(15 nodes) Regulation of cell proliferation involved in heart morphogenesis network (Pongo abelii)

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	CTNNB1	CTNNB1 isoform 2. (781 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	TBX3	T-box transcription factor 3. (743 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	MKS1	MKS1 isoform 7. (343 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	BMP10	BMP10 isoform 1. (424 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
	HES1	HES1 isoform 1. (198 aa)
	HAND2	HAND2 isoform 1. (217 aa)
	ISL1	ISL1 isoform 1. (349 aa)
	ENSPPYP00000018739	annotation not available (186 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
	NOTCH1	NOTCH1 isoform 1. (2107 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP4	ENSPPYP00000013766	ENSPPYP00000006620	BMP10 isoform 1.	Bone morphogenetic protein 4.	0.573
BMP10	BMPR2	ENSPPYP00000013766	ENSPPYP00000014623	BMP10 isoform 1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP10	SMAD4	ENSPPYP00000013766	ENSPPYP00000010297	BMP10 isoform 1.	Mothers against decapentaplegic homolog.	0.434
BMP4	BMP10	ENSPPYP00000006620	ENSPPYP00000013766	Bone morphogenetic protein 4.	BMP10 isoform 1.	0.573
BMP4	BMPR2	ENSPPYP00000006620	ENSPPYP00000014623	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP4	CTNNB1	ENSPPYP00000006620	ENSPPYP00000015644	Bone morphogenetic protein 4.	CTNNB1 isoform 2.	0.598
BMP4	EYA1	ENSPPYP00000006620	ENSPPYP00000020937	Bone morphogenetic protein 4.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.468
BMP4	ISL1	ENSPPYP00000006620	ENSPPYP00000017263	Bone morphogenetic protein 4.	ISL1 isoform 1.	0.466
BMP4	SMAD4	ENSPPYP00000006620	ENSPPYP00000010297	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.878
BMP4	SOX9	ENSPPYP00000006620	ENSPPYP00000009638	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.515
BMP4	TBX3	ENSPPYP00000006620	ENSPPYP00000005697	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.449
BMP4	TBX5	ENSPPYP00000006620	ENSPPYP00000005696	Bone morphogenetic protein 4.	T-box transcription factor 5.	0.464
BMPR2	BMP10	ENSPPYP00000014623	ENSPPYP00000013766	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	BMP10 isoform 1.	0.996
BMPR2	BMP4	ENSPPYP00000014623	ENSPPYP00000006620	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.996
BMPR2	SMAD4	ENSPPYP00000014623	ENSPPYP00000010297	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.872
CTNNB1	BMP4	ENSPPYP00000015644	ENSPPYP00000006620	CTNNB1 isoform 2.	Bone morphogenetic protein 4.	0.598
CTNNB1	ENSPPYP00000018739	ENSPPYP00000015644	ENSPPYP00000018739	CTNNB1 isoform 2.	annotation not available	0.451
CTNNB1	NOTCH1	ENSPPYP00000015644	ENSPPYP00000022176	CTNNB1 isoform 2.	NOTCH1 isoform 1.	0.786
CTNNB1	SMAD4	ENSPPYP00000015644	ENSPPYP00000010297	CTNNB1 isoform 2.	Mothers against decapentaplegic homolog.	0.882
CTNNB1	SOX9	ENSPPYP00000015644	ENSPPYP00000009638	CTNNB1 isoform 2.	SRY-box transcription factor 9.	0.870