(11 nodes) Embryonic skeletal joint morphogenesis network (Pongo abelii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OSR1	OSR1 isoform 1. (265 aa)
	CR201_G0017164	HOXD11 isoform 2. (143 aa)
	CTNNB1	CTNNB1 isoform 2. (781 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	HOXC11	HOXC11 isoform 1. (304 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	BMP7	Bone morphogenetic protein 7. (365 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	OSR2	OSR2 isoform 10. (312 aa)
	HOXA11	HOXA11 isoform 2. (315 aa)
	CR201_G0007803	SHOX2 isoform 5. (151 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP7	ENSPPYP00000006620	ENSPPYP00000012465	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.856
BMP4	COL2A1	ENSPPYP00000006620	ENSPPYP00000005079	Bone morphogenetic protein 4.	Collagen type II alpha 1 chain.	0.410
BMP4	CTNNB1	ENSPPYP00000006620	ENSPPYP00000015644	Bone morphogenetic protein 4.	CTNNB1 isoform 2.	0.598
BMP4	NOG	ENSPPYP00000006620	ENSPPYP00000009271	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.998
BMP4	OSR2	ENSPPYP00000006620	ENSPPYP00000021066	Bone morphogenetic protein 4.	OSR2 isoform 10.	0.459
BMP7	BMP4	ENSPPYP00000012465	ENSPPYP00000006620	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.856
BMP7	CTNNB1	ENSPPYP00000012465	ENSPPYP00000015644	Bone morphogenetic protein 7.	CTNNB1 isoform 2.	0.549
BMP7	NOG	ENSPPYP00000012465	ENSPPYP00000009271	Bone morphogenetic protein 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.988
COL2A1	BMP4	ENSPPYP00000005079	ENSPPYP00000006620	Collagen type II alpha 1 chain.	Bone morphogenetic protein 4.	0.410
CTNNB1	BMP4	ENSPPYP00000015644	ENSPPYP00000006620	CTNNB1 isoform 2.	Bone morphogenetic protein 4.	0.598
CTNNB1	BMP7	ENSPPYP00000015644	ENSPPYP00000012465	CTNNB1 isoform 2.	Bone morphogenetic protein 7.	0.549
CTNNB1	NOG	ENSPPYP00000015644	ENSPPYP00000009271	CTNNB1 isoform 2.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.561
NOG	BMP4	ENSPPYP00000009271	ENSPPYP00000006620	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4.	0.998
NOG	BMP7	ENSPPYP00000009271	ENSPPYP00000012465	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 7.	0.988
NOG	CTNNB1	ENSPPYP00000009271	ENSPPYP00000015644	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	CTNNB1 isoform 2.	0.561
OSR2	BMP4	ENSPPYP00000021066	ENSPPYP00000006620	OSR2 isoform 10.	Bone morphogenetic protein 4.	0.459