STRINGSTRING
F11R F11R RAP1A RAP1A PDE2A PDE2A RDX RDX ROBO4 ROBO4 RAP1B RAP1B TJP1 TJP1 PECAM1 PECAM1 FASN FASN TJP3 TJP3 PTPRS PTPRS MYADM MYADM PPP1R16B PPP1R16B CR201_G0013985 CR201_G0013985 MYD88 MYD88 CLDN1 CLDN1 ENSPPYP00000016185 ENSPPYP00000016185 HPSE HPSE EDNRA EDNRA PDE4D PDE4D MARVELD2 MARVELD2 F2RL1 F2RL1 EZR EZR AFDN AFDN CLDN3 CLDN3 RAPGEF1 RAPGEF1 FOXP3 FOXP3 MSN MSN RAP2C RAP2C EDNRB EDNRB RAPGEF2 RAPGEF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F11RF11R isoform 1. (298 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PDE2APhosphodiesterase. (939 aa)
RDXRDX isoform 3. (604 aa)
ROBO4Roundabout guidance receptor 4. (1007 aa)
RAP1BRas-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa)
TJP1TJP1 isoform 1; Belongs to the MAGUK family. (1746 aa)
PECAM1PECAM1 isoform 1. (738 aa)
FASNFASN isoform 1. (2435 aa)
TJP3TJP3 isoform 5; Belongs to the MAGUK family. (807 aa)
PTPRSPTPRS isoform 2. (1616 aa)
MYADMMyeloid-associated differentiation marker. (322 aa)
PPP1R16BPPP1R16B isoform 1. (519 aa)
CR201_G0013985RAP1B isoform 27. (171 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ENSPPYP00000016185annotation not available (59 aa)
HPSEHPSE isoform 1. (545 aa)
EDNRAEDNRA isoform 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
PDE4DPhosphodiesterase. (679 aa)
MARVELD2MARVEL domain containing 2. (559 aa)
F2RL1F2RL1 isoform 1. (397 aa)
EZREZR isoform 1. (586 aa)
AFDNAFDN isoform 9. (1802 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
RAPGEF1RAPGEF1 isoform 1. (1260 aa)
FOXP3FOXP3 isoform 1. (431 aa)
MSNMSN isoform 6. (577 aa)
RAP2CRAP2C isoform 1. (144 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
RAPGEF2RAPGEF2 isoform 1. (1331 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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