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SEMA4B | SEMA4B isoform 4. (930 aa) | ||||
ROBO2 | ROBO2 isoform 6. (1384 aa) | ||||
EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa) | ||||
WT1 | WT1 isoform 2. (320 aa) | ||||
OVOL2 | Ovo like zinc finger 2. (289 aa) | ||||
FOXH1 | FOXH1 isoform 1. (366 aa) | ||||
LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1000 aa) | ||||
LOXL2 | Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys- 9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member o [...] (549 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (396 aa) | ||||
ENSPPYP00000023667 | annotation not available (104 aa) | ||||
MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (158 aa) | ||||
NOLC1 | NOLC1 isoform 7. (726 aa) | ||||
RPS7 | 40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa) | ||||
FLNA | FLNA isoform 7. (2647 aa) | ||||
ZIC3 | Zic family member 3. (466 aa) | ||||
AMER1 | APC membrane recruitment protein 1. (1136 aa) | ||||
OTUD5 | OTUD5 isoform 2. (533 aa) | ||||
AMELX | AMELY isoform 1. (205 aa) | ||||
NOTCH1 | NOTCH1 isoform 1. (2107 aa) | ||||
CR201_G0027392 | OLFM1 isoform 6. (357 aa) | ||||
ENG | ENG isoform 3. (668 aa) | ||||
AKNA | AKNA isoform 1. (1357 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) | ||||
SEMA4D | SEMA4D isoform 10; Belongs to the semaphorin family. (862 aa) | ||||
BNC2 | BNC2 isoform 1. (1099 aa) | ||||
SCX | SCX isoform 1. (200 aa) | ||||
ENSPPYP00000021204 | annotation not available (300 aa) | ||||
HAS2 | HAS2 isoform 1. (511 aa) | ||||
EXT1 | Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa) | ||||
ZFPM2 | ZFPM2 isoform 1. (1152 aa) | ||||
HEY1 | Hes related family bHLH transcription factor with YRPW motif 1. (304 aa) | ||||
RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) | ||||
SNAI2 | Snail family transcriptional repressor 2. (268 aa) | ||||
CR201_G0033322 | SFRP1 isoform 1. (260 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (822 aa) | ||||
NRG1 | NRG1 isoform 10. (692 aa) | ||||
GATA4 | GATA binding protein 4. (442 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa) | ||||
NOS3 | NOS3 isoform 2. (833 aa) | ||||
EXOC4 | EXOC4 isoform 2. (974 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) | ||||
SEMA3C | Semaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity). (754 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa) | ||||
SEMA3E | SEMA3E isoform 1; Belongs to the semaphorin family. (504 aa) | ||||
SEMA3A | SEMA3A isoform 1; Belongs to the semaphorin family. (771 aa) | ||||
SEMA3D | SEMA3D isoform 1; Belongs to the semaphorin family. (777 aa) | ||||
TWIST1 | Twist family bHLH transcription factor 1. (203 aa) | ||||
HOXA5 | HOXA5 isoform 1. (381 aa) | ||||
TBX20 | TBX20 isoform 1. (447 aa) | ||||
RADIL | RADIL isoform 3. (1062 aa) | ||||
CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa) | ||||
TCF21 | Transcription factor 21. (179 aa) | ||||
HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (337 aa) | ||||
ENSPPYP00000018739 | annotation not available (186 aa) | ||||
BMP5 | BMP5 isoform 1. (453 aa) | ||||
PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1030 aa) | ||||
CUL7 | Cullin-7; Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin- protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as [...] (1723 aa) | ||||
NOTCH4 | NOTCH4 isoform 1. (2000 aa) | ||||
RBM24 | RNA binding motif protein 24. (236 aa) | ||||
EDN1 | EDN1 isoform 1. (212 aa) | ||||
FOXC1 | FOXC1 isoform 1. (332 aa) | ||||
FOXF2 | FOXF2 isoform 1. (184 aa) | ||||
HNRNPAB | HNRNPAB isoform 1. (261 aa) | ||||
CR201_G0004819 | NKX2-5 isoform 1. (210 aa) | ||||
HAND1 | Heart and neural crest derivatives expressed 1. (215 aa) | ||||
ANXA6 | Annexin. (660 aa) | ||||
TCOF1 | TCOF1 isoform 1. (1489 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
SEMA6A | SEMA6A isoform 1; Belongs to the semaphorin family. (1030 aa) | ||||
FBXL17 | FBXL17 isoform 1. (751 aa) | ||||
FAM172A | Family with sequence similarity 172 member A. (416 aa) | ||||
MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (441 aa) | ||||
ISL1 | ISL1 isoform 1. (349 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
GDNF | GDNF isoform 6. (185 aa) | ||||
BASP1 | Brain abundant membrane attached signal protein 1. (227 aa) | ||||
SEMA5A | SEMA5A isoform 1. (1044 aa) | ||||
PDCD6 | Programmed cell death protein 6 isoform X1. (191 aa) | ||||
HAND2 | HAND2 isoform 1. (217 aa) | ||||
SFRP2 | Secreted frizzled related protein 2. (295 aa) | ||||
EDNRA | EDNRA isoform 1; Belongs to the G-protein coupled receptor 1 family. (425 aa) | ||||
SPRY1 | Sprouty RTK signaling antagonist 1. (319 aa) | ||||
PITX2 | Homeobox protein. (317 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (399 aa) | ||||
PKD2 | PKD2 isoform 1. (968 aa) | ||||
CR201_G0036073 | PHOX2B isoform 1. (269 aa) | ||||
TAPT1 | TAPT1 isoform 2. (532 aa) | ||||
ENSPPYP00000016309 | annotation not available (193 aa) | ||||
MSX1 | MSX1 isoform 1. (261 aa) | ||||
HES1 | HES1 isoform 1. (198 aa) | ||||
WWTR1 | WW domain containing transcription regulator 1. (400 aa) | ||||
EOMES | EOMES isoform 3. (704 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
CTNNB1 | CTNNB1 isoform 2. (781 aa) | ||||
SEMA3F | SEMA3F isoform 4; Belongs to the semaphorin family. (755 aa) | ||||
SEMA3B | SEMA3B isoform 6; Belongs to the semaphorin family. (690 aa) | ||||
SEMA3G | SEMA3G isoform 1; Belongs to the semaphorin family. (878 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (473 aa) | ||||
TASOR | FAM208A isoform 4. (1354 aa) | ||||
CR201_G0046097 | KBTBD8 isoform 2. (415 aa) | ||||
CRELD1 | CRELD1 isoform 1. (481 aa) | ||||
ROBO1 | ROBO1 isoform 6. (1612 aa) | ||||
DPPA4 | Developmental pluripotency associated 4. (303 aa) | ||||
POGLUT1 | Protein O-glucosyltransferase 1. (392 aa) | ||||
GSK3B | GSK3B isoform 2; Belongs to the protein kinase superfamily. (380 aa) | ||||
SEMA5B | SEMA5B isoform 1. (1091 aa) | ||||
GBX2 | GBX2 isoform 1. (173 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (422 aa) | ||||
FN1 | FN1 isoform 4. (2445 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1284 aa) | ||||
NRP2 | Neuropilin; Belongs to the neuropilin family. (926 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (766 aa) | ||||
FRZB | Secreted frizzled-related protein 3; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development (By similarity). (325 aa) | ||||
ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) | ||||
EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (733 aa) | ||||
SEMA4C | SEMA4C isoform 1; Belongs to the semaphorin family. (746 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) | ||||
OSR1 | OSR1 isoform 1. (265 aa) | ||||
SIX2 | SIX homeobox 2. (291 aa) | ||||
RTN4 | Reticulon. (1192 aa) | ||||
ACTG2 | ACTG2 isoform 3. (378 aa) | ||||
LOXL3 | LOXL3 isoform 4. (668 aa) | ||||
CR201_G0002974 | SEMA4F isoform 2; Belongs to the semaphorin family. (585 aa) | ||||
POLR1B | DNA-directed RNA polymerase I subunit RPA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). (1135 aa) | ||||
ENSPPYP00000013398 | annotation not available (195 aa) | ||||
DDX17 | DDX17 isoform 4; Belongs to the DEAD box helicase family. (650 aa) | ||||
SOX10 | SOX10 isoform 2. (436 aa) | ||||
TBX1 | TBX1 isoform 2. (213 aa) | ||||
GATA5 | GATA binding protein 5. (397 aa) | ||||
CR201_G0055991 | LAMA5 isoform 1. (2926 aa) | ||||
EDN3 | EDN3 isoform 1. (229 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (365 aa) | ||||
ZFP64 | ZFP64 isoform 2. (629 aa) | ||||
SNAI1 | SNAI1 isoform 1. (263 aa) | ||||
FAM83D | FAM83D isoform 1. (613 aa) | ||||
ACTL10 | ACTL10 isoform 1; Belongs to the actin family. (245 aa) | ||||
PAX1 | PAX1 isoform 1. (447 aa) | ||||
JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) | ||||
TRIM28 | TRIM28 isoform 3. (528 aa) | ||||
TEAD2 | TEA domain transcription factor 2. (447 aa) | ||||
DACT3 | DACT3 isoform 2. (516 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa) | ||||
DLL3 | Delta like canonical Notch ligand 3. (587 aa) | ||||
DAND5 | DAN domain BMP antagonist family member 5. (189 aa) | ||||
NRTN | NRTN isoform 1. (197 aa) | ||||
SEMA6B | SEMA6B isoform 1; Belongs to the semaphorin family. (876 aa) | ||||
AMH | AMH isoform 1. (561 aa) | ||||
BCL2 | BCL2 isoform 1. (238 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (552 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator [...] (467 aa) | ||||
CDH2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic s [...] (906 aa) | ||||
ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1299 aa) | ||||
ENSPPYP00000010097 | annotation not available (194 aa) | ||||
TBX2 | TBX2 isoform 1. (588 aa) | ||||
SOX9 | SRY-box transcription factor 9. (509 aa) | ||||
DDX5 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] (614 aa) | ||||
MEOX1 | Mesenchyme homeobox 1. (254 aa) | ||||
TMEM100 | Transmembrane protein 100. (134 aa) | ||||
NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) | ||||
RFLNB | RFLNB isoform 1. (152 aa) | ||||
FOXF1 | FOXF1 isoform 1. (380 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) | ||||
SOX8 | SRY-box transcription factor 8. (446 aa) | ||||
MESP1 | Mesoderm posterior bHLH transcription factor 1. (269 aa) | ||||
SEMA7A | SEMA7A isoform 1; Belongs to the semaphorin family. (664 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa) | ||||
ACTC1 | Actin alpha cardiac muscle 1. (377 aa) | ||||
GSC | Goosecoid homeobox. (257 aa) | ||||
ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) | ||||
CR201_G0009767 | HIF1A isoform 5. (735 aa) | ||||
SIX4 | SIX4 isoform 1. (698 aa) | ||||
SIX1 | SIX homeobox 1. (284 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (408 aa) | ||||
FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
CR201_G0000883 | HNF1A isoform 7. (347 aa) | ||||
TBX3 | T-box transcription factor 3. (743 aa) | ||||
TBX5 | T-box transcription factor 5. (518 aa) | ||||
CORO1C | Coronin; Belongs to the WD repeat coronin family. (434 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (262 aa) | ||||
ALX1 | ALX homeobox 1. (326 aa) | ||||
ENSPPYP00000005397 | annotation not available (67 aa) | ||||
HMGA2 | High mobility group AT-hook 2. (147 aa) | ||||
ERBB3 | Receptor tyrosine-protein kinase erbB-3; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. (1342 aa) | ||||
ACVRL1 | Serine/threonine-protein kinase receptor R3; Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well (By similarity). (503 aa) | ||||
YAP1 | YAP1 isoform 2. (326 aa) | ||||
WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) | ||||
APLNR | APLNR isoform 1; Belongs to the G-protein coupled receptor 1 family. (380 aa) | ||||
FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
FGFR2 | Fibroblast growth factor receptor. (656 aa) | ||||
CR201_G0023542 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (166 aa) | ||||
SEMA4G | SEMA4G isoform 7; Belongs to the semaphorin family. (811 aa) | ||||
PAX2 | PAX2 isoform 3. (388 aa) | ||||
CYP26C1 | CYP26C1 isoform 2; Belongs to the cytochrome P450 family. (518 aa) | ||||
ACTA2 | ACTA2 isoform 5. (399 aa) | ||||
NODAL | Nodal growth differentiation factor. (347 aa) | ||||
DLG5 | DLG5 isoform 1; Belongs to the MAGUK family. (1809 aa) | ||||
BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) | ||||
RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa) | ||||
NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) | ||||
CPLANE2 | Ciliogenesis and planar polarity effector 2. (258 aa) | ||||
CDC42 | Cell division cycle 42. (191 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
PHACTR4 | Phosphatase and actin regulator 4; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to [...] (687 aa) | ||||
PEF1 | Penta-EF-hand domain containing 1. (284 aa) | ||||
HEYL | Hes related family bHLH transcription factor with YRPW motif like. (328 aa) | ||||
TGFBR3 | TGFBR3 isoform 1. (859 aa) | ||||
SEMA6C | SEMA6C isoform 1; Belongs to the semaphorin family. (932 aa) | ||||
S100A4 | Protein S100; Belongs to the S-100 family. (101 aa) | ||||
ADAM15 | ADAM15 isoform 14. (750 aa) | ||||
EFNA1 | EFNA1 isoform 1; Belongs to the ephrin family. (205 aa) | ||||
SEMA4A | SEMA4A isoform 10; Belongs to the semaphorin family. (709 aa) | ||||
KLHL12 | KLHL12 isoform 2. (567 aa) | ||||
MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa) | ||||
ACTA1 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa) | ||||
NUP133 | NUP133 isoform 1. (1154 aa) |