(25 nodes) Epithelial tube branching involved in lung morphogenesis network (Pongo abelii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Others

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protein homology

Your Input:
	YAP1	YAP1 isoform 2. (326 aa)
	FGFR2	Fibroblast growth factor receptor. (656 aa)
	DLG5	DLG5 isoform 1; Belongs to the MAGUK family. (1809 aa)
	HOXA5	HOXA5 isoform 1. (381 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	HHIP	HHIP isoform 1. (647 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	CTNNB1	CTNNB1 isoform 2. (781 aa)
	CELSR1	CELSR1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (2865 aa)
	CTSZ	CTSZ isoform 1; Belongs to the peptidase C1 family. (448 aa)
	LAMA1	LAMA1 isoform 1. (842 aa)
	TBX2	TBX2 isoform 1. (588 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	FOXF1	FOXF1 isoform 1. (380 aa)
	ESRP2	Epithelial splicing regulatory protein 2. (717 aa)
	CTSH	CTSH isoform 1; Belongs to the peptidase C1 family. (295 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	FOXA1	FOXA1 isoform 1. (448 aa)
	NKX2-1	NKX2-1 isoform 1. (401 aa)
	EXT1	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa)
	CR201_G0002480	LAMA1 isoform 5. (479 aa)
	CR201_G0005637	RSPO2 isoform 1. (195 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa)
	KRAS	KRAS proto-oncogene, GTPase. (188 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSPPYP00000006620	ENSPPYP00000015644	Bone morphogenetic protein 4.	CTNNB1 isoform 2.	0.598
BMP4	FGF10	ENSPPYP00000006620	ENSPPYP00000017257	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.682
BMP4	FGFR2	ENSPPYP00000006620	ENSPPYP00000003165	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.528
BMP4	FOXF1	ENSPPYP00000006620	ENSPPYP00000008600	Bone morphogenetic protein 4.	FOXF1 isoform 1.	0.752
BMP4	SHH	ENSPPYP00000006620	ENSPPYP00000020423	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.768
BMP4	SOX9	ENSPPYP00000006620	ENSPPYP00000009638	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.515
CR201_G0002480	LAMA1	ENSPPYP00000024623	ENSPPYP00000010120	LAMA1 isoform 5.	LAMA1 isoform 1.	0.900
CR201_G0005637	CTNNB1	ENSPPYP00000021114	ENSPPYP00000015644	RSPO2 isoform 1.	CTNNB1 isoform 2.	0.467
CTNNB1	BMP4	ENSPPYP00000015644	ENSPPYP00000006620	CTNNB1 isoform 2.	Bone morphogenetic protein 4.	0.598
CTNNB1	CR201_G0005637	ENSPPYP00000015644	ENSPPYP00000021114	CTNNB1 isoform 2.	RSPO2 isoform 1.	0.467
CTNNB1	DLG5	ENSPPYP00000015644	ENSPPYP00000002681	CTNNB1 isoform 2.	DLG5 isoform 1; Belongs to the MAGUK family.	0.502
CTNNB1	FGF10	ENSPPYP00000015644	ENSPPYP00000017257	CTNNB1 isoform 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.499
CTNNB1	FGFR2	ENSPPYP00000015644	ENSPPYP00000003165	CTNNB1 isoform 2.	Fibroblast growth factor receptor.	0.606
CTNNB1	FOXA1	ENSPPYP00000015644	ENSPPYP00000006542	CTNNB1 isoform 2.	FOXA1 isoform 1.	0.497
CTNNB1	KRAS	ENSPPYP00000015644	ENSPPYP00000004987	CTNNB1 isoform 2.	KRAS proto-oncogene, GTPase.	0.715
CTNNB1	SHH	ENSPPYP00000015644	ENSPPYP00000020423	CTNNB1 isoform 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.677
CTNNB1	SOX9	ENSPPYP00000015644	ENSPPYP00000009638	CTNNB1 isoform 2.	SRY-box transcription factor 9.	0.870
CTNNB1	YAP1	ENSPPYP00000015644	ENSPPYP00000004354	CTNNB1 isoform 2.	YAP1 isoform 2.	0.975
CTSH	CTSZ	ENSPPYP00000007609	ENSPPYP00000012490	CTSH isoform 1; Belongs to the peptidase C1 family.	CTSZ isoform 1; Belongs to the peptidase C1 family.	0.472
CTSZ	CTSH	ENSPPYP00000012490	ENSPPYP00000007609	CTSZ isoform 1; Belongs to the peptidase C1 family.	CTSH isoform 1; Belongs to the peptidase C1 family.	0.472