STRINGSTRING
CFTR CFTR SH3TC2 SH3TC2 FCHSD1 FCHSD1 PDLIM4 PDLIM4 MCTP1 MCTP1 SCAMP1 SCAMP1 SNX18 SNX18 CLCN3 CLCN3 ANK2 ANK2 NSG1 NSG1 SORCS2 SORCS2 SH3TC1 SH3TC1 MELTF MELTF TFRC TFRC ATP13A3 ATP13A3 ATP13A4 ATP13A4 TNIK TNIK RAP2B RAP2B SLC9A9 SLC9A9 AMOTL2 AMOTL2 TF TF ACKR4 ACKR4 CMTM6 CMTM6 ACKR2 ACKR2 LTF LTF NISCH NISCH DENND6A DENND6A ADPRH ADPRH BOK BOK RAB17 RAB17 ACKR3 ACKR3 ATG9A ATG9A FZD7 FZD7 ABCB11 ABCB11 WASHC1 WASHC1 PLEKHB2 PLEKHB2 EIPR1 EIPR1 RAB10 RAB10 EHD3 EHD3 CR201_G0003257 CR201_G0003257 RAB11FIP5 RAB11FIP5 VAMP8 VAMP8 INPP4A INPP4A LZTR1 LZTR1 DENND6B DENND6B MLC1 MLC1 PHETA2 PHETA2 PLA2G3 PLA2G3 ITSN1 ITSN1 APP APP ATP9A ATP9A ARFGEF2 ARFGEF2 VPS16 VPS16 TMEM230 TMEM230 LAMP5 LAMP5 SYT5 SYT5 TBC1D17 TBC1D17 EHD2 EHD2 ENSPPYP00000011198 ENSPPYP00000011198 CLIP3 CLIP3 CD22 CD22 RAB8A RAB8A RAB11B RAB11B PLEKHJ1 PLEKHJ1 ABHD17A ABHD17A RELCH RELCH RAB12 RAB12 SNF8 SNF8 UNC13D UNC13D GGA3 GGA3 RAB11FIP4 RAB11FIP4 ARHGAP44 ARHGAP44 STX8 STX8 ACAP1 ACAP1 RABEP1 RABEP1 CR201_G0053168 CR201_G0053168 VPS53 VPS53 CLN3 CLN3 BAIAP3 BAIAP3 LOC100437697 LOC100437697 ST8SIA2 ST8SIA2 VPS33B VPS33B SCAMP5 SCAMP5 SCAMP2 SCAMP2 RAB11A RAB11A TUBGCP4 TUBGCP4 EHD4 EHD4 VIPAS39 VIPAS39 VTI1B VTI1B RAB15 RAB15 AKAP5 AKAP5 ARF6 ARF6 ATP11A ATP11A RAP2A RAP2A ULK1 ULK1 RAB35 RAB35 TPCN1 TPCN1 PHETA1 PHETA1 AQP2 AQP2 SORL1 SORL1 BACE1 BACE1 NEU3 NEU3 FCHSD2 FCHSD2 TPP1 TPP1 DENND2B DENND2B RASSF10 RASSF10 EHD1 EHD1 VPS51 VPS51 INPP5F INPP5F RAB11FIP2 RAB11FIP2 ZFYVE27 ZFYVE27 TBC1D12 TBC1D12 PANK1 PANK1 ITGB1 ITGB1 OPTN OPTN VAMP3 VAMP3 PLA2G5 PLA2G5 LDLRAP1 LDLRAP1 STX12 STX12 C1orf210 C1orf210 RNF11 RNF11 MCOLN2 MCOLN2 RAB13 RAB13 SCAMP3 SCAMP3 SYT11 SYT11 RAB25 RAB25 NTRK1 NTRK1 ACKR1 ACKR1 GPR161 GPR161 RAB29 RAB29 SLC30A10 SLC30A10 RAB4A RAB4A KCNK1 KCNK1 RABGEF1 RABGEF1 LMTK2 LMTK2 RAC1 RAC1 MICALL2 MICALL2 CR201_G0055693 CR201_G0055693 VPS52 VPS52 CR201_G0042422 CR201_G0042422 AVL9 AVL9 DYNC1I1 DYNC1I1 VPS50 VPS50 ATG9B ATG9B TMUB1 TMUB1 ZDHHC2 ZDHHC2 RAB11FIP1 RAB11FIP1 SGK3 SGK3 SLC26A7 SLC26A7 NDRG1 NDRG1 ENSPPYP00000021280 ENSPPYP00000021280 SLC1A1 SLC1A1 MHC-Poab-B MHC-Poab-B CR201_G0055889 CR201_G0055889 STX7 STX7 FIG4 FIG4 TNF TNF HLA-A HLA-A HFE HFE GRIA1 GRIA1 SLC36A2 SLC36A2 ABHD17B ABHD17B SLC31A2 SLC31A2 RAB14 RAB14 ENTR1 ENTR1 CLCN4 CLCN4 SLC9A7 SLC9A7 CR201_G0052920 CR201_G0052920 RAP2C RAP2C SLC9A6 SLC9A6 ATP11C ATP11C RFFL RFFL ABHD17C ABHD17C ATP11B ATP11B SLC11A2 SLC11A2 ABCG1 ABCG1 ENSPPYP00000024753 ENSPPYP00000024753
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second shell of interactors
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proteins of unknown 3D structure
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gene neighborhood
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co-expression
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CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
SH3TC2SH3TC2 isoform 8. (1287 aa)
FCHSD1FCHSD1 isoform 1. (685 aa)
PDLIM4PDZ and LIM domain 4. (330 aa)
MCTP1MCTP1 isoform 5. (774 aa)
SCAMP1Secretory carrier-associated membrane protein. (338 aa)
SNX18Sorting nexin. (624 aa)
CLCN3H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity). (866 aa)
ANK2ANK2 isoform 1. (4018 aa)
NSG1Neuronal vesicle trafficking-associated protein 1; Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatoden [...] (185 aa)
SORCS2SORCS2 isoform 3. (600 aa)
SH3TC1SH3TC1 isoform 7. (1242 aa)
MELTFMELTF isoform 1; Belongs to the transferrin family. (741 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (760 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1207 aa)
ATP13A4Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1151 aa)
TNIKTRAF2 and NCK interacting kinase. (1360 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (619 aa)
AMOTL2AMOTL2 isoform 11. (770 aa)
TFTF isoform 1; Belongs to the transferrin family. (703 aa)
ACKR4Atypical chemokine receptor 4. (350 aa)
CMTM6CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...] (183 aa)
ACKR2ACKR2 isoform 3; Belongs to the G-protein coupled receptor 1 family. (407 aa)
LTFLTF isoform 1; Belongs to the transferrin family. (712 aa)
NISCHNISCH isoform 1. (1505 aa)
DENND6ADENND6A isoform 1. (608 aa)
ADPRHADPRH isoform 1. (357 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
RAB17RAB17 isoform 2. (212 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ATG9AAutophagy-related protein 9A; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H (By similarity). (838 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
ABCB11ABCB11 isoform 1. (1321 aa)
WASHC1WAS protein family homolog 1. (467 aa)
PLEKHB2Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. (222 aa)
EIPR1EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome- associated recycling protein (EARP) complex. (409 aa)
RAB10Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane (By similarity). Regulates, for instance, SLC [...] (199 aa)
EHD3EHD3 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
CR201_G0003257COMMD1 isoform 4. (146 aa)
RAB11FIP5RAB11FIP5 isoform 2. (589 aa)
VAMP8Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] (253 aa)
INPP4AINPP4A isoform 2. (971 aa)
LZTR1Leucine-zipper-like transcriptional regulator 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes. (820 aa)
DENND6BDENND6B isoform 1. (527 aa)
MLC1MLC1 isoform 1. (426 aa)
PHETA2PH domain containing endocytic trafficking adaptor 2. (259 aa)
PLA2G3PLA2G3 isoform 1. (505 aa)
ITSN1ITSN1 isoform 4. (1610 aa)
APPAPP isoform 3. (736 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1022 aa)
ARFGEF2ARFGEF2 isoform 1. (1779 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
TMEM230Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles. Belongs to the TMEM134/TMEM230 family. (120 aa)
LAMP5Lysosome-associated membrane glycoprotein 5; Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain; Belongs to the LAMP family. (261 aa)
SYT5SYT5 isoform 2. (386 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
EHD2EHD2 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (605 aa)
ENSPPYP00000011198annotation not available (173 aa)
CLIP3CAP-Gly domain-containing linker protein 3; Functions as a cytoplasmic linker protein. Involved in TGN- endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes (By similarity). (547 aa)
CD22CD22 isoform 11. (847 aa)
RAB8ARas-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] (207 aa)
RAB11BRAB11B, member RAS oncogene family. (218 aa)
PLEKHJ1PLEKHJ1 isoform 1. (149 aa)
ABHD17AABHD17A isoform 5. (383 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
RAB12RAB12 isoform 1. (340 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (279 aa)
UNC13DUNC13D isoform 1. (1042 aa)
GGA3GGA3 isoform 1. (716 aa)
RAB11FIP4RAB11FIP4 isoform 1. (557 aa)
ARHGAP44ARHGAP44 isoform 2. (736 aa)
STX8STX8 isoform 2. (236 aa)
ACAP1ACAP1 isoform 1. (635 aa)
RABEP1Rabaptin, RAB GTPase binding effector protein 1. (862 aa)
CR201_G0053168T0188308 isoform 2. (1404 aa)
VPS53Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] (770 aa)
CLN3Battenin. (438 aa)
BAIAP3BAIAP3 isoform 3. (1072 aa)
LOC100437697RAB11FIP3 isoform 1. (536 aa)
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (375 aa)
VPS33BVPS33B isoform 1; Belongs to the STXBP/unc-18/SEC1 family. (617 aa)
SCAMP5Secretory carrier-associated membrane protein 5; Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity). (240 aa)
SCAMP2Secretory carrier-associated membrane protein. (329 aa)
RAB11ARas-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] (216 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (658 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
VIPAS39VIPAS39 isoform 6. (433 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
RAB15RAB15 isoform 2. (207 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1159 aa)
RAP2ARas-related protein Rap-2a; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading (By similarity). (197 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (924 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
TPCN1TPCN1 isoform 2. (798 aa)
PHETA1PH domain containing endocytic trafficking adaptor 1. (247 aa)
AQP2AQP2 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SORL1SORL1 isoform 1. (2118 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
NEU3NEU3 isoform 2. (404 aa)
FCHSD2FCH and double SH3 domains 2. (764 aa)
TPP1Tripeptidyl-peptidase 1; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity). (583 aa)
DENND2BSuppression of tumorigenicity 5. (1137 aa)
RASSF10RASSF10 isoform 1. (419 aa)
EHD1EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary v [...] (534 aa)
VPS51VPS51 isoform 3. (303 aa)
INPP5FINPP5F isoform 1. (1037 aa)
RAB11FIP2RAB11 family interacting protein 2. (512 aa)
ZFYVE27Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. Acts as an adapter protein that facilitates the interaction of KIF5A with VAPA, VAPB, [...] (480 aa)
TBC1D12TBC1D12 isoform 1. (772 aa)
PANK1Pantothenate kinase 1. (598 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (887 aa)
OPTNOptineurin; Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection. Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex th [...] (532 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
PLA2G5Phospholipase A(2). (138 aa)
LDLRAP1LDLRAP1 isoform 1. (308 aa)
STX12Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). (274 aa)
C1orf210Chromosome 1 open reading frame 210. (113 aa)
RNF11Ring finger protein 11. (154 aa)
MCOLN2MCOLN2 isoform 1. (532 aa)
RAB13RAB13 isoform 2. (203 aa)
SCAMP3Secretory carrier-associated membrane protein. (347 aa)
SYT11SYT11 isoform 1. (388 aa)
RAB25RAB25, member RAS oncogene family. (213 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ACKR1ACKR1 isoform 1. (336 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (549 aa)
RAB29Ras-related protein Rab-7L1; The small GTPases Rab are key regulators in vesicle trafficking (By similarity). Essential for maintaining the integrity of endosome-trans-Golgi network structure (By similarity). Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner (By similarity). Recruits LRRK2 to the Golgi apparatus and stimulates LRRK2 kinase activity (By similarity). Regulates also neuronal process morphology in the intact cen [...] (203 aa)
SLC30A10Solute carrier family 30 member 10. (485 aa)
RAB4ARAB4A, member RAS oncogene family. (218 aa)
KCNK1Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels, and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa)
RABGEF1RABGEF1 isoform 2. (544 aa)
LMTK2LMTK2 isoform 1. (1474 aa)
RAC1Rac family small GTPase 1. (211 aa)
MICALL2MICALL2 isoform 9. (905 aa)
CR201_G0055693HLA-B isoform 1; Belongs to the MHC class I family. (362 aa)
VPS52VPS52 isoform 4. (723 aa)
CR201_G0042422HLA-G isoform 2; Belongs to the MHC class I family. (365 aa)
AVL9Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family. (648 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
VPS50VPS50 isoform 2. (964 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
TMUB1TMUB1 isoform 1. (321 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (367 aa)
RAB11FIP1RAB11 family interacting protein 1. (1275 aa)
SGK3Serine/threonine-protein kinase Sgk3; Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate [...] (466 aa)
SLC26A7Anion exchange transporter; Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment- specific anion exchanger, specifically chloride. Plays a major role in gastric acid secretion (By similarity); Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (656 aa)
NDRG1NDRG1 isoform 2. (408 aa)
ENSPPYP00000021280annotation not available (466 aa)
SLC1A1Amino acid transporter. (524 aa)
MHC-Poab-BMHC class I antigen; Belongs to the MHC class I family. (323 aa)
CR201_G0055889Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa)
STX7Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). (261 aa)
FIG4FIG4 isoform 1. (891 aa)
TNFTumor necrosis factor ligand 1F; Belongs to the tumor necrosis factor family. (233 aa)
HLA-APopy Class I histocompatibility antigen, A-1 alpha chain. (365 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
GRIA1GRIA1 isoform 7. (888 aa)
SLC36A2SLC36A2 isoform 1. (486 aa)
ABHD17BAbhydrolase domain containing 17B. (293 aa)
SLC31A2Solute carrier family 31 member 2. (143 aa)
RAB14Ras-related protein Rab-14; Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell [...] (179 aa)
ENTR1SDCCAG3 isoform 2. (362 aa)
CLCN4Chloride channel protein. (760 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (728 aa)
CR201_G0052920GRIPAP1 isoform 14. (643 aa)
RAP2CRAP2C isoform 1. (144 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (701 aa)
ATP11CPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1129 aa)
RFFLT0183779 isoform 1. (369 aa)
ABHD17CABHD17C isoform 2. (207 aa)
ATP11BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (599 aa)
SLC11A2SLC11A2 isoform 12. (573 aa)
ABCG1ATP binding cassette subfamily G member 1. (677 aa)
ENSPPYP00000024753annotation not available (336 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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