STRINGSTRING
ENSPPYP00000013398 ENSPPYP00000013398 BTNL10 BTNL10 PTPRC PTPRC DENND1B DENND1B RC3H1 RC3H1 CD247 CD247 VTCN1 VTCN1 PTPN22 PTPN22 BCL10 BCL10 PDE4B PDE4B FYB2 FYB2 ENSPPYP00000001595 ENSPPYP00000001595 EIF2B3 EIF2B3 ERMAP ERMAP TMEM269 TMEM269 ZC3H12A ZC3H12A LCK LCK KHDRBS1 KHDRBS1 THEMIS2 THEMIS2 ZNF683 ZNF683 PIK3CD PIK3CD GATA3 GATA3 HRAS HRAS TRAF6 TRAF6 CD3E CD3E CD3D CD3D CD3G CD3G THY1 THY1 PTPN6 PTPN6 CACNB3 CACNB3 SPPL3 SPPL3 EIF2B1 EIF2B1 RNF31 RNF31 PSEN1 PSEN1 EIF2B2 EIF2B2 CD276 CD276 CSK CSK BCAR1 BCAR1 PLCG2 PLCG2 SKAP1 SKAP1 MALT1 MALT1 STK11 STK11 PRAM1 PRAM1 FCHO1 FCHO1 NFKBID NFKBID PRKD2 PRKD2 RBCK1 RBCK1 PLCG1 PLCG1 ADA ADA ICOSLG ICOSLG ZAP70 ZAP70 CR201_G0049459 CR201_G0049459 EIF2B4 EIF2B4 CACNB4 CACNB4 ENSPPYP00000014637 ENSPPYP00000014637 CTLA4 CTLA4 INPP5D INPP5D HHLA2 HHLA2 CBLB CBLB RFTN1 RFTN1 EIF2B5 EIF2B5 TXK TXK TEC TEC FYB1 FYB1 PDE4D PDE4D ITK ITK LCP2 LCP2 BTNL3 BTNL3 BTNL9 BTNL9 BTN1A1 BTN1A1 HLA-A HLA-A CR201_G0016196 CR201_G0016196 TNFRSF21 TNFRSF21 FYN FYN THEMIS THEMIS BTNL2 BTNL2 CR201_G0016219 CR201_G0016219 CR201_G0042422 CR201_G0042422 ENSPPYP00000019322 ENSPPYP00000019322 CR201_G0055693 CR201_G0055693 BRAF BRAF IKBKB IKBKB RIPK2 RIPK2 SHB SHB STOML2 STOML2 RC3H2 RC3H2 CR201_G0027499 CR201_G0027499 ABL1 ABL1 FOXP3 FOXP3 IKBKG IKBKG PIK3CA PIK3CA WNK1 WNK1 MAPK1 MAPK1 HLA-DPB1 HLA-DPB1 NFKBIZ NFKBIZ CRKL CRKL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPYP00000013398annotation not available (195 aa)
BTNL10Butyrophilin-like protein 10. (231 aa)
PTPRCPTPRC isoform 2. (1267 aa)
DENND1BDENND1B isoform 3. (425 aa)
RC3H1RC3H1 isoform 1. (1094 aa)
CD247CD247 isoform 2. (165 aa)
VTCN1VTCN1 isoform 1. (191 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
BCL10BCL10 isoform 1. (263 aa)
PDE4BPhosphodiesterase. (736 aa)
FYB2FYN binding protein 2. (729 aa)
ENSPPYP00000001595LOW QUALITY PROTEIN: selection and upkeep of intraepithelial T-cells protein 1. (232 aa)
EIF2B3EIF2B3 isoform 1. (396 aa)
ERMAPERMAP isoform 1. (475 aa)
TMEM269TMEM269 isoform 3. (290 aa)
ZC3H12AZC3H12A isoform 1. (599 aa)
LCKTyrosine-protein kinase. (487 aa)
KHDRBS1KHDRBS1 isoform 2. (547 aa)
THEMIS2Thymocyte selection associated family member 2. (642 aa)
ZNF683Zinc finger protein 683. (524 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1027 aa)
GATA3GATA binding protein 3. (444 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (604 aa)
CD3ECD3E isoform 2. (198 aa)
CD3DCD3D isoform 1. (171 aa)
CD3GCD3G isoform 1. (182 aa)
THY1Thy-1 cell surface antigen. (161 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
SPPL3SPPL3 isoform 1. (383 aa)
EIF2B1Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
RNF31T0114761 isoform 1. (1053 aa)
PSEN1Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] (463 aa)
EIF2B2EIF2B2 isoform 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
CD276CD276 isoform 13. (534 aa)
CSKTyrosine-protein kinase. (437 aa)
BCAR1BCAR1 isoform 1. (849 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1230 aa)
SKAP1SKAP1 isoform 2. (347 aa)
MALT1MALT1 isoform 1. (774 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
PRAM1LOW QUALITY PROTEIN: PML-RARA-regulated adapter molecule 1. (644 aa)
FCHO1FCHO1 isoform 1. (898 aa)
NFKBIDNFKBID isoform 3. (440 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (801 aa)
RBCK1RBCK1 isoform 5. (509 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
ADAAdenosine deaminase. (363 aa)
ICOSLGICOSLG isoform 1. (322 aa)
ZAP70Tyrosine-protein kinase. (559 aa)
CR201_G0049459CD8A isoform 1. (272 aa)
EIF2B4EIF2B4 isoform 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (553 aa)
CACNB4CACNB4 isoform 16. (487 aa)
ENSPPYP00000014637annotation not available (137 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
INPP5DINPP5D isoform 3. (1144 aa)
HHLA2HHLA2 isoform 4. (416 aa)
CBLBCbl proto-oncogene B. (982 aa)
RFTN1RFTN1 isoform 3. (623 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
TXKTyrosine-protein kinase. (527 aa)
TECTyrosine-protein kinase. (515 aa)
FYB1FYB1 isoform 4. (828 aa)
PDE4DPhosphodiesterase. (679 aa)
ITKTyrosine-protein kinase. (620 aa)
LCP2LCP2 isoform 3. (534 aa)
BTNL3BTNL8 isoform 2. (412 aa)
BTNL9BTNL9 isoform 1. (539 aa)
BTN1A1Butyrophilin subfamily 1 member A1. (494 aa)
HLA-APopy Class I histocompatibility antigen, A-1 alpha chain. (365 aa)
CR201_G0016196HLA-DQB1 isoform 5. (304 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
FYNTyrosine-protein kinase. (537 aa)
THEMISThymocyte selection associated. (641 aa)
BTNL2BTNL2 isoform 4. (454 aa)
CR201_G0016219HLA-DPB1 isoform 1. (283 aa)
CR201_G0042422HLA-G isoform 2; Belongs to the MHC class I family. (365 aa)
ENSPPYP00000019322annotation not available (157 aa)
CR201_G0055693HLA-B isoform 1; Belongs to the MHC class I family. (362 aa)
BRAFBRAF isoform 1. (765 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (697 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
SHBSHB isoform 1. (398 aa)
STOML2STOML2 isoform 3. (356 aa)
RC3H2RC3H2 isoform 1. (1143 aa)
CR201_G0027499ABL1 isoform 3. (48 aa)
ABL1Tyrosine-protein kinase. (948 aa)
FOXP3FOXP3 isoform 1. (431 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (832 aa)
WNK1WNK1 isoform 4. (2694 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (158 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
NFKBIZNFKBIZ isoform 5. (718 aa)
CRKLCRKL isoform 1. (251 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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