STRINGSTRING
ENSPPYP00000013398 ENSPPYP00000013398 RARG RARG BMP4 BMP4 MAPK3 MAPK3 FOXF1 FOXF1 RARA RARA SOX9 SOX9 MAP2K2 MAP2K2 WNT7B WNT7B CTNNB1 CTNNB1 TGFBR2 TGFBR2 LEF1 LEF1 SRF SRF HOXA5 HOXA5 SHH SHH CR201_G0005637 CR201_G0005637 EDA EDA MAPK1 MAPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPPYP00000013398annotation not available (195 aa)
RARGRARG isoform 5. (469 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa)
FOXF1FOXF1 isoform 1. (380 aa)
RARARARA isoform 2. (460 aa)
SOX9SRY-box transcription factor 9. (509 aa)
MAP2K2MAP2K2 isoform 6. (213 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
CTNNB1CTNNB1 isoform 2. (781 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
SRFSerum response factor. (508 aa)
HOXA5HOXA5 isoform 1. (381 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa)
CR201_G0005637RSPO2 isoform 1. (195 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (158 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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