLNR APLNR ALX4 ALX4 PAX6 PAX6 USH1C USH1C MICAL2 MICAL2 CHRNA10 CHRNA10 C2CD3 C2CD3 WNT11 WNT11 CR201_G0023224 CR201_G0023224 YAP1 YAP1 DSCAML1 DSCAML1 CR201_G0026161 CR201_G0026161 TULP3 TULP3 MFAP5 MFAP5 COL2A1 COL2A1 WNT1 WNT1 RARG RARG HOXC11 HOXC11 HOXC9 HOXC9 HOXC4 HOXC4 GLI1 GLI1 LRIG3 LRIG3 FRS2 FRS2 PTPRQ PTPRQ MYF5 MYF5 ALX1 ALX1 OVOL2 OVOL2 EPHB2 EPHB2 TMED2 TMED2 FOXH1 FOXH1 CR201_G0011157 CR201_G0011157 SEC24B SEC24B CLUAP1 CLUAP1 NEUROD1 NEUROD1 NDRG4 NDRG4 HOXA1 HOXA1 MIB1 MIB1 MAPK1 MAPK1 ZIC3 ZIC3 POU3F4 POU3F4 MED12 MED12 KDM6A KDM6A TPRN TPRN NOTCH1 NOTCH1 ENG ENG CRB2 CRB2 WHRN WHRN TGFBR1 TGFBR1 FOXE1 FOXE1 PAX5 PAX5 SCRIB SCRIB CTHRC1 CTHRC1 FZD6 FZD6 CR201_G0028244 CR201_G0028244 OSR2 OSR2 MMP16 MMP16 RDH10 RDH10 EYA1 EYA1 CHD7 CHD7 SOX17 SOX17 FZD3 FZD3 GATA4 GATA4 WDR60 WDR60 SHH SHH INSIG1 INSIG1 HIPK2 HIPK2 SMO SMO WNT16 WNT16 DLX6 DLX6 DLX5 DLX5 TWIST1 TWIST1 HOXA2 HOXA2 HOXA3 HOXA3 HOXA4 HOXA4 HOXA5 HOXA5 HOXA11 HOXA11 TBX20 TBX20 GLI3 GLI3 CR201_G0048550 CR201_G0048550 DLL1 DLL1 TBXT TBXT MTHFD1L MTHFD1L CITED2 CITED2 AHI1 AHI1 TCF21 TCF21 SOBP SOBP TBX18 TBX18 MYO6 MYO6 ENSPPYP00000018739 ENSPPYP00000018739 LRRC1 LRRC1 RUNX2 RUNX2 SRF SRF PTK7 PTK7 MDFI MDFI SLC44A4 SLC44A4 EDN1 EDN1 TFAP2A TFAP2A BLOC1S5 BLOC1S5 FOXF2 FOXF2 CR201_G0004819 CR201_G0004819 FOXI1 FOXI1 HAND1 HAND1 NDST1 NDST1 POU4F3 POU4F3 GRXCR2 GRXCR2 NEUROG1 NEUROG1 TIFAB TIFAB FBN2 FBN2 MEF2C MEF2C FGF10 FGF10 NIPBL NIPBL ATOH1 ATOH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHRNA9CHRNA9 isoform 1. (479 aa)
HAND2HAND2 isoform 1. (217 aa)
EDNRAEDNRA isoform 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
PKD2PKD2 isoform 1. (968 aa)
RESTREST isoform 6. (1250 aa)
WDR19WDR19 isoform 1. (1273 aa)
CLRN2CLRN2 isoform 1. (249 aa)
NKX3-2NKX3-2 isoform 1. (333 aa)
OTOP1OTOP1 isoform 1. (611 aa)
MSX1MSX1 isoform 1. (261 aa)
DLG1DLG1 isoform 5; Belongs to the MAGUK family. (922 aa)
HES1HES1 isoform 1. (198 aa)
CCDC39CCDC39 isoform 3. (753 aa)
CR201_G0007803SHOX2 isoform 5. (151 aa)
CLRN1CLRN1 isoform 2. (232 aa)
ZIC1ZIC1 isoform 2. (65 aa)
PLS1PLS1 isoform 1. (631 aa)
FOXL2FOXL2 isoform 1. (376 aa)
RARBRARB isoform 2. (526 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CTNNB1CTNNB1 isoform 2. (781 aa)
CR201_G0034913TMIE isoform 1. (193 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (473 aa)
HESX1HESX homeobox 1. (185 aa)
LRIG1LRIG1 isoform 3. (973 aa)
ARL13BARL13B isoform 4. (428 aa)
IFT57Intraflagellar transport 57. (429 aa)
GATA2GATA2 isoform 1. (408 aa)
GBX2GBX2 isoform 1. (173 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
SATB2DNA-binding protein SATB. (733 aa)
FRZBSecreted frizzled-related protein 3; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development (By similarity). (325 aa)
PRKRAPRKRA isoform 1. (312 aa)
HOXD3HOXD3 isoform 3. (432 aa)
HOXD9HOXD9 isoform 1. (300 aa)
HOXD10HOXD10 isoform 3. (340 aa)
CR201_G0017164HOXD11 isoform 2. (143 aa)
SP3SP3 isoform 2. (689 aa)
DLX2Distal-less homeobox 2. (328 aa)
MYO3BMYO3B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1306 aa)
BBS5T0057746 isoform 1. (341 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
INSIG2Insulin-induced gene 2 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR (By similarity). (216 aa)
ID2DNA-binding protein inhibitor ID-2; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the C [...] (134 aa)
OSR1OSR1 isoform 1. (265 aa)
IFT172IFT172 isoform 1. (1728 aa)
SIX3SIX3 isoform 1. (210 aa)
SIX2SIX homeobox 2. (291 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (493 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
WDPCPWDPCP isoform 4. (745 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
ATP6V1B1V-type proton ATPase subunit B, brain isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (509 aa)
NOTONOTO isoform 1. (243 aa)
ENSPPYP00000013398annotation not available (195 aa)
TRIOBPTRIOBP isoform 1. (2199 aa)
BCRBCR isoform 1. (1271 aa)
ENSPPYP00000012962annotation not available (96 aa)
TBX1TBX1 isoform 2. (213 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (130 aa)
BMP7Bone morphogenetic protein 7. (365 aa)
IFT52IFT52 isoform 1. (448 aa)
MAFBMAF bZIP transcription factor B. (323 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
TEAD2TEA domain transcription factor 2. (447 aa)
HPNSerine protease hepsin non-catalytic chain; Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2 (By similarity). (417 aa)
TSHZ1TSHZ1 isoform 3. (1077 aa)
SMAD2Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator [...] (467 aa)
TTC39CTetratricopeptide repeat domain 39C. (522 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
HOXB7HOXB7 isoform 2. (217 aa)
HOXB6HOXB6 isoform 1. (224 aa)
HOXB5HOXB5 isoform 1. (269 aa)
HOXB4HOXB4 isoform 1. (251 aa)
HOXB2HOXB2 isoform 1. (356 aa)
HOXB1HOXB1 isoform 1. (170 aa)
TBX2TBX2 isoform 1. (588 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
CCDC40CCDC40 isoform 3. (1140 aa)
MYO15BMYO15B isoform 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1560 aa)
USH1GUSH1G isoform 1. (517 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (357 aa)
RPL38Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
SOX9SRY-box transcription factor 9. (509 aa)
PCGF2PCGF2 isoform 1. (347 aa)
TCAPTCAP isoform 1. (167 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (342 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LHX1LHX1 isoform 1. (406 aa)
MYO15AMYO15A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3281 aa)
CR201_G0035363NTN1 isoform 1. (337 aa)
DVL2DVL2 isoform 1. (677 aa)
FOXF1FOXF1 isoform 1. (380 aa)
CR201_G0036821Dynein assembly factor 1, axonemal. (670 aa)
IRX5Iroquois homeobox 5. (483 aa)
TBX6TBX6 isoform 2. (436 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa)
IFT140Intraflagellar transport 140. (1462 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (269 aa)
ALDH1A3ALDH1A3 isoform 2; Belongs to the aldehyde dehydrogenase family. (431 aa)
STRA6Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...] (666 aa)
BBS4BBS4 isoform 3. (495 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
FBN1FBN1 isoform 1. (2871 aa)
CR201_G0045973STRC isoform 2. (1473 aa)
GSCGoosecoid homeobox. (257 aa)
ASB2ASB2 isoform 6. (553 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
PSEN1Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] (463 aa)
CR201_G0009767HIF1A isoform 5. (735 aa)
SIX4SIX4 isoform 1. (698 aa)
SIX1SIX homeobox 1. (284 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
FOXG1FOXG1 isoform 8. (440 aa)
MMP14Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...] (582 aa)
CR201_G0055387PhoLip_ATPase_N domain-containing protein. (108 aa)
SLITRK6SLITRK6 isoform 1. (395 aa)
SETDB2SETDB2 isoform 3. (707 aa)
LOC100442324Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (725 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
KDM2BKDM2B isoform 3. (1280 aa)
TBX3T-box transcription factor 3. (743 aa)
FOXN4FOXN4 isoform 1. (517 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
CEP290CEP290 isoform 4. (2481 aa)
RYR2RYR2 isoform 1. (4546 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
HLXH2.0 like homeobox. (496 aa)
PROX1Prospero homeobox 1. (737 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
PRRX1PRRX1 isoform 3. (216 aa)
VANGL2Vang-like protein. (390 aa)
EFNA1EFNA1 isoform 1; Belongs to the ephrin family. (205 aa)
SLC39A1SLC39A1 isoform 1. (324 aa)
TBX15T-box transcription factor 15. (496 aa)
HIPK1HIPK1 isoform 4. (1209 aa)
ALX3ALX homeobox 3. (343 aa)
COL11A1COL11A1 isoform 4. (1573 aa)
STILSTIL isoform 3. (1288 aa)
KCNQ4KCNQ4 isoform 1; Belongs to the potassium channel family. (576 aa)
PHACTR4Phosphatase and actin regulator 4; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to [...] (687 aa)
GRHL3GRHL3 isoform 2. (602 aa)
MFAP2MFAP2 isoform 3. (214 aa)
EPHA2EPHA2 isoform 1. (959 aa)
DVL1DVL1 isoform 2. (594 aa)
GATA3GATA binding protein 3. (444 aa)
ITGA8ITGA8 isoform 1; Belongs to the integrin alpha chain family. (948 aa)
MYO3AMYO3A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1575 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1125 aa)
CR201_G0030294CDH23 isoform 6. (250 aa)
CDH23CDH23 isoform 1. (2498 aa)
NODALNodal growth differentiation factor. (347 aa)
PCDH15PCDH15 isoform 18. (1163 aa)
PAX2PAX2 isoform 3. (388 aa)
PDZD7PDZ domain-containing protein 7; In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1. (477 aa)
LBX1Ladybird homeobox 1. (281 aa)
CR201_G0023542Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
FGFR2Fibroblast growth factor receptor. (656 aa)
HMX3HMX3 isoform 1. (323 aa)
HMX2HMX2 isoform 1. (266 aa)
THTH isoform 6. (522 aa)
KCNQ1KCNQ1 isoform 3; Belongs to the potassium channel family. (301 aa)
APLNRAPLNR isoform 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
ALX4ALX4 isoform 1. (407 aa)
PAX6PAX6 isoform 13. (266 aa)
USH1CUSH1C isoform 9. (403 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
C2CD3C2CD3 isoform 3. (1921 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CR201_G0023224MYO7A isoform 2. (1350 aa)
YAP1YAP1 isoform 2. (326 aa)
DSCAML1DSCAML1 isoform 2. (2118 aa)
CR201_G0026161USH1C isoform 8. (559 aa)
TULP3TULP3 isoform 2. (439 aa)
MFAP5Microfibril associated protein 5. (163 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
RARGRARG isoform 5. (469 aa)
HOXC11HOXC11 isoform 1. (304 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
HOXC4HOXC4 isoform 1. (146 aa)
GLI1GLI family zinc finger 1. (1106 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1119 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
PTPRQPTPRQ isoform 5. (154 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
ALX1ALX homeobox 1. (326 aa)
OVOL2Ovo like zinc finger 2. (289 aa)
EPHB2EPHB2 isoform 2. (792 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
FOXH1FOXH1 isoform 1. (366 aa)
CR201_G0011157PAX6 isoform 63. (257 aa)
SEC24BSEC24B isoform 3. (1137 aa)
CLUAP1CLUAP1 isoform 4. (236 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
NDRG4NDRG4 isoform 31. (401 aa)
HOXA1HOXA1 isoform 2. (197 aa)
MIB1MIB1 isoform 1. (539 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (158 aa)
ZIC3Zic family member 3. (466 aa)
POU3F4POU domain protein. (361 aa)
MED12MED12 isoform 3. (2178 aa)
KDM6AUTY isoform 5. (1350 aa)
TPRNTPRN isoform 2. (404 aa)
NOTCH1NOTCH1 isoform 1. (2107 aa)
ENGENG isoform 3. (668 aa)
CRB2CRB2 isoform 2. (637 aa)
WHRNWHRN isoform 2. (907 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
FOXE1FOXE1 isoform 1. (371 aa)
PAX5PAX5 isoform 1. (391 aa)
SCRIBSCRIB isoform 2. (1472 aa)
CTHRC1CTHRC1 isoform 3. (232 aa)
FZD6Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (706 aa)
CR201_G0028244GRHL2 isoform 1. (493 aa)
OSR2OSR2 isoform 10. (312 aa)
MMP16MMP16 isoform 1. (606 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
SOX17SRY-box transcription factor 17. (416 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
GATA4GATA binding protein 4. (442 aa)
WDR60WD repeat domain 60. (1067 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
HIPK2HIPK2 isoform 2. (1136 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DLX6DLX6 isoform 1. (230 aa)
DLX5Distal-less homeobox 5. (289 aa)
TWIST1Twist family bHLH transcription factor 1. (203 aa)
HOXA2HOXA2 isoform 1. (374 aa)
HOXA3HOXA3 isoform 3. (443 aa)
HOXA4HOXA4 isoform 1. (319 aa)
HOXA5HOXA5 isoform 1. (381 aa)
HOXA11HOXA11 isoform 2. (315 aa)
TBX20TBX20 isoform 1. (447 aa)
GLI3GLI3 isoform 3. (1580 aa)
CR201_G0048550PPP1R35 isoform 3. (127 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
TBXTT-box transcription factor T. (435 aa)
MTHFD1LMTHFD1L isoform 1. (978 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
AHI1AHI1 isoform 11. (1046 aa)
TCF21Transcription factor 21. (179 aa)
SOBPSOBP isoform 1. (873 aa)
TBX18T-box transcription factor 18. (607 aa)
MYO6MYO6 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
ENSPPYP00000018739annotation not available (186 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (589 aa)
SRFSerum response factor. (508 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1030 aa)
MDFIMDFI isoform 3. (246 aa)
SLC44A4SLC44A4 isoform 2; Belongs to the CTL (choline transporter-like) family. (712 aa)
EDN1EDN1 isoform 1. (212 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (115 aa)
FOXF2FOXF2 isoform 1. (184 aa)
CR201_G0004819NKX2-5 isoform 1. (210 aa)
FOXI1FOXI1 isoform 1. (378 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
POU4F3POU domain protein. (338 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (248 aa)
NEUROG1NEUROG1 isoform 1. (237 aa)
TIFABTIFAB isoform 1. (162 aa)
FBN2FBN2 isoform 1. (2909 aa)
MEF2CMyocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (441 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
NIPBLNipped-B protein. (2684 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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